Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 325 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06555965Recruiting
STXBP1 and SYNGAP1 natural history study
This study follows people with STXBP1 or SYNGAP1 gene changes over time to learn more about how these conditions affect the body and mind. It does not test a treatment but helps researchers understand the natural course of the disorder.
Palo Alto, CaliforniaAges Any age - NCT06551090Recruiting
Anxiety and memory study for temporal lobe epilepsy patients
This research study looks at how anxiety and memory work in people with temporal lobe epilepsy. It uses brain recordings to better understand these conditions, which might lead to better treatments in the future.
New York, New YorkAges 18–55 - NCT06309251Recruiting
Ketogenic diet for children with epilepsy or other conditions
This trial studies how well a ketogenic diet works for children with hard-to-treat epilepsy or certain other diseases. It aims to see if the diet improves quality of life.
Milan, MIAges Up to 18 years - NCT06545643Recruiting
Sleep-sensitive seizure risk test with wearable EEG
This study uses a comfortable headband to track your sleep and brain activity. It may help better understand when seizures are likely to happen.
Durham, North CarolinaAges 18 years+ - NCT06489561Enrolling by invitation
Brain activity study for epilepsy patients
This study looks at how your brain makes decisions. It involves pressing buttons on a laptop while your brain activity is recorded. The goal is to understand how the brain works in people with epilepsy.
Los Angeles, CaliforniaAges 18–65 - NCT06443463Enrolling by invitationPhase 2
Long-term safety of BHV-7000 in epilepsy
This study checks the long-term safety of BHV-7000 for people who already completed an earlier trial with this drug. You keep taking the same medicine while doctors watch for any side effects over time.
Birmingham, AlabamaAges 18–75 - NCT06455384Recruiting
Studying a digital tool for genetic testing services
This trial tests a new online tool called the Genetics Navigator, which helps people access genetic testing services more easily. If you or your child have been referred for genetic testing at Mount Sinai Hospital or SickKids in Toronto, this study may help you manage the process online.
Toronto, OntarioAges 18 years+ - NCT06453759Recruiting
Brain recordings during SEEG in children
This study takes extra recordings from the brain during a routine SEEG procedure in children with epilepsy to learn more about how the brain works. It may help improve future epilepsy surgeries.
LondonAges 2–20 - NCT06399952Recruiting
Natural history study for Baker Gordon syndrome
This study follows people with Baker Gordon syndrome over time to better understand the condition. Participants and their caregivers share medical records and complete tests and questionnaires.
Columbia, MissouriAges birth–99 years - NCT06391294Enrolling by invitation
Brain stimulation study for language mapping during awake surgery
This study uses gentle electrical stimulation on the brain during awake surgery to understand how language works. It's for people having brain tumor removal or epilepsy monitoring who can speak English and do not have serious speech or thinking problems.
Chicago, IllinoisAges 18–80 - NCT05327387Recruiting
Brain stimulation study using implanted electrodes
This study tests a model-based way of using electrical brain stimulation in people who are having surgery for drug-resistant epilepsy or brain tumors. It uses implanted electrodes to measure brain activity and may help improve how stimulation is planned during surgical care.
Los Angeles, CaliforniaAges 18 years+ - NCT06292299Recruiting
Breathing monitor study for children with sleep or breathing issues
This study looks at how well a new breathing monitor works for children with sleep problems, breathing pauses in newborns, or epilepsy. It may help doctors better understand breathing patterns without extra needles or blood tests.
Glasgow, Glasgow CityAges 1 minute–16 years - NCT06252532Enrolling by invitation
Brain wave study for epilepsy with electrodes
This research study looks at how certain brain waves (called theta oscillations) help you focus and prioritize information. If you have epilepsy that hasn't been controlled with medicines and you already have brain electrodes in place for your epilepsy monitoring, you may be able to join this study to help scientists understand the role of these brain signals.
Chapel Hill, North CarolinaAges 18–80 - NCT06213090Recruiting
Study on patterns of neurodevelopmental disorders
This study looks at patterns of brain development issues in children who visit a specific medical center. It may help doctors understand these conditions better.
Phoenix, ArizonaAges Any age - NCT06144957Enrolling by invitation
SLC13A5 deficiency natural history study (US only)
This study follows people with SLC13A5 deficiency (a rare genetic condition that affects brain development) to learn more about the disease over time. It collects health information, assessments, and samples to help understand the condition and plan future treatments.
Palo Alto, CaliforniaAges Any age - NCT06138808Enrolling by invitation
5-sense score validation for epilepsy surgery
This study is for people with epilepsy who are being considered for brain surgery but cannot have a direct surgical approach. It tests a new scoring method (5-SENSE) that uses non-invasive tests like MRI and EEG to see if it can help doctors make better surgery decisions.
Gainesville, FloridaAges 15 years+ - NCT05418894Recruiting
Study brain signals and improve treatment-resistant depression
This trial studies how brain activity relates to feelings and depression, using brain electrodes to measure signals. It’s meant for people with long-lasting, treatment-resistant major depression who may need stimulation while continuing psychiatric care.
Houston, TexasAges 22–70 - NCT06059157Recruiting
Brain mapping with advanced MRI for epilepsy surgery
This trial uses special MRI scans to create a detailed map of the brain areas causing seizures, helping doctors plan SEEG surgery. It's for people with hard-to-control epilepsy who are already scheduled for SEEG.
BrusselsAges 3 years+ - NCT06038929Recruiting
Vagus nerve stimulation and stomach function study
This study looks at how vagus nerve stimulation (VNS) affects how your stomach works, like emptying and stretching. It may help researchers understand the digestive side effects of VNS in people who already have a VNS device for epilepsy or depression.
Minneapolis, MinnesotaAges 18 years+ - NCT06019182Recruiting
MEHMO syndrome: Understanding the condition over time
This study follows people with or at risk for MEHMO syndrome over time to better understand the condition and identify biological markers. It may include both affected individuals and their family members to see how the condition runs in families.
Bethesda, MarylandAges 1 week–100 years - NCT06016686RecruitingPhase 1
Recording nerve signals from the vagus nerve in awake humans
This study tests a new way to listen to the vagus nerve in awake people. It may help understand how the nerve controls body functions like heart rate and digestion.
Minneapolis, MinnesotaAges 18–40 - NCT05989893Recruiting
Mapping human thinking during brain surgery
This study maps how thinking works in people with epilepsy or brain lesions near important brain areas. It involves testing during brain surgery procedures to help researchers understand healthy brain function.
Houston, TexasAges 18–75 - NCT05996900Recruiting
Brain stimulation study for adults with epilepsy
This study uses advanced brain monitoring and noninvasive magnetic stimulation to understand how repetitive brain stimulation works in people with epilepsy who are already scheduled for hospital monitoring. It may help develop better treatments for seizures.
Stanford, CaliforniaAges 18–65 - NCT05854160Recruiting
Brain stimulation study during epilepsy surgery evaluation
This trial studies how stimulating the brain changes communication between parts of the brain involved in emotion and memory. You may be able to join if you are already having epilepsy surgery and doctors will place specific brain electrodes as part of your evaluation.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 325 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.