Clinical trials
Epilepsy; Seizure clinical trials
Below are recruiting epilepsy; seizure clinical trials, each written for real people, not researchers. We’re tracking 54 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06275685Recruiting
Forecasting seizures with a smart wearable
This study tests if a smart wristband called EmbracePlus can predict seizures. You wear the device and track your seizures to see if it can warn you ahead of time.
Boston, MassachusettsAges 6 years+ - NCT07116330Recruiting
Seizures starting after 50: testing heart and blood vessel risk
This study looks at whether checking and treating heart and blood vessel risk factors can help people who start having seizures after age 50. It includes two parts: one that adds a risk check to your regular care, and one that uses your medical records to learn more about this condition.
BoråsAges 50 years+ - NCT06466681Recruiting
Attention changes after a seizure in epilepsy
This study looks at how attention and concentration change right after a seizure in people with epilepsy. It uses a short hospital stay to track these changes, which may help improve understanding and future treatment.
LilleAges 18–80 - NCT06908356RecruitingPhase 2
Testing PRAX-628 for focal or tonic-clonic seizures
This study tests an experimental pill called PRAX-628 for adults whose seizures are not fully controlled by current medications. It aims to see if the drug is safe and effective at reducing seizures.
Phoenix, ArizonaAges 18–75 - NCT04144439RecruitingPhase 4
GABA treatment for ADHD and seizures in children with epilepsy
This trial studies whether adding GABA (a substance that affects brain signaling) can help children who have both epilepsy (seizures) and ADHD. If it works, it may reduce symptoms related to either seizures, ADHD, or both.
TantaAges 4–18 - NCT07663240Enrolling by invitation
Program to help women with epilepsy reduce ER visits
This study is for Black or Hispanic women with epilepsy who often go to the emergency room for seizures. It aims to help reduce ER visits by connecting you with better follow-up care and support.
Atlanta, GeorgiaAges 18 years+ - NCT05718817Enrolling by invitationPhase 3
Long-term study of XEN1101 for people with epilepsy
This study gives XEN1101 in an open-label way (everyone knows they’re getting the drug) to people who finished earlier epilepsy studies. It aims to see how the treatment continues to work and whether it’s safe over the long term.
Phoenix, ArizonaAges 12 years+ - NCT07234695RecruitingPhase 3
Levetiracetam to prevent seizures in adults with Down syndrome and Alzheimer's
This trial tests if levetiracetam, a seizure medication, can prevent seizures in adults with Down syndrome who also have Alzheimer's disease. It aims to help manage a common complication and improve quality of life.
Granada, AndalusiaAges 40 years+ - NCT04715646RecruitingPhase 3
Brivaracetam study for children with hard-to-control seizures
This trial looks at how safe brivaracetam is and how well it can be used in children and teens with certain types of epilepsy that are not well controlled. It may help families who are dealing with frequent focal seizures despite taking seizure medicines.
Hawthorne, New YorkAges 1 month+ - NCT05594017RecruitingEarly Phase 1
Test medicine to change brain rhythms and study memory
This early research study tests whether a medicine can change the brain’s electrical “rhythms” while people do memory-related tasks. It may help researchers understand how brain timing affects memory in people who are already being evaluated with specialized brain electrode monitoring.
Dallas, TexasAges 18–55 - NCT05865561Recruiting
Breath and skin tests to predict epileptic seizures
This study looks for specific chemicals in a person’s breath or skin (volatile organic compounds) that might help predict seizures. It’s mainly for adults with drug-resistant epilepsy who will undergo at least 48 hours of video EEG monitoring.
ParisAges 18 years+ - NCT06027749Recruiting
Long-term home EEG monitoring for people with seizures
This study is testing a wearable EEG device that you can use at home for up to 30 days. It records brain activity to help doctors better understand your seizures. The goal is to see if this longer monitoring can capture more seizure events than standard short-term EEG tests.
Tampa, FloridaAges 18–70 - NCT06278428Recruiting
Epilepsy in Infants: Genes and Disease Course
This study looks at children with severe epilepsy that starts before age 2. It aims to understand how different gene changes affect the disease and how it progresses over time.
Ho Chi Minh CityAges Up to 1.9 years - NCT06383689Recruiting
Improving comfort during epilepsy monitoring
This study tests if changing how we give placebo pills during long hospital monitoring can make the experience better and less stressful for people with epilepsy. The goal is to improve care for those who need this test before epilepsy surgery.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06579573RecruitingPhase 3
Testing a new drug for generalized tonic-clonic seizures in Japan
This study tests a new medicine (ONO-2017) for people with a type of epilepsy that causes whole-body seizures. It looks at whether adding this drug to your current seizure medicines can reduce how often those seizures happen.
AichiAges 12 years+ - NCT06590896RecruitingPhase 2
Safety of cenobamate for Japanese adults with partial seizures
This trial studies the safety of cenobamate for Japanese people who have partial onset seizures and have already finished a previous study of the same drug. It helps doctors learn more about long-term safety.
EhimeAges Any age - NCT06617845Recruiting
Optimizing brain stimulation for epilepsy
This study aims to find the best settings for brain stimulation devices already implanted in patients with epilepsy. It may help improve seizure control by adjusting how the device works.
Rochester, MinnesotaAges 6 years+ - NCT07329257Recruiting
Project PENGUIN: Study of rare brain development disorders
This study looks at rare and ultra-rare conditions that affect brain development. It aims to learn more about what causes these conditions. You may join if you or your child have a diagnosed or suspected neurogenetic disorder.
Columbia, MissouriAges Up to 99 years - NCT02216500Recruiting
Study ketogenic diet effects in people with epilepsy
This study looks at how a high-fat, low-carbohydrate ketogenic diet may change electrical activity in the brain and related body measurements in people with epilepsy. You may be asked to follow the diet and keep records so the researchers can compare changes over time.
Gainesville, FloridaAges Up to 50 years - NCT07445074Recruiting
AI phone app to help teens and young adults with epilepsy take their medicine
This study tests a mobile app that uses artificial intelligence to help people with epilepsy remember to take their anti-seizure medication. It is for teens and young adults (ages 14-24) living in Florida who are from underserved communities.
Orlando, FloridaAges 14–24 - NCT05289934Recruiting
Recorded music to see how it affects seizures
This study is testing whether listening to recorded music can change seizure activity and brain-wave patterns in children monitored in an epilepsy center. Your child might benefit by helping researchers learn how music could affect seizures during close observation.
Baltimore, MarylandAges 4–17 - NCT05140265Recruiting
Uses EEG and medical records to build a privacy-protected database
This study creates a large, de-identified database by combining EEG test recordings with basic clinical information from medical records. It helps researchers use brain-wave data for future research while protecting your identity.
Albuquerque, New MexicoAges 18 years+ - NCT06388161Recruiting
Autoantibody study in new focal seizures
This research study looks for specific immune system markers (autoantibodies) in the blood and spinal fluid of people who have recently started having focal seizures (seizures that start in one part of the brain) with no known cause. Finding these markers could help doctors understand why the seizures started.
Hangzhou, ZhejiangAges 14–100 - NCT07226908Enrolling by invitation
Brain electrode study for epilepsy and memory
This study places electrodes in the brain to learn how seizures spread and how memory works. It may help people with temporal lobe epilepsy understand their condition better and improve future treatments.
Stanford, CaliforniaAges 18–65
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Common questions
- Are there clinical trials for epilepsy; seizure?
- Yes. Clin2 currently lists 54 recruiting epilepsy; seizure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy; seizure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy; seizure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.