Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,057 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07493538RecruitingPhase 2
Blood stem cell transplant with lower-intensity chemo for blood cancers
This trial tests a stem cell transplant using milder chemotherapy (treosulfan and fludarabine) followed by a drug called cyclophosphamide to prevent graft-versus-host disease. It aims to make transplant safer for people with blood diseases who cannot handle standard high-dose chemotherapy.
Minneapolis, MinnesotaAges 2–75 - NCT05845424RecruitingPhase 4
High-intensity cholesterol pills for people with silent calcium
This trial studies whether high-intensity statin plus ezetimibe can improve heart health in people who do not have symptoms but have calcium buildup in their heart arteries. It may help lower cholesterol and reduce future heart risks for the right participants.
SeoulAges 40 years+ - NCT07485361Recruiting
Brain scanning in disorders of consciousness
This trial uses a portable brain scanner (fNIRS) to study brain activity in people with disorders of consciousness, like coma or minimally conscious states. It may help doctors better understand and track recovery in these patients. Healthy volunteers are also needed as a comparison group.
Los Angeles, CaliforniaAges 18 years+ - NCT07484594Recruiting
Trunk stabilization plus knee rehab for knee-spine syndrome
This trial tests whether adding trunk stabilization exercises to standard knee osteoarthritis rehab can improve outcomes for people with both knee pain and low back pain. It may help if you have moderate knee arthritis and have had back pain for at least 3 months.
Islamabad, ALAges 40–60 - NCT06775535Recruiting
Spinal cord stimulation trial for chronic pain
This trial tests a closed-loop spinal cord stimulator that adjusts stimulation based on nerve signals. It may help people with chronic pain who are already scheduled to try this type of device.
RoeselareAges 18 years+ - NCT06172335Recruiting
Testing fish oil for heart health in people with belly fat
This study tests whether a type of fish oil can help reduce plaque buildup in arteries, focusing on people with high triglycerides and extra belly fat.
OsloAges 20–70 - NCT06781437Recruiting
Lymphoma medical record review study
This study looks back at the medical records of people with lymphoma to learn more about the disease. It does not involve any new treatments or tests—just reviewing what happened in the past.
Bologna, BolognaAges 18 years+ - NCT06780514Recruiting
Exercise testing for girls with Turner syndrome
This study will have girls with Turner syndrome do a cardiopulmonary exercise test (a special bike or treadmill test) to check how their heart and lungs work during exercise. It may help doctors better understand fitness and health in Turner syndrome.
GhentAges 8–18 - NCT07473804Recruiting
Salt loss in newborns: beyond common adrenal issues
This study looks at babies who lose too much salt (hyponatremia) due to hormone problems in the first two months of life. It aims to learn more about conditions other than the common one (21-hydroxylase deficiency).
BolognaAges 1–35 - NCT07479056Recruiting
Fexuprazan to prevent stomach bleeding in heart patients on two blood thinners
This trial tests whether fexuprazan can prevent upper gastrointestinal bleeding in people at high risk who need two antiplatelet drugs for at least 6 months after a heart stent. If you are on dual antiplatelet therapy after a stent and have risk factors like older age, low weight, or history of ulcers, this study may help protect your stomach.
Seoul, Eunpyeong-guAges 20 years+ - NCT07472842Recruiting
Study on outcomes for endometriosis in emergency care
This study follows women who come to a specific hospital's emergency department with known endometriosis or symptoms that might be endometriosis, to learn more about their health outcomes over time.
CréteilAges 18 years+ - NCT07471867RecruitingPhase 4
Testing a new stomach medicine for heart patients on clopidogrel
This trial tests if a new stomach acid medicine (Zastaprazan) affects how well clopidogrel works in heart patients who have had a stent placed. It aims to help people who need both clopidogrel and a stomach acid drug after a procedure.
Yongin-si, Gyeonggi-doAges 19 years+ - NCT05601726RecruitingPhase 1/Phase 2
Study of a new drug for hard-to-treat AML or high-risk MDS
This early study tests a new medicine (ABD-3001) to see if it’s safe and tolerable, how the body handles it, and whether it shows early signs of helping people with relapsed or hard-to-treat AML or high-risk MDS. It may be an option if standard treatments have already failed and you can’t receive a stem cell transplant.
Marseille, FranceAges 18 years+ - NCT06155708Recruiting
Ketone drink study for women with PCOS
This study tests if a special ketone drink can help women with polycystic ovary syndrome (PCOS). Researchers want to see if it improves health markers related to the condition.
Montreal, QuebecAges 18–40 - NCT06688214Recruiting
Kinesiology taping and shoulder exercises for shoulder pain
This trial tests if kinesiology taping (a special type of tape applied to the shoulder) plus exercises that strengthen the shoulder blades works better than just exercises alone for people with shoulder impingement syndrome (a common cause of shoulder pain). You may qualify if you have had pain on the front or side of your shoulder for at least 3 months and have certain positive tests from a physical therapist.
Lahore, Punjab ProvinceAges 18–55 - NCT06787560RecruitingEarly Phase 1
CAR-T cells and stem cell transplant for blood diseases
This trial tests a new approach for people with non-cancerous blood and immune system diseases. It uses your own engineered immune cells (CAR-T cells) to prepare your body for a stem cell transplant from a relative.
Hangzhou, ZhejiangAges Any age - NCT05895838RecruitingPhase 3
Trial for medicines after out-of-hospital cardiac arrest
This Phase 3 trial studies treatments given after a person survives an out-of-hospital cardiac arrest to improve recovery and survival. It is for patients who stay unconscious for a short time after circulation returns, and who meet safety conditions.
Copenhagen, Capital Region of DenmarkAges 18 years+ - NCT07464093Recruiting
Pilates for joint hypermobility pain
This trial tests if a special Pilates program can reduce pain in people with hypermobile Ehlers-Danlos syndrome or hypermobility spectrum disorder. You must have had pain for at least 3 months and be able to get on and off the floor on your own.
Chestnut Hill, MassachusettsAges 18 years+ - NCT07468461Recruiting
Camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome study
This study looks at children with CACP syndrome, a rare genetic condition, to learn more about how the condition affects the body over time.
BariAges Up to 18 years - NCT07463729Recruiting
Back pain study using biofeedback training
This trial tests a stabilization training program using biofeedback (a device that shows you how your muscles are working) to treat chronic low back pain. It may help you strengthen the muscles supporting your spine and reduce your pain.
Tarnów, MałopolskaAges 30–65 - NCT07469592Recruiting
Mindfulness and music therapy for stem cell transplant patients
This trial tests a combined mindfulness and music therapy program delivered through an app or website. It aims to help patients cope with the stress of stem cell transplant for blood cancers like leukemia or lymphoma.
Miami, FloridaAges 18 years+ - NCT07465159Recruiting
Prehabilitation for frail patients before hip or knee replacement
This study tests whether a 'prehabilitation' program (tailored exercise and nutrition support before surgery) helps older patients who are frail recover better after hip or knee replacement. Participants will be randomly assigned to either the prehabilitation group or the usual care group.
ReykjavikAges 70 years+ - NCT07466446Recruiting
Tracking movement after ICU to support recovery
This study uses a small device (accelerometer) to track your movement after leaving the ICU. It aims to see if monitoring physical activity can help improve recovery for patients at higher risk of setbacks.
EdinburghAges 18 years+ - NCT07464106Recruiting
Tricuspid valve treatment study for older adults
This study tests if a less invasive tricuspid valve repair or replacement can protect kidney function and improve physical activity in older adults with severe tricuspid valve leakage.
StuttgartAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,057 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.