Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,830 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05923905RecruitingPhase 4
Study of FB1006 for people with early ALS
This trial tests whether FB1006 is safe and works better than usual care for treating amyotrophic lateral sclerosis (ALS). It focuses on people with relatively early ALS and good breathing function.
Beijing, Beijing MunicipalityAges 18–80 - NCT05924100RecruitingPhase 2
Luspatercept for lower red blood counts in MDS with del5q
This Phase 2 trial studies luspatercept to improve anemia (low red blood cells) in people with MDS that has a del5q change. It also checks safety, especially for people who need red blood cell transfusions and have not benefited from prior standard treatments.
AlessandriaAges 18 years+ - NCT05926505RecruitingPhase 2/Phase 3
Anakinra for lingering symptoms after COVID-19
This Phase 2/3 trial studies whether anakinra can improve ongoing (post-acute) COVID-19 symptoms lasting for more than two months. It mainly looks for better safety and symptom improvement in people with specific inflammation and lung-related findings.
JenaAges 18 years+ - NCT05926700RecruitingPhase 2
Testing cadonilimab plus anlotinib for advanced soft tissue sarcoma
This Phase 2 study tests two medicines (cadonilimab and anlotinib) in people with advanced soft tissue sarcoma whose cancer grew after standard first treatment. It aims to see whether the combination can shrink tumors and improve safety.
HangzhouAges 18 years+ - NCT05930093Recruiting
Test LivPhcD capsules for fatty liver disease safety
This trial studies whether LivPhcD capsules can improve fatty liver disease and checks for side effects. It may help people with non-alcohol-related fatty liver disease who meet specific liver-scanning and lab results.
Taipei, Not Required For This CountryAges 20–75 - NCT05930860Recruiting
Endoscopic treatment for certain superficial stomach growths
This trial studies how safe and effective a procedure called endoscopic submucosal dissection (ESD) is for treating certain early, superficial stomach (gastric) growths. It may be an option if your growth fits the endoscopy criteria and you are not a good candidate for stomach surgery.
RomeAges 18 years+ - NCT05933720Recruiting
Study drug peptides for blocked leg artery disease
This study tests how well a drug called Slavinorm® (regulatory polypeptides) works and is safe for adults with blocked arteries in the legs due to atherosclerosis. You might be considered if you have confirmed leg artery blockage and can safely do a treadmill walking test.
RyazanAges 18–80 - NCT05934383Recruiting
Ultrasound treatment to lower blood pressure after kidney transplant
This trial tests whether ultrasound “renal denervation” can safely and effectively lower blood pressure in people whose hypertension is not well controlled after a kidney transplant. If you qualify, the study may help you see whether this procedure reduces office and 24-hour blood pressure readings without harming your transplanted kidney.
RotterdamAges 18 years+ - NCT05935215RecruitingPhase 3
Switch from anti-C5 shots to iptacopan for aHUS
This trial tests whether people with atypical hemolytic uremic syndrome (aHUS) who are doing well on anti-C5 treatment can safely switch to iptacopan. It focuses on both effectiveness (blood counts and kidney function) and safety after the switch.
Nanjing, JiangsuAges 18–100 - NCT05938712RecruitingPhase 2
Kidney transplant trial using two diabetes medicines safely
This Phase 2 trial tests whether combining two diabetes medicines—an SGLT2 tablet and a GLP-1 shot (semaglutide)—can improve kidney outcomes and safety in people with a kidney transplant. It may help some recipients, but it also carefully checks for infection risk, diabetes complications, and pregnancy plans.
Toronto, OntarioAges 18 years+ - NCT05939661RecruitingPhase 2
Total treatment before surgery for early rectal cancer
This Phase 2 study tests a “total neoadjuvant” approach, meaning you receive cancer treatment before surgery, to improve safety and effectiveness for rectal cancer. It may help by shrinking the tumor and planning a more effective operation, while researchers carefully track side effects.
OsakaAges 18 years+ - NCT05942339Recruiting
Testing ARC-IM lumbar therapy to help walking after spinal cord injury
This study tests a therapy using an implanted spinal array and a lumbar system (ARC-IM) to support mobility in people with chronic spinal cord injury. It focuses on whether the approach is safe and may improve walking or movement over time.
Lausanne, Canton of VaudAges 18–65 - NCT05947669RecruitingPhase 3
Infliximab for diarrhea or colitis from immune cancer therapy
This trial studies whether infliximab can treat stomach inflammation in the colon (colitis) or frequent diarrhea caused by immune checkpoint cancer drugs. It aims to improve symptoms safely for adults with certain solid cancers.
AalborgAges 18 years+ - NCT05955326RecruitingPhase 4
Testing a stroke drug to improve recovery after ischemic stroke
This trial tests whether sovateltide is safe and can improve recovery in people with an acute ischemic stroke. It focuses on patients who start the study drug within 24 hours of symptom onset and do not have bleeding in the brain.
Guntur, Andhra PradeshAges 18–78 - NCT05959694RecruitingPhase 1/Phase 2
Study drug TQB3909 for CLL/SLL that keeps coming back
This trial tests TQB3909 tablets in people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that has returned or did not respond to prior treatment. The goal is to see if the drug is safe and can shrink the cancer or improve control of the disease.
Anqing, AnhuiAges 18–75 - NCT05962840RecruitingPhase 4
Rituximab plus telitacicept for ANCA vasculitis
This Phase 4 trial studies whether rituximab combined with telitacicept works better and is safe for people with severe active ANCA-associated vasculitis (including certain subtypes like GPA or MPA). If you meet specific blood test and disease activity criteria, you may be considered to help lower inflammation and prevent flare-ups.
BeijingAges 18–65 - NCT05965284RecruitingPhase 4
Telitacicept to help keep ANCA vasculitis in remission
This trial studies telitacicept to see if it can help keep ANCA-associated vasculitis in remission after initial treatment with steroids and rituximab. It may help prevent future flare-ups, while closely watching for side effects.
Beijing, Beijing MunicipalityAges 18–65 - NCT05968326RecruitingPhase 2
Chemo plus new vaccines versus chemo alone after pancreatic surgery
This Phase 2 trial tests whether adding two study medicines (an immune-based vaccine treatment plus atezolizumab) to standard chemo helps prevent pancreatic cancer from coming back after surgery. It compares the combination against standard chemo alone, looking at safety and how well it prevents relapse.
Los Angeles, CaliforniaAges 18 years+ - NCT05968768RecruitingPhase 2
Naxitamab trial for children with treatment-resistant Ewing sarcoma
This Phase 2 trial studies naxitamab (a targeted antibody) in children and young adults whose Ewing sarcoma has come back or kept growing despite prior treatment. You may be eligible if the tumor shows a target called GD2 and if your heart, lungs, and past treatment recovery meet safety requirements.
Warsaw, MazowianAges 2–21 - NCT05970237Recruiting
Dapagliflozin for type 2 diabetes with high blood pressure
This trial studies whether dapagliflozin (the medicine in Trudapa tabs) is safe and works in people who have both type 2 diabetes and high blood pressure. It may help control blood sugar and blood pressure, while researchers closely watch for side effects.
Incheon, Namdong-guAges 19 years+ - NCT05979051RecruitingPhase 2/Phase 3
Study of SHR-1703 for eosinophilic granulomatosis with polyangiitis (EGPA)
This trial tests a new medicine called SHR-1703 for people with EGPA that has come back or is hard to treat. It aims to see if the drug can help control the disease better.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05983783RecruitingPhase 3
Testing two drug combinations for advanced prostate cancer
This trial compares two combinations of drugs for men with metastatic hormone-sensitive prostate cancer that has a high tumor burden. One group gets rezvilutamide plus hormone therapy and chemotherapy, while the other gets rezvilutamide plus hormone therapy alone. The goal is to see which is more effective and safe.
Nanjing, JiangsuAges 40–80 - NCT05984147RecruitingPhase 1
Study of oral drug AUR108 for advanced lymphoma
This trial tests an experimental oral drug called AUR108 for people with advanced lymphoma that has come back after at least two prior treatments. The goal is to see if the drug is safe and if it can help shrink or control the lymphoma.
Visakhapatnam, Andhra PradeshAges 18–99 - NCT05990556Recruiting
Blocking blood supply to glioblastoma: safety and benefit
This study tests whether blocking the blood supply to a brain tumor (glioblastoma) can help treat it safely. It is for people who have just been diagnosed and have not had any treatment yet.
Guangzhou, GuangdongAges 18–70
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,830 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.