Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 339 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06922175Recruiting
Study on cenobamate and healthcare use in epilepsy
This study looks at how cenobamate (a medication for seizures) affects healthcare use, like hospital visits or emergency room trips, in people with epilepsy whose seizures were not well-controlled by 2 to 5 other medicines. It is a real-world study, meaning it uses medical records to understand the impact.
Freiburg im Breisgau, GermanyAges 18 years+ - NCT06924086Recruiting
Adaptive deep brain stimulation for children with epilepsy
This trial tests a new type of brain stimulation (adaptive deep brain stimulation) that adjusts in real time to stop seizures in children with Lennox-Gastaut syndrome. It's for children who haven't gotten enough help from medications and have frequent drop seizures.
LondonAges 5–14 - NCT06934356Recruiting
Awareness and brain arousal study
This study looks at how your brain becomes aware of things—like sounds and images—by measuring pupil size and brain activity. Healthy people may have an MRI; epilepsy patients with special brain electrodes already implanted can also join a part of the study.
New Haven, ConnecticutAges 13 years+ - NCT06958341Recruiting
Brain and nerve disease registry with optional fluid collection
This study collects extra fluid from a spinal tap to learn more about brain and nerve diseases. It may help find better treatments in the future.
Berlin, State of BerlinAges Any age - NCT06975800Recruiting
How social feedback affects brain waves
This study looks at how getting feedback from others affects brain activity. Researchers will measure your brain waves while you do simple tasks, which may help us understand how social signals work in the brain.
Lebanon, New HampshireAges 18–65 - NCT06976788Recruiting
Healthy volunteers needed for brain imaging study on epilepsy
This trial is creating a database of brain scans from healthy people to improve understanding of epilepsy. You would have one PET scan of your brain to help researchers develop new imaging methods.
MarseilleAges 18–65 - NCT06978842Recruiting
Seizure prediction study with a wearable EEG headband
This study tests a wearable device that records brain activity to predict seizures. It might help you manage your epilepsy if you have seizures at least once a day but no more than two in the last three months.
HaifaAges 12 years+ - NCT07041619Recruiting
New stimulation implant trial for epilepsy
This trial tests a new type of stimulation placed under the skin to help control seizures in people with epilepsy. It is for patients whose seizures are not controlled with medication and who cannot have surgery.
BudapestAges 18–65 - NCT07046676RecruitingPhase 4
Using genetics to personalize valproate treatment for epilepsy
This trial studies how a person's genes affect their response to the epilepsy drug valproate. The goal is to find the best dose for each patient to improve seizure control and reduce side effects.
Hengyang, HunanAges Any age - NCT07085598Recruiting
Vitamin D3 for heart nerve health in men with epilepsy
This study tests whether taking vitamin D3 supplements can improve how well the nerves controlling your heart work in men with epilepsy who have low vitamin D levels. If you have low vitamin D from taking certain epilepsy medicines, this trial may help understand if vitamin D can support your heart health.
Dhaka, ShahbagAges 20–40 - NCT07088835Recruiting
Safety study of ear-worn seizure monitor
This study tests a new ear-worn sensor to monitor brain activity. It will see if the device is safe and easy to use for recording seizures. Healthy volunteers and people with suspected seizures are both needed.
New York, New YorkAges 18–70 - NCT07096414Recruiting
Vitamin D3 and brain waves in men with epilepsy and low vitamin D
This trial tests whether taking vitamin D3 supplements changes brain wave activity in men with epilepsy who also have low vitamin D levels. It aims to see if vitamin D could help improve brain function.
Dhaka, Shahbag, DhakaAges 20–40 - NCT07116330Recruiting
Seizures starting after 50: testing heart and blood vessel risk
This study looks at whether checking and treating heart and blood vessel risk factors can help people who start having seizures after age 50. It includes two parts: one that adds a risk check to your regular care, and one that uses your medical records to learn more about this condition.
BoråsAges 50 years+ - NCT07190976Recruiting
EEG monitoring for stroke patients
This study uses EEG (a harmless brain wave test) to monitor stroke patients in the hospital. It aims to learn more about brain activity after a stroke, which could help improve care.
Chaïdári, AthensAges 18 years+ - NCT07234695RecruitingPhase 3
Levetiracetam to prevent seizures in adults with Down syndrome and Alzheimer's
This trial tests if levetiracetam, a seizure medication, can prevent seizures in adults with Down syndrome who also have Alzheimer's disease. It aims to help manage a common complication and improve quality of life.
Granada, AndalusiaAges 40 years+ - NCT07329257Recruiting
Project PENGUIN: Study of rare brain development disorders
This study looks at rare and ultra-rare conditions that affect brain development. It aims to learn more about what causes these conditions. You may join if you or your child have a diagnosed or suspected neurogenetic disorder.
Columbia, MissouriAges Up to 99 years - NCT07377032RecruitingPhase 3
L-serine for GRIN-related neurodevelopmental disorders
This trial tests whether an amino acid supplement called L-serine can help people with GRIN-related neurodevelopmental disorders. These disorders are caused by specific genetic changes that affect brain function, and the study aims to see if L-serine can improve symptoms.
LyonAges 2–30 - NCT00575081Recruiting
Brain mapping during stereotactic procedures
This study builds a “brain atlas” by collecting information during stereotactic brain procedures. It may help doctors better plan and understand these brain procedures in the future.
Nashville, TennesseeAges 6–90 - NCT01662453Recruiting
Study risk factors for sudden unexplained death in epilepsy
This study looks at what factors may be linked to sudden, unexplained death in people with epilepsy. Your family’s willingness to participate matters, because the researchers compare cases of sudden unexplained death to people with epilepsy who have not had it.
New York, New YorkAges Any age - NCT02216500Recruiting
Study ketogenic diet effects in people with epilepsy
This study looks at how a high-fat, low-carbohydrate ketogenic diet may change electrical activity in the brain and related body measurements in people with epilepsy. You may be asked to follow the diet and keep records so the researchers can compare changes over time.
Gainesville, FloridaAges Up to 50 years - NCT02670161Enrolling by invitationPhase 4
Using electronic records to improve care for brain and nerve conditions
This study looks at how doctors use electronic medical records to improve treatment and care for people with certain brain and nervous system conditions. It may help because it tests practice-based approaches across neurology visits.
Evanston, IllinoisAges 18–100 - NCT07399327Recruiting
SEEG thermocoagulation for hard-to-treat epilepsy
This study is looking at how well a procedure called SEEG thermocoagulation (a way to stop seizures by heating a small area of brain tissue) works for people with epilepsy that doesn't improve with medication. By joining, you will help doctors understand why this treatment works for some people and not others.
MarseilleAges 12 years+ - NCT07403266RecruitingPhase 3
Full-spectrum cannabis oil for seizures in tuberous sclerosis
This trial tests a full-spectrum cannabis extract to see if it reduces seizures in people with tuberous sclerosis complex (TSC) whose seizures have not been controlled by other treatments. If it works, it could offer a new option for managing hard-to-treat epilepsy.
MadridAges 2–65 - NCT07417280Recruiting
Focused ultrasound for neurological disorders
This trial tests a gentle ultrasound treatment (LIFUS) for people with various brain conditions like epilepsy, tumours, or movement disorders. It aims to see if this non-invasive approach can help where other treatments are being used.
Toronto, OntarioAges 18–85
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Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 339 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.