Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07226726RecruitingPhase 1
Stem cell exosome treatment for congenital myasthenic syndrome
This trial tests a treatment made from stem cell exosomes (tiny particles that may help repair cells) for people with congenital myasthenic syndrome, a muscle-weakening condition. It aims to see if this treatment is safe and could improve symptoms.
Naples, FloridaAges 18 years+ - NCT07227363Recruiting
Keto diet for PCOS symptoms pilot study
This study tests if a keto diet can improve symptoms of PCOS. You'll follow your normal routine while researchers monitor changes.
Columbus, OhioAges 18–40 - NCT07229521Recruiting
Nattokinase for heart, gut, sleep, and brain health in metabolic syndrome with sleep issues
This study tests whether a supplement called nattokinase can improve heart health, sleep, thinking, and gut bacteria in people with metabolic syndrome and mild-to-moderate sleep apnea. If you have a larger waist, blood pressure or blood sugar issues, or imbalanced cholesterol, and have been diagnosed with mild or moderate sleep apnea, you may be eligible.
TaipeiAges 18 years+ - NCT07230847Recruiting
Healing of drug-coated vs. standard stents in high-bleeding-risk patients
This trial compares two types of stents (a drug-coated stent and a standard drug-eluting stent) in people with acute coronary syndrome who also have a high risk of bleeding. It uses a special camera to look at how the artery heals one month after the stent is placed.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07232134RecruitingPhase 3
Treating AML in children with Down syndrome
This trial tests a treatment plan for children with Down syndrome who have been diagnosed with acute myeloid leukemia (AML) or a related bone marrow condition. The goal is to see how well the therapy works and to help guide doctors in choosing the best approach.
MoscowAges 1 day–18 years - NCT07235215Recruiting
Testing Vivatlac for Irritable Bowel Syndrome
This study tests a product called Vivatlac to see if it can help people with Irritable Bowel Syndrome (IBS). If you have moderate-to-severe IBS and haven't taken probiotics or antibiotics recently, you may be able to join.
JarocinAges 18–65 - NCT07236658Recruiting
Using AI to detect arm problems after breast cancer surgery
This trial uses artificial intelligence (a computer program) to help predict arm and shoulder problems that can happen after breast cancer surgery. It aims to find these issues early so they can be treated better.
AnkaraAges 18 years+ - NCT07236762RecruitingPhase 1
YTS109 cell therapy for severe autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with severe autoimmune diseases like lupus, Sjögren's syndrome, systemic sclerosis, inflammatory myopathy, vasculitis, and antiphospholipid syndrome. It's for those whose disease hasn't improved with standard treatments.
BengbuAges 18–65 - NCT07236801RecruitingPhase 1
Cell therapy for hard-to-treat autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with several autoimmune diseases that have not improved with standard medications. It aims to see if this treatment can help control the disease when other treatments have failed.
Xuzhou, JiangsuAges 18–65 - NCT07238465RecruitingPhase 3
Exploring nervous system function in Down syndrome
This trial studies how the nervous system works in people with Down syndrome. It may help understand differences in body functions and improve future care.
Aurora, ColoradoAges 18–50 - NCT07243821Recruiting
Metabolic syndrome and prediabetes study
This study looks at people with metabolic syndrome or prediabetes to understand how these conditions affect health. You may qualify if you have at least three signs of metabolic syndrome or if your blood sugar levels are higher than normal.
Taipei, Zhongzheng DistAges 18 years+ - NCT07244133Recruiting
Powerball exercise for kids with Down syndrome
This trial tests whether using a Powerball (a small exercise ball) can improve hand strength and coordination in children with Down syndrome. It may help with daily tasks and motor skills.
Lahore, Punjab ProvinceAges 6–10 - NCT07244614Recruiting
Study of ustekinumab or apremilast for Behçet's disease symptoms
This study tests if ustekinumab or apremilast can help control Behçet's disease symptoms like mouth and genital ulcers, skin sores, and joint pain. It may be an option if standard treatments haven't worked well.
BordeauxAges 18 years+ - NCT07247266RecruitingPhase 1
Testing JTE-162 for CAPS (FCAS and MWS)
This study tests an experimental drug called JTE-162 for people with certain types of CAPS (cryopyrin-associated periodic syndrome). The goal is to see if it's safe and can help control symptoms like fever, rash, and joint pain.
North York, OntarioAges 18–80 - NCT07248124Recruiting
Studying muscle response in carpal tunnel syndrome
This study looks at how your muscles react during a specific test for carpal tunnel syndrome. It aims to better understand the condition and could help improve diagnosis.
TarbesAges 18 years+ - NCT07248267Recruiting
Vojta therapy for children with Down syndrome
This study is testing a therapy called Vojta therapy to see if it helps children with Down syndrome move better and walk more easily. It compares the therapy to other supportive care.
Lahore, Punjab ProvinceAges 2–10 - NCT07248371Recruiting
Validating multi-omics for metabolic syndrome diseases
This study is testing a new way to look at health information (multi-omics) to better understand conditions related to metabolic syndrome, like diabetes or heart disease. It may help doctors find more personalized treatments.
TaoyuanAges 20 years+ - NCT07251673Recruiting
Study of Dravet syndrome in children with SCN1A gene changes
This study follows children with Dravet syndrome caused by a specific SCN1A gene change to understand how the condition develops over time. It may help families know more about what to expect.
Paris, Ap-hp / DRCIAges 6 months–21 years - NCT07259252Recruiting
Flu vaccine study for heart attack or unstable angina patients
This study tests whether getting a flu vaccine helps people who recently had a heart attack or unstable angina (acute coronary syndrome). It looks at whether vaccination can reduce future heart problems.
Wuhan, HubeiAges 18–80 - NCT07261787RecruitingPhase 4
Surfactant given in 1 vs. 5 minutes for very preterm babies
This trial compares giving a breathing treatment (surfactant) over 1 minute versus 5 minutes to help very premature babies born before 28 weeks. The goal is to see which timing helps the baby's breathing and heart rate stabilize better.
GrazAges birth–3 days - NCT07275190Recruiting
Machine learning to tell apart two rare diseases
This trial uses computer models (machine learning) to help doctors better distinguish between two rare conditions that both cause high levels of a certain white blood cell (eosinophil). The goal is to make diagnosis faster and more accurate, which could lead to more targeted treatment.
PaviaAges 18 years+ - NCT07277673Recruiting
Exercise plus talk therapy for impotence in men with metabolic syndrome
This trial tests if adding aerobic exercise to cognitive behavioral therapy (talk therapy) can help treat impotence in men who have metabolic syndrome and drink heavily.
Giza, DokkiAges 35–45 - NCT07280468RecruitingPhase 4
Personalized sleep apnea treatment for Down syndrome
This study tests if a treatment chosen based on your specific type of sleep apnea works better for people with Down syndrome. It looks for participants who have sleep apnea but are not already using a CPAP machine regularly.
Tucson, ArizonaAges 6 years+ - NCT07283900RecruitingPhase 2
Vitamin C with chemotherapy for higher-risk MDS
This trial tests whether adding high-dose vitamin C (ascorbate) to a standard chemotherapy drug (azacitidine) helps people with higher-risk myelodysplastic syndrome (MDS). It is for those who have had little or no prior treatment for MDS.
Iowa City, IowaAges 18–99
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.