Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,733 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06952478RecruitingPhase 3
Comparing a new injectable multiple myeloma drug to Darzalex Faspro
This trial compares a new injectable medicine (CT-P44) to an approved one (Darzalex Faspro), both given with lenalidomide and dexamethasone, for people whose multiple myeloma has come back or stopped responding to treatment. It aims to see if the new option works just as well.
Taipei, Beitou DistrictAges 18 years+ - NCT06947291RecruitingPhase 2
Study of glumetinib plus nab-docetaxel for advanced stomach cancer
This trial tests a combination of two drugs, glumetinib and nab-docetaxel, in people with advanced stomach cancer or other solid tumors that have a specific change in the MET gene. The goal is to see if this combination is safe and works better than current treatments.
Hangzhou, ZhejiangAges 18 years+ - NCT06947941RecruitingPhase 3
Testing karxt for psychosis in alzheimer's disease
This study tests whether a new medicine called KarXT can help with psychosis (hallucinations or delusions) in people with Alzheimer's disease. It aims to reduce troubling symptoms while being safe for older adults.
Gilbert, ArizonaAges 55–90 - NCT06951698RecruitingPhase 3
Testing KarXT for bipolar I mania
This trial tests a new medicine, KarXT, to see if it can safely treat manic episodes in people with bipolar I disorder. It is for patients who are currently hospitalized for a manic episode that started within the last 3 weeks.
Bentonville, ArkansasAges 18–65 - NCT06947993RecruitingPhase 2
Study of a new treatment for moderate to severe eczema
This study tests an experimental treatment for people with moderate to severe eczema that has lasted at least a year. It aims to see if the new medicine can help control symptoms better than current options.
Birmingham, AlabamaAges 18–100 - NCT06321341RecruitingPhase 4
Testing Vespireit for chronic dizziness from autonomic dysfunction
This trial tests a new medication called Vespireit (prolonged-release buspirone) for people with chronic dizziness caused by a problem with the autonomic nervous system. The study aims to see if the drug helps reduce dizziness and improve quality of life.
BryanskAges 18–65 - NCT06305663Recruiting
Contact lens to slow myopia in children
This study tests a special contact lens designed to slow the progression of nearsightedness (myopia) in children ages 8 to 12. If your child is nearsighted and needs glasses, this lens might help reduce the need for stronger prescriptions over time.
Beijing, Beijing MunicipalityAges 8–12 - NCT06937944RecruitingPhase 3
New Botox-like injection for frown lines
This study tests a new botulinum toxin injection (similar to Botox) to see how well it smooths moderate to severe frown lines between the eyebrows. The treatment is given as a single injection and may help soften those lines for several months.
Beijing, Beijing MunicipalityAges 18–65 - NCT06940336RecruitingPhase 4
Testing tafamidis for transthyretin amyloid polyneuropathy
This trial tests whether the drug tafamidis can help people with a specific type of nerve damage caused by abnormal protein buildup. It aims to slow or improve symptoms in adults with this condition.
JinanAges 18–80 - NCT06940739RecruitingPhase 1/Phase 2
IOV-3001 and lifileucel for advanced melanoma
This trial tests a new combination treatment, IOV-3001 and lifileucel, for people with advanced melanoma that has not responded to standard immunotherapy and cannot be surgically removed. It aims to see if this cellular therapy is safe and effective.
Denver, ColoradoAges 18–70 - NCT06937229RecruitingPhase 3
Long-term study of KarXT for agitation in Alzheimer's
This trial tests if KarXT, taken with KarX-EC, is safe and effective for long-term treatment of agitation in Alzheimer's disease. It is for people who already completed a previous KarXT study.
Chandler, ArizonaAges 55–90 - NCT06938347RecruitingPhase 3
New contrast agent for heart ultrasound to detect shunts
This trial tests a new contrast agent (ASI-02) compared to a standard saline solution for people who need a heart ultrasound to detect a right-to-left shunt. It may help provide clearer images so doctors can make a better diagnosis.
Chicago, IllinoisAges 18 years+ - NCT06932263RecruitingPhase 2
Study of a new asthma medicine for uncontrolled asthma
This study tests a new medicine called tozorakimab for adults whose asthma is not well controlled despite using their usual inhalers. It aims to see if it can reduce asthma attacks and improve symptoms.
Bakersfield, CaliforniaAges 18–75 - NCT06931990RecruitingPhase 1/Phase 2
Testing a new tablet for eczema in Chinese adults
This trial tests an experimental tablet (LT-002-158) for adults with moderate-to-severe eczema that hasn't improved enough with standard creams. The goal is to see if the tablet is safe and helps control symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT06932003RecruitingPhase 1/Phase 2
Testing a new tablet for hidradenitis suppurativa
This trial is testing an experimental tablet called LT-002-158 in adults with moderate to severe hidradenitis suppurativa (HS) that hasn't improved enough with standard treatments. The goal is to see if it's safe and helps reduce painful lumps and abscesses.
Beijing, Beijing MunicipalityAges 18–75 - NCT06933992Enrolling by invitation
Chocolate balloon for blocked leg arteries
This trial tests a special balloon called the Chocolate Balloon Catheter to open blocked leg arteries. It may help people with peripheral artery disease avoid more invasive surgery.
HangzhouAges 18–80 - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65 - NCT06936488Enrolling by invitation
Study of Ivonescimab with TAS-102 for advanced colorectal cancer
This trial tests a combination of two drugs – ivonescimab (a type of immunotherapy) and TAS-102 (a chemotherapy) – for people with advanced colorectal cancer that has not responded to at least two prior chemotherapies. The goal is to see if this new combo can shrink tumors or slow cancer growth.
Huai'an, JiangsuAges 18–75 - NCT06383247Recruiting
Precision TMS for parkinson's motor symptoms
This trial tests a precise form of brain stimulation (called TMS) to see if it can improve movement problems like stiffness, slowness, or tremors in people with Parkinson's disease. Participants must have a stable medication routine and no metal implants or brain surgery history.
Hefei, AnhuiAges 40 years+ - NCT06931483Enrolling by invitation
Brain stimulation for Parkinson's motor symptoms
This trial uses a new type of non-invasive brain stimulation to target a deep brain area that controls movement. It aims to improve motor symptoms like stiffness and slowness in people with Parkinson's disease, without needing surgery.
Hefei, AnhuiAges 50–80 - NCT06931457Recruiting
Radiofrequency with platelet injection for nerve pain in the throat
This study tests if combining pulsed radiofrequency (a treatment that uses heat to calm nerve pain) with a platelet injection (using your own blood to help healing) is safe and works better for treating throat nerve pain (glossopharyngeal neuralgia) than radiofrequency alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06924658RecruitingPhase 2
Metformin for gout patients study
This trial tests if metformin, a common diabetes drug, can help people with gout. It aims to see if the drug is safe and effective for reducing gout symptoms.
TantaAges 18–60 - NCT06928519Recruiting
Entacapone with Madopar for early Parkinson's
This study tests whether adding entacapone to Madopar (a common Parkinson's medication) safely improves symptoms in people with early-stage Parkinson's. It aims to see if the combination works better than Madopar alone.
Nanning, GuanxiAges 18–80 - NCT06928090Enrolling by invitation
HIV trial testing two-med combo for first-time treatment
This trial studies a two-drug pill (DTG/3TC) for people who have never taken HIV medication before. It aims to see if this simpler treatment is effective and safe for controlling HIV-1.
DaejeonAges 19 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,733 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.