Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 339 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05871372Recruiting
Study brain circuits behind mood using brain monitoring
This study looks at how brain networks relate to mood and depression by recording brain activity during specific procedures. You may be able to join if you’re already having brain monitoring for epilepsy or are part of a depression deep brain stimulation program.
Houston, TexasAges 21–70 - NCT05981755Recruiting
Breathing rescue to prevent SUDEP in epilepsy
This trial tests a breathing rescue device to prevent SUDEP (sudden unexpected death in epilepsy) in people with hard-to-control focal epilepsy who are staying in the hospital for invasive brain monitoring.
Houston, TexasAges 18 years+ - NCT05996900Recruiting
Brain stimulation study for adults with epilepsy
This study uses advanced brain monitoring and noninvasive magnetic stimulation to understand how repetitive brain stimulation works in people with epilepsy who are already scheduled for hospital monitoring. It may help develop better treatments for seizures.
Stanford, CaliforniaAges 18–65 - NCT06016686RecruitingPhase 1
Recording nerve signals from the vagus nerve in awake humans
This study tests a new way to listen to the vagus nerve in awake people. It may help understand how the nerve controls body functions like heart rate and digestion.
Minneapolis, MinnesotaAges 18–40 - NCT06019182Recruiting
MEHMO syndrome: Understanding the condition over time
This study follows people with or at risk for MEHMO syndrome over time to better understand the condition and identify biological markers. It may include both affected individuals and their family members to see how the condition runs in families.
Bethesda, MarylandAges 1 week–100 years - NCT06027749Recruiting
Long-term home EEG monitoring for people with seizures
This study is testing a wearable EEG device that you can use at home for up to 30 days. It records brain activity to help doctors better understand your seizures. The goal is to see if this longer monitoring can capture more seizure events than standard short-term EEG tests.
Tampa, FloridaAges 18–70 - NCT06038929Recruiting
Vagus nerve stimulation and stomach function study
This study looks at how vagus nerve stimulation (VNS) affects how your stomach works, like emptying and stretching. It may help researchers understand the digestive side effects of VNS in people who already have a VNS device for epilepsy or depression.
Minneapolis, MinnesotaAges 18 years+ - NCT06059157Recruiting
Brain mapping with advanced MRI for epilepsy surgery
This trial uses special MRI scans to create a detailed map of the brain areas causing seizures, helping doctors plan SEEG surgery. It's for people with hard-to-control epilepsy who are already scheduled for SEEG.
BrusselsAges 3 years+ - NCT06065852Recruiting
National registry for rare kidney diseases
This study creates a registry to collect health information from people with rare kidney diseases. It aims to improve understanding and future treatments by tracking patient experiences.
Bristol, South WestAges Any age - NCT06092125Recruiting
Brain disease imaging study with PET/MR scans
This trial uses advanced PET and MR scans to better understand and diagnose brain diseases like Alzheimer's, Parkinson's, epilepsy, and brain tumors. It may help identify new ways to track these conditions.
Beijing, Beijing MunicipalityAges 18–60 - NCT06202976Recruiting
Mapping epilepsy networks with brain imaging
This trial uses advanced brain imaging to map the networks causing seizures in children with certain types of epilepsy. The goal is to better understand where seizures start so doctors can plan more targeted treatments.
ParisAges Up to 18 years - NCT06213090Recruiting
Study on patterns of neurodevelopmental disorders
This study looks at patterns of brain development issues in children who visit a specific medical center. It may help doctors understand these conditions better.
Phoenix, ArizonaAges Any age - NCT06241924Recruiting
Brain wave study in Parkinson's and epilepsy
This study looks at brain wave activity in areas that control movement, both in people with Parkinson's disease who already have deep brain stimulation electrodes and in people with epilepsy who are undergoing brain monitoring with stereo-EEG. The goal is to understand how brain signals change during normal movement and in movement problems, which may help improve treatments.
BordeauxAges 18–75 - NCT06278428Recruiting
Epilepsy in Infants: Genes and Disease Course
This study looks at children with severe epilepsy that starts before age 2. It aims to understand how different gene changes affect the disease and how it progresses over time.
Ho Chi Minh CityAges Up to 1.9 years - NCT06292299Recruiting
Breathing monitor study for children with sleep or breathing issues
This study looks at how well a new breathing monitor works for children with sleep problems, breathing pauses in newborns, or epilepsy. It may help doctors better understand breathing patterns without extra needles or blood tests.
Glasgow, Glasgow CityAges 1 minute–16 years - NCT06309251Recruiting
Ketogenic diet for children with epilepsy or other conditions
This trial studies how well a ketogenic diet works for children with hard-to-treat epilepsy or certain other diseases. It aims to see if the diet improves quality of life.
Milan, MIAges Up to 18 years - NCT06455384Recruiting
Studying a digital tool for genetic testing services
This trial tests a new online tool called the Genetics Navigator, which helps people access genetic testing services more easily. If you or your child have been referred for genetic testing at Mount Sinai Hospital or SickKids in Toronto, this study may help you manage the process online.
Toronto, OntarioAges 18 years+ - NCT06383689Recruiting
Improving comfort during epilepsy monitoring
This study tests if changing how we give placebo pills during long hospital monitoring can make the experience better and less stressful for people with epilepsy. The goal is to improve care for those who need this test before epilepsy surgery.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06388161Recruiting
Autoantibody study in new focal seizures
This research study looks for specific immune system markers (autoantibodies) in the blood and spinal fluid of people who have recently started having focal seizures (seizures that start in one part of the brain) with no known cause. Finding these markers could help doctors understand why the seizures started.
Hangzhou, ZhejiangAges 14–100 - NCT06399952Recruiting
Natural history study for Baker Gordon syndrome
This study follows people with Baker Gordon syndrome over time to better understand the condition. Participants and their caregivers share medical records and complete tests and questionnaires.
Columbia, MissouriAges birth–99 years - NCT06432907Recruiting
Brain signal study during movement in epilepsy patients
This study records brain signals from electrodes already placed in your brain for medical reasons. It looks at how your brain controls movement, which could help develop future devices for people with paralysis.
MoscowAges 18–70 - NCT06453759Recruiting
Brain recordings during SEEG in children
This study takes extra recordings from the brain during a routine SEEG procedure in children with epilepsy to learn more about how the brain works. It may help improve future epilepsy surgeries.
LondonAges 2–20 - NCT06498362Recruiting
Levetiracetam for Seizure Emergencies in Children
This study looks back at children who had a prolonged seizure (status epilepticus) and needed a second medicine after the first one didn't work. Doctors want to see how well levetiracetam works compared to phenytoin, so they can choose better treatments for future children.
StrasbourgAges 3 months–17 years - NCT06524479Recruiting
Sleep and wake brain activity in epilepsy
This study looks at how the brain works during sleep and waking hours in people with epilepsy that does not respond to medication. It uses a special brain recording method called SEEG to help understand seizures and plan potential surgery.
Beijing, Beijing MunicipalityAges 14–65
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Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 339 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.