Clinical trials
ECMO clinical trials
Below are recruiting ecmo clinical trials, each written for real people, not researchers. We’re tracking 71 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07027202Recruiting
Early heart unloading for severe shock after ECMO
This trial tests a possible treatment to help the heart recover faster in people who need ECMO support for severe cardiogenic shock (when the heart can't pump enough blood). The treatment involves early use of a device to reduce pressure on the heart's main pumping chamber.
Clermont-FerrandAges 18 years+ - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT05814094Recruiting
Testing a red blood transfusion approach during ECMO
This study looks at whether giving red blood cell transfusions in a specific way is practical and safe for people receiving ECMO (a heart-lung support machine). It’s mainly a feasibility study, meaning the goal is to see if the plan can be carried out smoothly and safely.
Camperdown, New South WalesAges 18 years+ - NCT07009652Recruiting
Optimizing mobile ECMO for sudden cardiac arrest patients
This trial tests a better way to get a mobile team that can start ECMO (a heart-lung machine) to people who have a sudden cardiac arrest outside the hospital. The goal is to see if this approach can help save more lives in certain regions.
Ostrava, Moravian-Silesian RegionAges 3–60 - NCT06872021Recruiting
Early balloon pump use after heart-lung bypass
This trial tests if using a heart pump (IABP) early after starting a life support machine (VA-ECMO) helps people recover from cardiogenic shock. It looks for patients whose heart is not pumping well despite support.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06876415Recruiting
Comparing two ways to wean patients off ECMO
This study compares two methods for removing patients from a breathing machine called ECMO. It aims to find which approach works better and is safer.
LyonAges 18 years+ - NCT06062212Recruiting
Effects of lung pressure on recovery in severe ARDS on ECMO
This trial looks at how changes in lung pressure during breathing might affect recovery in patients with severe ARDS who are on a heart-lung bypass machine (ECMO). It could help doctors improve treatment for people with this serious lung condition.
Beijing, Beijing MunicipalityAges 18–75 - NCT06792617Enrolling by invitationEarly Phase 1
Exercise for people on ECMO life support
This study tests if gentle exercise in bed can help people on ECMO (a life-support machine for heart and lungs) get stronger and recover faster. It is for adults in the ICU who are stable enough to move safely.
San Antonio, TexasAges 18 years+ - NCT06776549Recruiting
Cooling or normal temperature after cardiac arrest with ECMO
This trial tests if cooling the body (hypothermia) or keeping normal body temperature (normothermia) after emergency heart-lung support (ECMO) improves survival in adults who had a cardiac arrest outside the hospital.
Kurume, FukuokaAges 18–75 - NCT06770023RecruitingPhase 1
Bridge to lung transplant with ECMO for right heart failure
This study tests a special heart-lung support machine (ECMO) for people waiting for a lung transplant whose heart is failing due to high blood pressure in the lungs. The machine helps rest the heart and lungs until transplant surgery.
Jacksonville, FloridaAges 18–80 - NCT06469801Recruiting
Checking for brain injury in children on ecmo with a portable mri
This study uses a small, portable MRI machine to look for brain injury in children on ECMO (a life-support machine for the heart and lungs). The hope is to spot problems early so they can be treated sooner.
Kansas City, MissouriAges birth–17 years - NCT06397417Recruiting
ECMO for refractory cardiac arrest
This study looks at a treatment called ECMO, a machine that does the work of the heart and lungs, to help people whose heart has stopped and does not restart with standard CPR. Researchers want to learn if placing ECMO at the scene can improve survival.
ParisAges 18 years+ - NCT06336655RecruitingPhase 2
Studying heart pump therapy for severe heart shock
This trial tests if unloading the heart during ECMO support helps patients recover better from cardiogenic shock. It compares different ways to reduce the heart's workload.
Salt Lake City, UtahAges 18 years+ - NCT06276010Recruiting
Nafamostat mesilate for blood thinning in ECMO patients
This trial tests a medicine called nafamostat mesilate to prevent blood clots in patients who need ECMO (a machine that helps your heart and lungs) after heart surgery. It may offer a safer way to thin the blood compared to standard treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06118372RecruitingPhase 1
Recombinant vWF concentrate for bleeding on ECMO
This trial tests whether a medication called recombinant von Willebrand factor (vWF) can help control major bleeding in adults who are on life support with ECMO. If you are on ECMO and have a serious bleed, this treatment might help stop the bleeding.
Charlottesville, VirginiaAges 18 years+ - NCT06038162Recruiting
Kidney treatment for patients on ECMO
This study compares two ways of giving kidney dialysis to patients who are on a heart-lung bypass machine (ECMO). It aims to find which method works better for filtering the blood.
BordeauxAges 18 years+ - NCT05913622Recruiting
Testing heart pump unloading during VA ECMO in adults
This study will look at whether “left ventricular unloading” (using a device like IABP or Impella) helps people who are in cardiogenic shock while on VA ECMO. It compares outcomes for people who get unloading versus those who stay on VA ECMO alone.
BrugesAges 18 years+ - NCT05830721Recruiting
Monitoring leg pressure in adults on life-support
This trial tests a device that continuously measures pressure in an arm or leg to help detect compartment syndrome in people on a heart-lung machine (VA-ECMO). It may help clinicians act sooner if pressure becomes dangerous, potentially reducing complications.
Baltimore, MarylandAges 18 years+ - NCT05788120Recruiting
Study heart rhythm problems in adults on VA ECMO
This study looks at how often abnormal heart rhythms happen and how serious they are in adults who are supported with VA ECMO for severe heart failure. It mainly involves using medical information, aiming to better understand complications in this critical situation.
AngersAges 18 years+ - NCT05699005RecruitingPhase 1
Personalized or standard blood transfusion during heart-lung machine
This trial tests whether giving blood in a personalized way, instead of a standard approach, is better for people on a heart-lung bypass machine (VA-ECMO) for heart-related shock. It may help find a safer blood transfusion strategy while you are critically ill.
Lille, NORDAges 18 years+ - NCT05440851Recruiting
Testing different treatments for severe breathing failure in ICU
This platform trial studies which treatment works best for adults with sudden, severe breathing failure needing oxygen or a breathing machine in the ICU. It may help patients by matching them to the most appropriate treatment strategy and tracking outcomes to improve care.
Tucson, ArizonaAges 18 years+ - NCT03593408Recruiting
Study drug levels in children on ECMO
This study measures how sedating and pain medicines move through the body in children who are supported by ECMO (a heart-lung machine). It may help doctors choose safer and more effective dosing for sedation and pain control during ECMO.
Boston, MassachusettsAges birth–17 years - NCT04273607RecruitingPhase 2/Phase 3
Test an ECMO approach without blood thinners for lung failure
This trial studies whether people on a breathing machine called VV-ECMO can be managed without routine blood thinners, to reduce bleeding risk. It is meant for adults with severe lung failure (ARDS) and checks that it is safe for you to avoid anticoagulation.
Toronto, OntarioAges 18 years+
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Common questions
- Are there clinical trials for ecmo?
- Yes. Clin2 currently lists 71 recruiting ecmo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ecmo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ecmo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.