Clinical trials
Function clinical trials
Below are recruiting function clinical trials, each written for real people, not researchers. We’re tracking 2,474 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05908591Recruiting
Pregnancy sleep study on breathing, blood vessel function, and safety
This study looks at how sleep and breathing changes during pregnancy may affect blood vessel function and pregnancy safety. You may be asked about your sleep and possibly have health checks during the middle of pregnancy.
Edmonton, AlbertaAges 18 years+ - NCT05909267Recruiting
Testing dopamine-targeted treatment for depression and body inflammation
This study looks at how changing dopamine signaling may affect motivation and movement in people with major depression, and it also involves healthy volunteers. It may help researchers understand whether dopamine changes can improve symptoms and how inflammation may relate to brain function.
SteglitzAges 18–65 - NCT05903859RecruitingPhase 3
Study to improve fertility in men after spinal cord injury
This phase 3 study tests a treatment to improve reproductive function (fertility-related measures) in men who have had a traumatic spinal cord injury. If you may be eligible, it could help researchers see whether the treatment improves reproductive outcomes for men with spinal cord injury.
Miami, FloridaAges 18 years+ - NCT05861999RecruitingPhase 4
Risdiplam for young children with SMA after gene therapy plateau
This trial studies whether risdiplam is safe and helpful for children under 2 with spinal muscular atrophy (SMA) whose function has leveled off or declined after gene therapy. It may be an option if you saw benefits from gene therapy but then noticed a stop or setback in key abilities.
Little Rock, ArkansasAges 3 months–2 years - NCT05869812RecruitingPhase 2
HMB supplement study to help recovery after surgery
This trial tests whether taking an HMB supplement after surgery can help improve muscle size and function during recovery. It may be helpful if you are a female athlete planning rehab at a specific physical therapy clinic.
Overland Park, KansasAges 18–45 - NCT05849532Recruiting
Home electrical exercise for walking after stroke
This trial tests a home-based program using electrical stimulation to help people with long-term stroke improve walking and leg movement. If you qualify, you may use the device and a smartphone app at home with guidance from the study team.
Chicago, IllinoisAges 18–90 - NCT05877846Recruiting
Personalized care to improve physical function in older adults
This study looks at precision (personalized) approaches to help older adults improve physical function. It may include giving a specific supplement depending on lab results, and it requires regular study visits and ability to complete procedures.
Chapel Hill, North CarolinaAges 65–85 - NCT05857969RecruitingPhase 1
Testing cancer drug response on removed tumor tissue
This early study uses tumor tissue (or bone marrow from blood cancers) and performs lab tests to see which cancer drugs may work better for each person. It also collects genetic information from blood or a saliva swab to help understand why cancers respond differently.
Miami, FloridaAges 1 day–21 years - NCT05876169Enrolling by invitation
Study how jaw surgery changes neck and jaw movement
This study looks at how orthognathic (jaw alignment) surgery affects how your jaw and neck muscles move. It may help doctors better understand recovery and movement changes after surgery.
UmeåAges 16–50 - NCT05856136RecruitingPhase 4
Study how opioid exposure affects diaphragm muscle function
This study looks at whether receiving opioids for pain during lower-leg surgery changes how well the diaphragm muscle (the main breathing muscle) works afterward. It compares breathing muscle function in people who do and do not have certain lung conditions.
Rochester, MinnesotaAges 18 years+ - NCT05856552Recruiting
Study on how depression affects older women’s health
This study looks at how depression impacts the health and social life of older women. It aims to understand the effects of depression so care and support can improve.
Chennai, Tamil NaduAges 55 years+ - NCT05525507RecruitingPhase 1
Test early immune-tolerance treatment for matched kidney transplant patients
This Phase 1 study tests a treatment plan given after a kidney transplant to help the immune system stay calm and reduce the risk of rejection. Participants must have a well-functioning kidney transplant from a closely matched living donor and meet health and safety requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT04232085RecruitingPhase 2
Stem cell transplant to rebuild immunity in genetic immune disorders
This Phase 2 trial tests a stem cell (bone marrow) transplant approach to restore bone marrow function and immune function in people with certain inherited immune problems. If you have one of these conditions and a suitable donor, the study may offer a path to rebuild blood and immune systems.
Baltimore, MarylandAges 4 months–50 years - NCT05830942Recruiting
Training walks plus brain stimulation for thinking skills in older adults
This study tests whether a structured walking exercise, combined with brain stimulation and brain scans, can improve or slow decline in thinking skills. It’s aimed at older adults who notice memory or confusion getting worse.
Gainesville, FloridaAges 65 years+ - NCT05823727Recruiting
Collagen supplement study before and after knee replacement
This study tests whether taking collagen peptides can improve how knee tissues heal and remodel after total knee arthroplasty (knee replacement). It also looks at functional recovery and wound healing, especially during the physical therapy period in Little Rock.
Little Rock, ArkansasAges 50–75 - NCT05831085Recruiting
Compare procedures to improve heart blood flow in diabetes
This study compares two ways to restore blood flow to the heart—stent placement (PCI) versus bypass surgery (CABG)—in people with diabetes and significant multi-vessel coronary artery disease. It looks at outcomes using both standard heart tests and additional imaging/functional measurements to guide the best revascularization strategy.
Palo Alto, CaliforniaAges 20 years+ - NCT05825898Enrolling by invitation
Treatment outcomes for severe leaking tricuspid valve
This study looks at what happens to adults with moderate-to-severe or severe tricuspid valve “leaking” after different treatment types, such as catheter-based or surgery. It may help doctors understand which approach works best for people with severe valve leakage and symptoms.
Rochester, MinnesotaAges 18 years+ - NCT05846802Recruiting
Gastroparesis and stomach symptoms registry for adults
This registry is for adults with long-lasting stomach emptying problems or related symptoms, helping researchers better understand patterns of nausea, pain, and fullness. You may be able to join if you meet specific symptom and test results, and can complete a stomach-emptying scan.
Scottsdale, ArizonaAges 18–85 - NCT05812339Enrolling by invitation
Mapping tests for stomach symptoms using body-surface sensors
This study checks whether a noninvasive “mapping” test placed on the belly and chest can help tell apart people with certain upper stomach symptoms from healthy controls. It may help researchers better understand stomach function and symptoms without relying only on invasive tests.
Calgary, AlbertaAges 18 years+ - NCT05843604Recruiting
Brain and thinking tests to study OCD treatment resistance
This study looks at brain and thinking (cognitive) markers to understand why some people with obsessive-compulsive disorder (OCD) don’t respond as well to treatment. If you have OCD, you may be asked to take tests and follow the study rules to help researchers better predict treatment resistance.
PoitiersAges 18–70 - NCT05814497Recruiting
Brain scan study of how kids process chronic pain
This study looks at how the brain processes pain sensations in children with certain long-lasting pain conditions. It may help researchers understand what’s happening in the nervous system and guide better treatments.
Cincinnati, OhioAges 10–17 - NCT05826587Recruiting
Mobile coaching to prevent falls during heart rehab
This study adds a personalized home exercise program delivered by a smartphone app to standard outpatient heart rehabilitation. It aims to improve balance and strength to lower the chance of falling during the rehab period.
Scottsdale, ArizonaAges 18 years+ - NCT05832268Enrolling by invitation
Pelvic floor recovery after childbirth anal sphincter injury
This study looks at how the pelvic floor (the support muscles and tissues) works in people who had a specific anal sphincter injury during vaginal birth, compared with people who had uncomplicated vaginal deliveries. It may help doctors better understand recovery and function after childbirth injuries.
OsloAges 18 years+ - NCT05312255Recruiting
Non-drug help to improve quality of life in myeloma
This study tests non-chemotherapy supports meant to improve quality of life and immune health for people with multiple myeloma (or related conditions). Depending on the group, it may involve activities, nutrition, and/or a medication like a beta blocker.
Buffalo, New YorkAges 18 years+
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Common questions
- Are there clinical trials for function?
- Yes. Clin2 currently lists 2,474 recruiting function studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a function trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a function trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.