Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07568067Recruiting
Accelerated Brain Stimulation for Parkinson's Disease
This trial tests a new type of brain stimulation (called temporal interference stimulation) targeted at specific brain regions to help improve Parkinson's disease symptoms. Researchers will use MRI imaging and behavioral assessments to see if this approach can reduce movement problems and improve quality of life.
Guangzhou, GuangdongAges Up to 85 years - NCT07567664Enrolling by invitation
Brain Changes in Neurodegenerative Diseases: A Tracking Study
This research study tracks how brain damage progresses in rare neurodegenerative diseases like frontotemporal dementia, primary progressive aphasia, PSP, CBS, and ALS. Researchers use brain imaging and tests to understand how these diseases spread in the brain, which could help develop better treatments.
Milan, LombardyAges 20–85 - NCT07560280Recruiting
Tinnitus from Jugular Vein Narrowing: Diagnosis and Surgery Study
This study evaluates whether neck vein narrowing causes a specific type of tinnitus (ringing in the ears) and tests surgical treatment. If you have persistent tinnitus and imaging shows a narrowed jugular vein, this trial may help determine if surgery could help.
Beijing, Beijing MunicipalityAges 18–75 - NCT07563842Enrolling by invitation
Defining Abdominal Pressure Complications After Surgery
This study is updating medical definitions for a serious condition called abdominal compartment syndrome—where pressure builds up in the belly after surgery or critical illness. The research involves expert doctors and patients who have experienced this condition, working together to clarify what it is and how to recognize it.
LublinAges 18 years+ - NCT07566377RecruitingPhase 2
Cord Blood Transplant for Children and Young Adults With Blood Cancer
This study tests whether using cord blood stem cells (collected from umbilical cords after birth) can help treat high-risk blood cancers in children and young adults when a matched donor is not quickly available. Cord blood transplants may help prevent cancer from coming back.
New York, New YorkAges Up to 26 years - NCT07565220RecruitingPhase 1
Thiotepa-based stem cell transplant for blood cancers
This trial tests a new chemotherapy preparation (using thiotepa) before a stem cell transplant from a matched donor to treat blood cancers like leukemia and myelodysplastic syndrome. The goal is to improve survival while reducing severe side effects.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07563998Recruiting
Fast heart attack blood test in the ambulance
This study tests whether a quick blood test done by paramedics in the ambulance can safely rule out a heart attack in patients with chest pain or similar symptoms. The goal is to help patients get faster, more accurate care before reaching the hospital.
Aarhus NAges 18 years+ - NCT06734988Recruiting
Esophageal Pressure Study for ARDS on Ventilators
This study looks at how well a special pressure measurement in your food pipe (esophageal pressure) works in people with severe lung injury (ARDS) who are on a breathing machine. It may help doctors improve ventilator settings for better lung recovery.
Sapporo, HokkaidoAges 16 years+ - NCT06167239Recruiting
Breathing muscle training for Guillain-Barre patients on ventilators
This trial compares two methods to help people with Guillain-Barre syndrome who are having trouble breathing on their own after being on a ventilator. It tests if adjusting the ventilator's sensitivity or doing specific breathing muscle exercises can improve blood oxygen levels and help them wean off the machine.
CairoAges 20–55 - NCT06737900Recruiting
Jandas vs PNF for pain and mobility in lower back pain
This study compares two physical therapy methods—Jandas Approach and PNF (Proprioceptive Neuromuscular Facilitation)—to see which works better for reducing lower back pain, improving movement, and making daily activities easier. It is for adults with ongoing back pain and specific muscle tightness or weakness.
Lahore, Punjab ProvinceAges 25–40 - NCT06736756Recruiting
Stretching hip muscle to help with knee pain
This trial tests if stretching the tensor fascia lata muscle (near your hip) changes how the muscle on the inside of your kneecap works. It is for people who have front knee pain without a specific injury, especially when doing things like running, squatting, or climbing stairs.
CairoAges 18–30 - NCT07558265Recruiting
Comparing breathing support methods in the emergency department
This study tests two common ways to help people who are having trouble breathing in the emergency room: a face mask that pushes air into the lungs (non-invasive positive pressure ventilation) or high-flow oxygen through small tubes in the nose (high-flow nasal oxygen). The goal is to find which method works better to avoid needing a breathing tube.
Tucson, ArizonaAges 18 years+ - NCT07556952RecruitingPhase 4
Dexamethasone to reduce pain after breast removal surgery
This study tests whether dexamethasone (a common anti-inflammatory medication) can reduce pain after mastectomy (surgical removal of breast tissue). Researchers want to see if it helps patients recover with less pain and potentially fewer pain medications.
Montreal, QuebecAges 18–75 - NCT07552038Recruiting
Dental Care Management for People Living With HIV
This study looks at how dentists can best care for people with HIV. Researchers will review dental and health records at hospitals in the Pays de la Loire region to understand what works best for keeping teeth and gums healthy when you have HIV.
Nantes, NantesAges 18 years+ - NCT07555119Recruiting
Home Sleep Testing: Night-to-Night Measurement Variability Study
This study measures how sleep breathing patterns vary from night to night using home sleep testing. It helps researchers understand if portable sleep tests give consistent and reliable results.
BernAges 18 years+ - NCT07551999Recruiting
Voice Analysis Tool for ME/CFS Diagnosis and Monitoring
This study tests a smartphone app that analyzes your voice to help diagnose and track myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)—a condition causing extreme tiredness and other symptoms. Researchers want to see if voice patterns can be a simple, at-home way to monitor your condition over time.
Rochester, MinnesotaAges 18 years+ - NCT07551960Enrolling by invitation
Testing a Health Risk Prevention Platform for Adults
This study tests a digital platform called STELA that helps adults reduce their risk of heart disease and stroke by identifying and managing modifiable health factors like diet, exercise, and stress. You'll complete health assessments online to see if this preventive approach works.
Třinec, Moravian-Silesian RegionAges 18–80 - NCT07552519Recruiting
Patient Outcomes in Spinal Disease Treatment
This study tracks how patients feel and function after receiving treatment for spinal disease (which may include procedures like spinal cord stimulation). Researchers want to understand what matters most to patients during their recovery.
Hasselt, LimburgAges 18 years+ - NCT06644261RecruitingPhase 4
Comparing two methods of nerve block for pelvic pain
This study compares two ways to give a pudendal nerve block—one through the vagina, one through the buttock with X-ray guidance—to see which works better for women with pudendal neuralgia (nerve pain in the pelvic area). It may help find a more effective and comfortable treatment option.
Louisville, KentuckyAges 18 years+ - NCT06732674Recruiting
Home-based care for lung disease in rheumatic conditions
This trial tests whether people with lung disease caused by a rheumatic condition can safely manage their care at home using a smartphone or tablet. It aims to see if home monitoring is as effective as in-person visits for keeping your lungs healthy.
OsloAges 18 years+ - NCT07548944Recruiting
How Electrical Stimulation Affects Your Vision
This study watches how a treatment called transcorneal electrical stimulation (TES)—which uses gentle electrical pulses on your eye—affects your vision in the short term. You'll be observed while using the OkuStim device, and researchers will ask about any improvements you notice in your sight.
Frankfurt am MainAges 18 years+ - NCT07546084Recruiting
Exercise Program for Rotator Cuff Shoulder Pain
This study tests whether a special exercise program that trains you to focus your attention in different ways can reduce shoulder pain and improve function. You'll do exercises designed to help your rotator cuff (the muscles that stabilize your shoulder) while learning to shift your mental focus during movement.
IstanbulAges 18–65 - NCT07548203Recruiting
Treatments for Dark Spaces Between Teeth
This study tests different ways to fix dark triangular gaps that appear between teeth below the gum line. These gaps can affect how your smile looks and may trap food. The trial will compare treatment options and follow your results over 6 months.
CairoAges 18–50 - NCT07547605RecruitingPhase 4
Comparing PRP, Steroid, and Combined Injections for Neck and Shoulder Pain
This study tests three different injection treatments for upper trapezius myofascial pain (a specific type of muscle knot in your neck/shoulder area). Researchers will compare platelet-rich plasma (PRP, made from your own blood), a steroid injection, and a combination of both to see which works best for pain relief.
Kyrenia, KeryneiaAges 18–65
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.