Clinical trials
Dry Eye clinical trials
Below are recruiting dry eye clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06848829Recruiting
Tear Test in Women With and Without Menopause
This study compares a simple tear test between women going through menopause and those who aren’t. It helps researchers understand how menopause may affect eye moisture.
Taichung, TaiwanAges 20–65 - NCT07332988Enrolling by invitation
Light therapy for dry eyes in Graves' disease
This trial tests if low-level light therapy can improve dry eye symptoms in people with Graves' disease whose dry eyes haven't gotten better with standard treatments like artificial tears.
Iași, IaşiAges 18 years+ - NCT07323264Recruiting
Creating a dry eye test for cataract patients
This research study aims to develop better ways to diagnose and manage dry eye disease in people who need cataract surgery. If you have dry eye or not, your participation will help create better care plans.
SingaporeAges 21–99 - NCT07297849Recruiting
Eyelid closure effect on cornea measurement
This trial tests whether closing the eyelids changes the accuracy of a cornea measurement tool. It may help people whose cornea measurements are flagged as "warning" by the device.
Vienna, State of ViennaAges 18 years+ - NCT07277257RecruitingPhase 4
New dry eye treatment for people with Sjögren's syndrome
This study tests a new treatment for dry eye disease caused by Sjögren's syndrome. It may help people who still have dry eye symptoms even when using artificial tears.
Venice, FloridaAges 18 years+ - NCT07229001Enrolling by invitation
Treating Severe MGD in Children and Teens
This trial studies a treatment for severe Meibomian Gland Disease (MGD) in children and teens. MGD affects the tiny oil glands in your eyelids, which can cause dry, irritated eyes. The goal is to find a safe and effective way to help young patients with this condition.
Chicago, IllinoisAges 6–18 - NCT07173530Recruiting
Low-level light therapy for dry eye & skin pigmentation
This study tests whether low-level light therapy can improve dry eye symptoms caused by blocked oil glands (Meibomian Gland Dysfunction). It also looks at how the treatment affects skin pigmentation under the eyes.
Houston, TexasAges 18 years+ - NCT07155057Recruiting
Dry eye gel for cataract surgery patients
This study tests a gel placed into the tear drain to treat dry eye in people who are also getting cataract surgery. You may be able to join if you have dry eye and are having cataract surgery.
Sioux Falls, South DakotaAges 22 years+ - NCT07118241RecruitingPhase 2
Testing a new eye drop for Sjögren's dry eye
This trial tests a new eye drop made from a natural protein (rhPRG4) to see if it safely and effectively relieves dry eye symptoms in people with Sjögren's syndrome. You'll be randomly assigned to receive the study drop or a placebo (inactive) drop for several weeks.
Sydney, New South WalesAges 18–80 - NCT06964269RecruitingPhase 4
Acthar Gel for dry eye and autoimmune disease
This trial tests a new injectable medicine, Acthar Gel, for moderate to severe dry eye and eye pain linked to autoimmune disease. It aims to see if the drug can relieve these symptoms safely.
Nashville, TennesseeAges 18–85 - NCT07109609Enrolling by invitationPhase 2
Testing Menthol on Skin to Increase Tears
This study tests whether applying menthol to the skin on your cheeks can help increase tear production. If you have dry eyes but are not under an eye doctor's care for it, this trial might be a fit.
Toronto, OntarioAges 18 years+ - NCT07113210RecruitingPhase 4
Quality of life with Qlosi eye drops for presbyopia
This trial tests whether a new prescription eye drop called Qlosi improves the quality of life for people with presbyopia (age-related trouble seeing up close). You will use the drops regularly and answer questions about your vision and daily activities.
Medina, MinnesotaAges 45–64 - NCT02585414Recruiting
Eye scans to study dry eye in adults
This study uses a special eye scan (OCT) to measure the tear film in healthy adults and in people with dry eye. It may help researchers understand what’s different in dry eye and how well the scan reflects dry eye symptoms.
ViennaAges 18 years+ - NCT06977724RecruitingPhase 1
Testing a new drug for lupus, sjogren's, and rheumatoid arthritis
This study tests an experimental medicine given by IV infusion to see if it is safe and helps reduce symptoms of lupus, sjogren's disease, or rheumatoid arthritis. It is an early-phase trial, so the main goals are checking side effects and how the drug behaves in the body, but it will also look at how well it works.
Avon Park, FloridaAges 18–75 - NCT06763731RecruitingPhase 4
Optimizing the eye surface with Systane COMPLETE before cataract surgery
This study tests whether using Systane COMPLETE eye drops before cataract surgery can improve the eye surface in people with dry eye. If you have dry eye and are scheduled for cataract surgery, this trial may help improve your eye comfort and surgery outcomes.
Taipei, TaiwanAges 20–85 - NCT06655441RecruitingPhase 4
Trehalose eye drops for dry eye disease
This study tests if a special sugar-based eye drop called trehalose can improve the protective layer of the eye in people with moderate to severe dry eye. It might help strengthen the cornea and reduce discomfort.
Fullerton, CaliforniaAges 18 years+ - NCT06371300Recruiting
Red vs Blue Light for Dry Eye With Mites
This study tests whether a special light (photobiomodulation) using red or blue light can help people with dry eye that is caused by both blocked oil glands and tiny eyelash mites. You'd receive 3 treatments, and we'd check how your eyes feel for a month after.
AucklandAges 18 years+ - NCT05632887Recruiting
Testing how eyeliner changes eye tears
This study compares how eyeliner affects your tears—like tear makeup, how much your eyes produce, and how long the tear layer stays stable. You might help researchers understand whether eyeliner use impacts eye comfort or dryness.
Wuhan, HubeiAges 20–35 - NCT06220474Recruiting
Radiofrequency treatment for stubborn dry eye
This trial tests a non-invasive radiofrequency treatment for people with meibomian gland dysfunction (a type of dry eye) that hasn't improved with standard treatments. It aims to see if this therapy can safely help your eyes feel better.
Hong KongAges 18 years+ - NCT04129021Recruiting
Eye imaging test with fast detailed scans
This trial studies whether a new, very high-resolution and high-speed eye scan can be used for people with eye problems or for healthy volunteers. It may help doctors better “see” eye structures more clearly to guide care.
ParisAges 18 years+ - NCT04946721Recruiting
Study of eye-surface disease tests and targeted treatment
This study looks at how an “ocular surface” condition can be identified using tests (biomarkers) and how a targeted treatment may help. You may qualify if you’re an adult receiving eye care at specific University of Maryland locations.
Baltimore, MarylandAges 18 years+ - NCT04198740Recruiting
Test tear fluid and eye chemistry patterns in eye surface diseases
This study looks at tiny chemical patterns in tear fluid to better understand different causes of eye surface problems. Your participation may help researchers compare healthy eyes with conditions like dry eye, infections, or allergies.
Montreal, QuebecAges 18 years+ - NCT03135327Recruiting
Eye scans study to compare brain and eye health
This study uses detailed eye imaging to look for patterns that may go along with conditions like Alzheimer’s disease, memory problems, multiple sclerosis, or eye/vascular issues. It may help researchers better understand how eye findings relate to health and disease.
Miami, FloridaAges 18–99 - NCT04339764RecruitingPhase 1/Phase 2
iPS cell eye transplant for dry macular degeneration
This early-phase study tests whether transplanting lab-made retinal cells from your own body can slow vision loss from geographic atrophy caused by dry age-related macular degeneration. It involves eye surgery and frequent follow-up to check safety and early signs of benefit.
Baltimore, MarylandAges 55–95
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Common questions
- Are there clinical trials for dry eye?
- Yes. Clin2 currently lists 97 recruiting dry eye studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dry eye trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dry eye trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.