Clinical trials
ECMO clinical trials
Below are recruiting ecmo clinical trials, each written for real people, not researchers. We’re tracking 72 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06274411Recruiting
Backup ECMO for high-risk heart stenting
This trial studies a safe, backup ECMO machine for people with very weak hearts or complex blockages who need high-risk stenting. It helps keep your blood pumping if your heart struggles during the procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05640635Recruiting
Testing inflammation changes in people on ECMO
This study looks at inflammation during ECMO (a heart-lung bypass machine) and while people are being weaned off it. It may help doctors better understand which patients are improving safely during ECMO and when to reduce support.
Tübingen, Baden-WurttembergAges 18 years+ - NCT06615492Recruiting
Lung transplant study: comparing two ECMO methods
This study compares two ways of using a heart-lung machine (ECMO) during lung transplant surgery. The goal is to see if using ECMO only when needed works as well as using it for everyone. This could help reduce risks and improve recovery.
Edmonton, AlbertaAges 18 years+ - NCT07309029Recruiting
ECMO support during high-risk TAVR heart valve procedure
This trial tests whether placing patients on ECMO (a heart-lung support machine) before a high-risk TAVR valve replacement can improve safety and outcomes. It is for people who are at very high risk due to low blood pressure, severe heart or lung problems, or complex valve anatomy.
Detroit, MichiganAges 18–100 - NCT05163925Recruiting
Study of a heart-lung device for emergency life support
This trial looks at using a specific heart-lung support machine (the EUROSETS ECMOLIFE system) for adults who need urgent “extra” circulation support. It may help clinicians understand how well the device works in serious situations like shock, cardiac arrest, or after heart surgery.
ViennaAges 18 years+ - NCT07141524Enrolling by invitation
Breathing and blood flow optimization during heart-lung machine support
This study looks at ways to improve breathing and blood flow in patients who are on a heart-lung machine (ECMO) for severe heart problems. It may help doctors better manage care for people in intensive care.
Boston, MassachusettsAges 18 years+ - NCT06560164Recruiting
Comparing blood transfusion levels in ECMO patients
This trial tests whether giving more or fewer red blood cell transfusions is better for adult patients on ECMO (a machine that helps your heart and lungs work). The goal is to find the best transfusion approach to improve outcomes.
Vienna, State of ViennaAges 18 years+ - NCT06080074RecruitingPhase 2
Emergency heart-lung machine study for children with severe heart failure
This study tests a specific heart-lung machine called Cardiohelp to help children with severe heart failure. It looks at how well the machine works and whether a blood thinner (either heparin or bivalirudin) is safer and more effective.
Palo Alto, CaliforniaAges birth–16 years - NCT06676085Recruiting
New ECMO blood-thinning strategy with nafamostat
This study tests a new way to manage blood-thinning medicine during ECMO (a machine that helps your heart and lungs). The goal is to see if using a drug called nafamostat in the ECMO circuit along with lower doses of a standard blood thinner can reduce side effects like bleeding.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05547698Recruiting
ECMO versus off-pump double lung transplant care
This study compares two ways of supporting the lungs and heart around the time of a double lung transplant: venoarterial ECMO versus an off-pump approach. It may help your team choose the safest support method based on your heart-lung pressures and surgical plan.
Louisville, KentuckyAges 18 years+ - NCT07016685Recruiting
ECMO outcomes after emergency chest surgery
This study looks at how well patients recover after needing a heart-lung bypass machine (VV-ECMO) during or right after emergency chest surgery. It aims to understand what affects their prognosis.
AmiensAges 18 years+ - NCT07726953Recruiting
Full-course ECMO for moderate-to-severe ARDS
This trial tests a full-course strategy using a heart-lung bypass machine (ECMO) for people with moderate-to-severe acute respiratory distress syndrome (ARDS), a serious lung condition. The goal is to see if starting and continuing ECMO throughout treatment improves recovery.
BeijingAges 18 years+ - NCT03948048Recruiting
ECMO timing study for children with hard-to-treat septic shock
This trial looks at whether and when a heart-lung machine called ECMO should be used in children whose septic shock is not responding to standard treatment. It may help doctors choose the best timing to improve survival and recovery in the PICU.
ShanghaiAges 4 weeks–18 years - NCT04184635Recruiting
ECMO for heart-attack shock in the ICU
This trial studies whether using a life-support machine called ECMO (extra support for the heart and lungs) helps people who develop shock right after a heart attack. It aims to improve outcomes when blood flow is failing and organs may be struggling.
ParisAges 18 years+ - NCT04208126Recruiting
Early versus late ECMO start for severe lung failure
This trial compares starting ECMO early versus later in adults with severe lung failure (ARDS). It tests whether starting the life-support machine sooner can improve outcomes by the time doctors need it.
TübingenAges 18 years+ - NCT04445909Recruiting
Continuous skin carbon dioxide monitoring in heart-lung bypass patients
This study checks whether a sensor placed on the skin can reliably measure carbon dioxide levels in people who need VA-ECMO, a kind of temporary heart-lung support. It aims to help doctors monitor breathing and circulation more accurately while you’re on this support.
ViennaAges 18–90 - NCT04709432Recruiting
Study of ECMO care for children in China
This study looks at children (ages 1 day to 18 years) in mainland China who were treated with ECMO during the past 10 years. It aims to understand how ECMO was used and how care outcomes may have differed for children.
Shanghai, Shanghai MunicipalityAges 1 day–18 years - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT06593756Recruiting
Heart-Lung Support and Fluid Response Study
This study watches how your body responds to fluids while on VA ECMO (a heart-lung machine). The goal is to improve care for people needing this support.
ViennaAges 18–75 - NCT06593717Recruiting
Monitoring blood flow in VV-ECMO patients
This study tests how doctors can monitor your blood flow and fluid needs while you are on VV-ECMO. It involves a simple maneuver where your legs are raised to see if your heart needs more fluid.
ViennaAges 18–75 - NCT06814340RecruitingPhase 3
CPAP on ECMO for severe lung failure
This trial is for people with severe lung failure (ARDS) who are already on a life-support machine called VV-ECMO. It tests whether adding a special breathing tube (CPAP) can help their lungs heal better.
BobignyAges 18 years+ - NCT06868823Recruiting
Blood thinners during lung transplant bypass
This study compares two different blood thinners (UFH and LMWH) used during heart-lung bypass (ECMO) for double lung transplant patients. The goal is to see which one works better and is safer.
Prague, Czech RepublicAges 18 years+ - NCT07019662Recruiting
Comparing a new plug device for removing ECMO tubes to standard methods
This trial tests a new suture-based device (Perclose ProStyle) to close the hole where ECMO tubes were placed in the leg, compared to manual pressure or a small surgery. It may help you recover faster with less bleeding after ECMO removal.
FrankfurtAges 18 years+ - NCT07374289Recruiting
CPR and life support before hospital in Ostrava
This trial is testing a way to start CPR and emergency life support (ECPR) at the scene of a cardiac arrest in Ostrava. It might help if you or a loved one has a witnessed cardiac arrest that is likely caused by a heart problem, and you're under 70 years old.
Ostrava, Moravian-Silesian RegionAges 18–70
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Common questions
- Are there clinical trials for ecmo?
- Yes. Clin2 currently lists 72 recruiting ecmo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ecmo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ecmo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.