Clinical trials
Early Breast Cancer clinical trials
Below are recruiting early breast cancer clinical trials, each written for real people, not researchers. We’re tracking 430 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06185569Recruiting
French study on outcomes in HR+/HER2- early breast cancer patients with Oncotype DX
This study looks at how well treatments work for people with early-stage, hormone receptor-positive, HER2-negative breast cancer when the Oncotype DX test helps guide therapy. It aims to understand real-world outcomes in French patients.
BesançonAges 18 years+ - NCT05891093RecruitingPhase 3
Fluzoparib plus hormone therapy after surgery for breast cancer
This Phase 3 trial tests whether fluzoparib added to standard hormone (endocrine) therapy after early breast cancer surgery can improve outcomes and safety. It may help patients whose tumors are ER-positive, HER2-negative, and a specific SNF3 subtype.
Beijing, Beijing MunicipalityAges 18–70 - NCT05861271RecruitingPhase 2
Adjuvant pyrotinib plus capecitabine for tiny HER2 breast cancer
This trial studies whether adding pyrotinib and capecitabine after surgery can lower the risk of cancer coming back in people with very small, lymph-node–negative, HER2-positive breast cancer. It’s for patients who fit specific tumor size and HER2 test results and who can safely take chemotherapy-like medicines and stay on contraception during treatment.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05433753Recruiting
Study for leftover cancer DNA in HER2-positive early breast cancer
This study looks for tiny traces of cancer after treatment by testing blood for “ctDNA,” which is leftover cancer DNA. It includes people with HER2-positive early breast cancer who are getting chemotherapy before surgery to see if this blood test can detect signs of remaining disease.
Chuo-ku, TokyoAges 20 years+ - NCT06341894RecruitingPhase 2
Dalpiciclib and hormone therapy for early breast cancer
This trial tests a new pill (dalpiciclib) combined with hormone therapy for women with early-stage, hormone receptor positive/HER2-negative breast cancer. The goal is to see if this combination can lower the chance of cancer coming back after surgery.
Nanjing, JiangsuAges 18–75 - NCT04603209Recruiting
Check-in registry for radiation during breast-conserving surgery
This registry study tracks people with early-stage, single-area breast cancer to understand outcomes when radiation is given during breast-conserving surgery. It may help doctors improve treatment planning for patients like you.
Santa Monica, CaliforniaAges 18 years+ - NCT04790305RecruitingPhase 4
Huaier granules with standard therapy for early triple-negative breast cancer
This trial looks at whether adding Huaier granules to usual after-surgery treatment can improve outcomes for people with high-risk early-stage triple-negative breast cancer. It focuses on whether the added supplement is safe and helpful after standard care.
Hefei, AnhuiAges 18–70 - NCT07803081Recruiting
Radiotherapy after breast surgery without lymph node biopsy
This study looks at how well radiation therapy works for women with early-stage breast cancer who had breast-conserving surgery but did not have their underarm lymph nodes removed. It aims to understand long-term outcomes and help guide future treatment decisions.
SeoulAges 19 years+ - NCT04353557Recruiting
Blood test monitoring in early-stage breast cancer
This trial uses a special blood test to track cancer signals (called ctDNA) during and after treatment for early breast cancer. It aims to see whether monitoring these signals can help guide follow-up and treatment decisions.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06236269RecruitingPhase 2
Sacituzumab Govitecan for HR+/HER2- advanced breast cancer
This trial tests a drug called Sacituzumab Govitecan for people with HR+/HER2- advanced or metastatic breast cancer that has stopped responding to a CDK4/6 inhibitor. It looks at whether the drug can slow down the cancer and requires you to have a tumor biopsy.
Badalona, BarcelonaAges 18 years+ - NCT06508216RecruitingPhase 1/Phase 2
New drug combo for early relapsed triple-negative breast cancer
This trial tests experimental drugs for people with triple-negative breast cancer that came back within 12 months of finishing initial treatment. The goal is to see if these drugs are safe and can shrink or slow the cancer.
VillejuifAges 18 years+ - NCT07796880RecruitingPhase 2
Study of a new drug with hormone therapy before breast cancer surgery
This trial tests a new drug called culmerciclib when given with hormone therapy before breast cancer surgery. The goal is to see if this combination can shrink tumors and improve outcomes for patients with hormone-receptor-positive, HER2-negative breast cancer.
Guangzhou, GuangdongAges 18–70 - NCT07797218RecruitingPhase 3
Comparing two drug combinations before breast cancer surgery
This study is comparing two different drug combinations given before breast cancer surgery. The goal is to see which one shrinks tumors more effectively. This type of treatment is called 'neoadjuvant' therapy.
ShanghaiAges 18–70 - NCT04679454Recruiting
One-dose pre-surgery radiation for early breast cancer
This study tests whether giving a single dose of radiation before breast surgery can be safe and effective for early-stage breast cancer. It may help by shrinking or treating the tumor right before the operation, depending on your case.
MilanAges 18 years+ - NCT06185972RecruitingPhase 2
MRI-guided ultrasound radiation for breast and chest cancer
This trial tests a new way to give radiation therapy using MRI imaging and ultrasound to make the radiation more targeted and potentially safer. If you have chest-wall or breast cancer and are already scheduled for radiation, this approach might offer a more precise treatment option.
Toronto, OntarioAges 18 years+ - NCT06633601RecruitingPhase 1
Ultrasound and microbubbles with radiation for breast cancer
This trial tests a new way to combine radiation therapy with ultrasound and tiny bubbles to treat breast cancer that has spread to the chest wall or is advanced. It aims to make radiation more effective and safer.
Toronto, OntarioAges 18 years+ - NCT07718841Recruiting
Blood test monitoring for early-stage breast cancer
This study uses a simple blood test called liquid biopsy to monitor cancer DNA in people with early-stage breast cancer before and during treatment. The goal is to see if this test can help guide treatment and improve outcomes.
San Sebastián, GuipúzcoaAges 18 years+ - NCT05935150Recruiting
Skipping lymph node surgery in early breast cancer
This trial studies whether you can safely avoid a lymph node biopsy in the armpit for early breast cancer when scans and exams look negative. It may reduce surgery-related side effects while still keeping cancer care on track.
Nanjing, JiangsuAges 18–70 - NCT07711847Recruiting
Prone positioning for faster breast radiation therapy
This trial tests a personalized prone-immobilization device for partial breast radiation after surgery. It aims to make treatment more comfortable and accurate for patients who have had breast-conserving surgery.
New York, New YorkAges 40 years+ - NCT01993498Recruiting
Study side effects of cancer treatment in localized breast or lung cancer
This study looks at long-term side effects from standard cancer treatments and how they affect daily life and resources. It may help improve care for people with breast or lung cancer that has not spread.
VillejuifAges 18 years+ - NCT07690852Recruiting
Environmental exposures and breast cancer risk study
This study looks at how environmental exposures might affect breast cancer risk. It includes women at average risk, high risk, or those diagnosed with breast cancer before age 50, as well as healthcare providers.
Duarte, CaliforniaAges 18 years+ - NCT06676761Recruiting
Study of a new minimal scar mastectomy
This trial is testing a new surgical technique that leaves a smaller scar during mastectomy for breast cancer. It may be a good option if you want to keep the scar as small as possible.
SingaporeAges Any age - NCT06677944RecruitingPhase 2
Radiation before surgery for early-stage breast cancer
This trial tests giving radiation to the tumor area before surgery for women with early-stage, hormone-sensitive breast cancer. The idea is to see if giving radiation first can help protect healthy tissue while still being effective.
SeoulAges 45 years+ - NCT06679387RecruitingPhase 2
Memantine to prevent paclitaxel nerve damage in breast cancer
This trial tests whether the drug memantine can help prevent or reduce nerve pain and other side effects caused by the chemotherapy drug paclitaxel in breast cancer patients. If you are about to start weekly paclitaxel, this study may offer extra protection to your nerves.
CairoAges 18 years+
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Common questions
- Are there clinical trials for early breast cancer?
- Yes. Clin2 currently lists 430 recruiting early breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a early breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a early breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.