Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 325 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05871372Recruiting
Study brain circuits behind mood using brain monitoring
This study looks at how brain networks relate to mood and depression by recording brain activity during specific procedures. You may be able to join if you’re already having brain monitoring for epilepsy or are part of a depression deep brain stimulation program.
Houston, TexasAges 21–70 - NCT05876910Enrolling by invitation
Study brain signals for stopping speech during epilepsy care
This study looks at how the brain helps stop ongoing speech. It may help researchers understand brain control during medication-resistant epilepsy surgery, using recordings from implanted electrodes.
San Francisco, CaliforniaAges 18–65 - NCT05819008Recruiting
Online brain testing for people with neurological conditions
This trial studies how well a remote, online memory and thinking assessment works for people with neurological disorders or injuries. You may be invited if you can do the computer-based testing and speak Swedish.
UmeåAges 18 years+ - NCT05688683Recruiting
Brain recording during awake surgery to study motor learning
This study uses special brain recordings during an awake surgical procedure to understand how the brain learns new movement and sensation skills. If you can comfortably take part in a simple task during surgery, you may help researchers learn how learning works in humans.
ParisAges 18 years+ - NCT05664854Recruiting
Vagus nerve stimulation guided by body imaging
This study uses a painless body scan method (electrical impedance imaging) and a targeted vagus nerve stimulation to see if it helps people with conditions that might respond to this kind of nerve treatment. If you may benefit from vagus nerve stimulation, this trial may help doctors learn whether the approach is effective and safe for you.
London, Greater LondonAges 18 years+ - NCT05594017RecruitingEarly Phase 1
Test medicine to change brain rhythms and study memory
This early research study tests whether a medicine can change the brain’s electrical “rhythms” while people do memory-related tasks. It may help researchers understand how brain timing affects memory in people who are already being evaluated with specialized brain electrode monitoring.
Dallas, TexasAges 18–55 - NCT05529264Recruiting
EEG study in adults with epilepsy and brain recordings
This study uses brain recordings to better understand epilepsy signals. It may help people who need EEG monitoring for clinical care, and it may also use healthy adults as comparison participants.
Lebanon, New HampshireAges 18 years+ - NCT05450237Enrolling by invitation
Testing thinking and memory questionnaires in people with brain injury
This study checks how well certain questionnaire and testing tools work for people who have brain damage from neurologic conditions and ongoing brain inflammation. It may help future patients by improving which tests are most accurate and easy to use.
Pozzilli, IserniaAges 18–80 - NCT05435859Enrolling by invitation
Mapping the brain area for speech during surgery
This study uses tiny brain electrodes placed during surgery to better understand how a brain region helps with speech. The results may guide safer brain mapping during surgery for people with epilepsy or brain tumors.
San Francisco, CaliforniaAges 18–70 - NCT05450978Recruiting
Study drug levels in epilepsy meds during pregnancy and breastfeeding
This study measures how much epilepsy medicine (lamotrigine, levetiracetam, or oxcarbazepine) your body absorbs during pregnancy and breastfeeding. It may help doctors better understand dosing and safety during these times.
Pittsburgh, PennsylvaniaAges 18–45 - NCT05380921Enrolling by invitation
Dry-electrode EEG headset for VA telehealth visits
This trial is testing a new “dry electrode” EEG headset used during EEG testing done as an outpatient (and possibly from home/clinic by telehealth). It may help make EEG recordings easier and more comfortable compared with traditional setups.
Miami, FloridaAges 18 years+ - NCT05406349Recruiting
Study of brain activity for space memory using epilepsy implants
This study looks at how your brain represents locations in space, including how it relates to you (beyond your “self”). It uses special epilepsy-related implants or procedures to record brain activity, which may help researchers understand spatial thinking.
Boston, MassachusettsAges 18–70 - NCT05313308Recruiting
Survey of midazolam use in non-convulsive seizure emergencies
This trial is a survey about how midazolam is used in people with non-convulsive status epilepticus, especially when it’s given outside a medical facility and when an extra dose is needed. It may help doctors better understand real-world treatment patterns and safety.
TokyoAges Any age - NCT05273970Enrolling by invitation
Brain recording study during electrode surgery for drug-resistant epilepsy
This study uses special brain recordings done during electrode implantation to better understand brain activity in people whose symptoms are hard to control with medications. The goal is to help doctors improve how they evaluate and treat certain brain or nerve conditions.
Phoenix, ArizonaAges 18–80 - NCT05289934Recruiting
Recorded music to see how it affects seizures
This study is testing whether listening to recorded music can change seizure activity and brain-wave patterns in children monitored in an epilepsy center. Your child might benefit by helping researchers learn how music could affect seizures during close observation.
Baltimore, MarylandAges 4–17 - NCT05285059Recruiting
Study how children with epilepsy learn
This trial studies how children with epilepsy learn and process information compared with children without brain, mental health, or learning conditions. It may help researchers understand the learning needs of children living with epilepsy.
Bron, BronAges 8–14 - NCT05222594Recruiting
Brain language study using electrodes during epilepsy care
This study looks at how the brain processes language using recordings from electrodes placed during epilepsy treatment. If you’re already being considered for this type of brain monitoring, the study’s tasks may help researchers better understand language function in the brain.
Boston, MassachusettsAges 18–85 - NCT05140265Recruiting
Uses EEG and medical records to build a privacy-protected database
This study creates a large, de-identified database by combining EEG test recordings with basic clinical information from medical records. It helps researchers use brain-wave data for future research while protecting your identity.
Albuquerque, New MexicoAges 18 years+ - NCT05085704Recruiting
Brain scans to study metabolism in healthy and diabetic people
This study uses MRI brain scans at different strengths to measure how the brain uses energy (metabolism) in health and in people with genetically confirmed G1D. It may help researchers understand brain energy changes related to metabolic disease and diabetes.
New York, New YorkAges 16–80 - NCT05101161Recruiting
Neurofeedback delivered through implanted brain stimulation
This study tests a brain “feedback” approach using electrodes already placed as part of standard medical care. It aims to see whether this method is safe and helpful for people undergoing deep brain stimulation after surgery.
Zurich, Canton of ZurichAges 18 years+ - NCT05126914Recruiting
Follow-up study for rare epilepsy in children
This study follows children and teens with rare forms of epilepsy to better understand their condition over time in real-life care. It may help doctors improve future care plans and support for families.
AngersAges Up to 15 years - NCT05014841Enrolling by invitation
Brain electrode study of speech across different languages
This study uses electrodes placed on the brain during surgery to understand how speech is represented in different languages. It may help doctors better map language areas and improve surgical planning for people having brain surgery.
San Francisco, CaliforniaAges 18–70 - NCT04861051RecruitingPhase 1
Study ketamine effects on brain sensations in adults
This Phase 1 study tests how ketamine changes “dissociative” experiences—feelings of being disconnected from thoughts or surroundings—in adults. You may be helping researchers better understand ketamine’s effects, which could guide safer future uses.
Palo Alto, CaliforniaAges 18 years+ - NCT04715646RecruitingPhase 3
Brivaracetam study for children with hard-to-control seizures
This trial looks at how safe brivaracetam is and how well it can be used in children and teens with certain types of epilepsy that are not well controlled. It may help families who are dealing with frequent focal seizures despite taking seizure medicines.
Hawthorne, New YorkAges 1 month+
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Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 325 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.