Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 328 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06934356Recruiting
Awareness and brain arousal study
This study looks at how your brain becomes aware of things—like sounds and images—by measuring pupil size and brain activity. Healthy people may have an MRI; epilepsy patients with special brain electrodes already implanted can also join a part of the study.
New Haven, ConnecticutAges 13 years+ - NCT06579573RecruitingPhase 3
Testing a new drug for generalized tonic-clonic seizures in Japan
This study tests a new medicine (ONO-2017) for people with a type of epilepsy that causes whole-body seizures. It looks at whether adding this drug to your current seizure medicines can reduce how often those seizures happen.
AichiAges 12 years+ - NCT05981755Recruiting
Breathing rescue to prevent SUDEP in epilepsy
This trial tests a breathing rescue device to prevent SUDEP (sudden unexpected death in epilepsy) in people with hard-to-control focal epilepsy who are staying in the hospital for invasive brain monitoring.
Houston, TexasAges 18 years+ - NCT06924086Recruiting
Adaptive deep brain stimulation for children with epilepsy
This trial tests a new type of brain stimulation (adaptive deep brain stimulation) that adjusts in real time to stop seizures in children with Lennox-Gastaut syndrome. It's for children who haven't gotten enough help from medications and have frequent drop seizures.
LondonAges 5–14 - NCT06922175Recruiting
Study on cenobamate and healthcare use in epilepsy
This study looks at how cenobamate (a medication for seizures) affects healthcare use, like hospital visits or emergency room trips, in people with epilepsy whose seizures were not well-controlled by 2 to 5 other medicines. It is a real-world study, meaning it uses medical records to understand the impact.
Freiburg im Breisgau, GermanyAges 18 years+ - NCT06904079Recruiting
AI-based rehab study for serious mental disorders
This study uses computer analysis and AI to predict how people with severe mental disorders might recover and to suggest better support. It may help improve rehabilitation plans tailored to each person.
ShanghaiAges 18–65 - NCT06898749Recruiting
Dog therapy for adults with epilepsy
This study tests whether spending time with a therapy dog during psychomotor therapy can improve quality of life for adults with epilepsy that is not controlled by medication. Participants will have regular sessions with a dog as part of their therapy.
Saint-Étienne-de-Saint-GeoirsAges 18 years+ - NCT06524479Recruiting
Sleep and wake brain activity in epilepsy
This study looks at how the brain works during sleep and waking hours in people with epilepsy that does not respond to medication. It uses a special brain recording method called SEEG to help understand seizures and plan potential surgery.
Beijing, Beijing MunicipalityAges 14–65 - NCT05339438Recruiting
Brain scan mapping before epilepsy surgery
This study uses a special MRI scan to map parts of the front-temporal brain in people with drug-resistant epilepsy who may need surgery. The goal is to better plan surgery by showing which brain areas are involved.
NancyAges 18 years+ - NCT06865820Recruiting
Testing Project UPLIFT for people with epilepsy
This study tests whether a program called Project UPLIFT helps people with epilepsy feel better. It uses phone or online sessions to teach skills and support mental health.
Atlanta, GeorgiaAges 18 years+ - NCT06092125Recruiting
Brain disease imaging study with PET/MR scans
This trial uses advanced PET and MR scans to better understand and diagnose brain diseases like Alzheimer's, Parkinson's, epilepsy, and brain tumors. It may help identify new ways to track these conditions.
Beijing, Beijing MunicipalityAges 18–60 - NCT05065450Recruiting
Testing whether brain stimulation improves memory in epilepsy
This trial looks at ways to improve memory by targeting specific deep brain areas in people with epilepsy. You may be eligible if you are already scheduled for long-term video monitoring with implanted depth electrodes in the memory-related regions (amygdala, hippocampus, and nearby areas).
St Louis, MissouriAges 18–75 - NCT06241924Recruiting
Brain wave study in Parkinson's and epilepsy
This study looks at brain wave activity in areas that control movement, both in people with Parkinson's disease who already have deep brain stimulation electrodes and in people with epilepsy who are undergoing brain monitoring with stereo-EEG. The goal is to understand how brain signals change during normal movement and in movement problems, which may help improve treatments.
BordeauxAges 18–75 - NCT06432907Recruiting
Brain signal study during movement in epilepsy patients
This study records brain signals from electrodes already placed in your brain for medical reasons. It looks at how your brain controls movement, which could help develop future devices for people with paralysis.
MoscowAges 18–70 - NCT05393518Recruiting
Study linking brain signals to anxiety in people with epilepsy
This study looks at how brain electrical signals relate to anxiety symptoms in people with drug-resistant epilepsy. It compares people who do (or do not) meet criteria for generalized anxiety disorder, to better understand anxiety in this setting.
BordeauxAges 18–65 - NCT06736002Recruiting
Vitamin D for epilepsy: fewer seizures, less fatigue
This trial tests whether high doses of vitamin D can help reduce seizures and improve fatigue and quality of life in adults with refractory epilepsy who have not responded well to at least two medications.
TainanAges Any age - NCT06716801Recruiting
How cenobamate works as early add-on treatment for epilepsy
This study looks at how well cenobamate works when added to other seizure medications for adults with focal epilepsy. It uses real-world data from medical records to see how people respond to treatment.
Paris, FranceAges 18 years+ - NCT06720922Recruiting
Laser surgery for drug-resistant epilepsy
This trial tests a new, less invasive surgery called MRI-guided laser ablation (MRgLITT) for people with drug-resistant mesial temporal lobe epilepsy. It aims to stop or reduce seizures by using a laser to destroy the tiny area of the brain causing them.
Beijing, Beijing MunicipalityAges Any age - NCT06724029Recruiting
Neurosurgery outcomes research for multiple conditions
This study collects data from people having brain or spine surgery for many different conditions. It aims to understand how well different treatments work and how people recover. If you are scheduled for certain brain, spine, or nerve surgeries, you may be able to join.
Bergamo, BGAges 18 years+ - NCT06700356Recruiting
Can a brain stimulator detect seizures in the thalamus?
This study tests whether a special brain stimulator (already implanted in some people with epilepsy) can detect seizures in the thalamus. It may help improve seizure monitoring without extra surgery.
Rochester, MinnesotaAges 18 years+ - NCT06668519Recruiting
brain wave study in children with seizures and other conditions
This study uses a special brain scan (magnetoencephalography, or MEG) to look at brain activity in children with conditions like seizures, brain tumors, autism, and others. It may help doctors learn more about how these conditions affect the brain.
ShanghaiAges 1 month–18 years - NCT06625112Recruiting
STXBP1 disorder clinical trial readiness study
This study is for people with a confirmed STXBP1 genetic change to help prepare for future clinical trials. It collects information about the condition to better understand it.
AntwerpAges Any age - NCT06617845Recruiting
Optimizing brain stimulation for epilepsy
This study aims to find the best settings for brain stimulation devices already implanted in patients with epilepsy. It may help improve seizure control by adjusting how the device works.
Rochester, MinnesotaAges 6 years+ - NCT06585618Recruiting
Pediatric Deep Brain Stimulation Registry
This study creates a list of children who already have or plan to get Deep Brain Stimulation (DBS) to see how it helps with movement problems. Joining helps doctors learn more about how DBS works in kids.
Boston, MassachusettsAges birth–18 years
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Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 328 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.