Clinical trials
ECMO clinical trials
Below are recruiting ecmo clinical trials, each written for real people, not researchers. We’re tracking 72 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05698628Recruiting
Timing strategies to protect legs during peripheral ECMO
This trial studies whether an “early” or more “conservative” approach to improving blood flow to the leg can prevent limb damage during a type of heart-lung machine called peripheral VA-ECMO. It may help reduce the risk of poor leg blood flow (ischemia) in people with severe heart failure-related shock.
SeoulAges 19 years+ - NCT05788120Recruiting
Study heart rhythm problems in adults on VA ECMO
This study looks at how often abnormal heart rhythms happen and how serious they are in adults who are supported with VA ECMO for severe heart failure. It mainly involves using medical information, aiming to better understand complications in this critical situation.
AngersAges 18 years+ - NCT05830721Recruiting
Monitoring leg pressure in adults on life-support
This trial tests a device that continuously measures pressure in an arm or leg to help detect compartment syndrome in people on a heart-lung machine (VA-ECMO). It may help clinicians act sooner if pressure becomes dangerous, potentially reducing complications.
Baltimore, MarylandAges 18 years+ - NCT05913622Recruiting
Testing heart pump unloading during VA ECMO in adults
This study will look at whether “left ventricular unloading” (using a device like IABP or Impella) helps people who are in cardiogenic shock while on VA ECMO. It compares outcomes for people who get unloading versus those who stay on VA ECMO alone.
BrugesAges 18 years+ - NCT06038162Recruiting
Kidney treatment for patients on ECMO
This study compares two ways of giving kidney dialysis to patients who are on a heart-lung bypass machine (ECMO). It aims to find which method works better for filtering the blood.
BordeauxAges 18 years+ - NCT06062212Recruiting
Effects of lung pressure on recovery in severe ARDS on ECMO
This trial looks at how changes in lung pressure during breathing might affect recovery in patients with severe ARDS who are on a heart-lung bypass machine (ECMO). It could help doctors improve treatment for people with this serious lung condition.
Beijing, Beijing MunicipalityAges 18–75 - NCT06118372RecruitingPhase 1
Recombinant vWF concentrate for bleeding on ECMO
This trial tests whether a medication called recombinant von Willebrand factor (vWF) can help control major bleeding in adults who are on life support with ECMO. If you are on ECMO and have a serious bleed, this treatment might help stop the bleeding.
Charlottesville, VirginiaAges 18 years+ - NCT06336655RecruitingPhase 2
Studying heart pump therapy for severe heart shock
This trial tests if unloading the heart during ECMO support helps patients recover better from cardiogenic shock. It compares different ways to reduce the heart's workload.
Salt Lake City, UtahAges 18 years+ - NCT06397417Recruiting
ECMO for refractory cardiac arrest
This study looks at a treatment called ECMO, a machine that does the work of the heart and lungs, to help people whose heart has stopped and does not restart with standard CPR. Researchers want to learn if placing ECMO at the scene can improve survival.
ParisAges 18 years+ - NCT06400797Recruiting
ECMO patient outcomes and quality of life study
This study follows people who are on ECMO (a machine that supports heart and lung function) to see how they do and what their quality of life is like afterward. It helps doctors learn more about long-term recovery.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT06442267RecruitingPhase 4
Comparing blood thinners for ECMO support
This trial compares three different blood thinners (heparin, argatroban, and enoxaparin) used during ECMO support. It aims to find the safest and most effective way to prevent blood clots while on ECMO.
Vienna, State of ViennaAges 18 years+ - NCT06522594RecruitingPhase 2
Beta-blocker medicine for heart recovery on ECMO
This study tests whether a medicine called esmolol (a beta-blocker) can help your heart recover while you are on a heart-lung machine (V-A ECMO). It is for adults with severe heart failure who are already on certain heart medicines.
Rotterdam, South HollandAges 18 years+ - NCT06662084Recruiting
Liver enzyme function in people with cardiogenic shock on heart pumps
This study tests whether your liver’s drug-processing enzymes (CYP) work normally during cardiogenic shock when you are on a heart pump like ECMO or Impella®. The goal is to help doctors choose the right medicines for you.
GenevaAges 18 years+ - NCT06766006Recruiting
Heart-lung machine left ventricle unloading study
This study looks at how to best relieve pressure on the heart while a heart-lung machine is helping to pump blood. It includes anyone who needs this support.
MaastrichtAges 1 day–80 years - NCT06792643RecruitingPhase 2
Cangrelor for heart attack patients on heart-lung support
This trial tests whether adding a fast-acting anti-clotting drug (cangrelor) helps people having a massive heart attack who need a heart-lung machine (VA-ECMO). The goal is to see if it reduces clotting risks without causing dangerous bleeding.
Milan, ItalyAges 18 years+ - NCT06862700Recruiting
Less vasopressors for heart shock on ECMO
This trial is studying whether using less of the medicines that raise blood pressure (vasopressors) can help people with severe heart failure who are on a heart-lung machine (ECMO) survive. It may answer if a gentler approach is safer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06876415Recruiting
Comparing two ways to wean patients off ECMO
This study compares two methods for removing patients from a breathing machine called ECMO. It aims to find which approach works better and is safer.
LyonAges 18 years+ - NCT07009652Recruiting
Optimizing mobile ECMO for sudden cardiac arrest patients
This trial tests a better way to get a mobile team that can start ECMO (a heart-lung machine) to people who have a sudden cardiac arrest outside the hospital. The goal is to see if this approach can help save more lives in certain regions.
Ostrava, Moravian-Silesian RegionAges 3–60 - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT07041086Recruiting
Prehospital ECMO for cardiac arrest
This trial tests whether giving ECMO (a heart-lung machine) to people in cardiac arrest before they reach the hospital can improve survival. It might be an option if you had a witnessed heart attack and received CPR quickly.
Ostrava, Moravian-Silesian RegionAges 18–70 - NCT07113769Recruiting
Biomarkers and platelets in CPR patients
This trial is studying the blood biomarkers and platelet characteristics in patients who receive CPR and are then placed on a heart-lung bypass machine (ECPR). It aims to understand how these biological markers relate to patient outcomes.
Zhengzhou, HenanAges 18 years+ - NCT07193719RecruitingPhase 1/Phase 2
Personalized breathing support for kids after heart surgery
This study tests a personalized breathing technique to improve lung function and heart performance in children who have had heart surgery or are on ECMO. The goal is to find the best way to open up the lungs safely.
BerlinAges birth–18 years - NCT05699005RecruitingPhase 1
Personalized or standard blood transfusion during heart-lung machine
This trial tests whether giving blood in a personalized way, instead of a standard approach, is better for people on a heart-lung bypass machine (VA-ECMO) for heart-related shock. It may help find a safer blood transfusion strategy while you are critically ill.
Lille, NORDAges 18 years+ - NCT07334457Recruiting
Platelet Changes While on ECMO Support
This study looks at how blood cells called platelets change in people who are on a heart-lung machine (ECMO) in the ICU. It aims to better understand how the body responds to this support.
StrasbourgAges 18 years+
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Common questions
- Are there clinical trials for ecmo?
- Yes. Clin2 currently lists 72 recruiting ecmo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ecmo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ecmo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.