Clinical trials
Functionality clinical trials
Below are recruiting functionality clinical trials, each written for real people, not researchers. We’re tracking 2,474 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06286085Recruiting
Comparing asthma tests in Portsmouth
This study looks at different ways to test for asthma. It uses data from patients who have already been evaluated at the Portsmouth asthma service, to see which tests work best for diagnosing asthma.
PortsmouthAges 18 years+ - NCT06286891Recruiting
Frailty and lung function after pulmonary endarterectomy
This study looks at how frailty, physical ability, and lung function change in people who have had surgery to remove blood clots from the lungs (pulmonary endarterectomy). It aims to help doctors better understand recovery after this procedure.
São Paulo, São PauloAges 18 years+ - NCT06291389Recruiting
Airway pressure changes during tummy tuck surgery
This trial tests how changes in airway pressure during tummy tuck surgery affect breathing after the operation. It is for healthy adults having a tummy tuck with muscle tightening.
Tanta, EgyptAges 20–50 - NCT06291077RecruitingPhase 4
Belatacept vs anticalcineurins after kidney transplant
This study is comparing two medications after kidney transplant: Belatacept and anticalcineurins (like tacrolimus). It looks at how each affects blood vessel health. If you are more than a year post-transplant and have stable kidney function, you may be eligible.
RouenAges 18–75 - NCT06291675Recruiting
Hormone therapy's effect on heart and organ fat
This study uses MRI scans to see how gender-affirming hormone therapy affects heart muscle, heart function, and fat in the heart, liver, and pancreas. It may help us understand long-term health effects of hormone therapy.
Vienna, State of ViennaAges 18 years+ - NCT06288763Recruiting
Nerve transfer to improve arm function in high-level tetraplegia
This study tests whether transferring a nerve from a working muscle can help restore function in the arm or hand for people with high-level tetraplegia. It may be an option if you've stopped improving with standard therapy.
Stanford, CaliforniaAges 18–80 - NCT06293638Recruiting
Brain changes during deep brain stimulation for essential tremor
This study looks at how deep brain stimulation (DBS) affects brain networks in people with essential tremor (ET). The goal is to understand the brain changes that happen during DBS treatment, which may help improve the therapy.
Cleveland, OhioAges 30–80 - NCT06034509Recruiting
Thinking and blood vessel health after head injury
This study looks at how a past traumatic brain injury (TBI) might affect your thinking skills and blood vessel health over time. You may be eligible if you had a TBI at least 3 years ago and have already completed an earlier evaluation at the National Intrepid Center of Excellence (NICoE).
Bethesda, MarylandAges 18–74 - NCT03857529Recruiting
Rehab training for stroke arm control using brain and hand stimulation
This study tests whether non-invasive brain stimulation plus a hand/arm electrical stimulation device can improve how well your stroke-affected arm and hand move during therapy tasks. You would take part in screening and then receive these combined rehab approaches to see if motor control improves.
Cleveland, OhioAges 21 years+ - NCT05895344Recruiting
Compare proton vs modern radiation effects on thinking
This study compares two types of radiation—proton therapy versus modern fractionated radiation—to see how they affect long-term thinking (cognitive function) and daily abilities in people with a specific skull-base tumor. It may help clarify which radiation approach best protects brain and nerve function over time.
CaenAges 18–70 - NCT05805202Recruiting
Study rare gene changes in atypical HUS for tailored care
This study looks at how rare gene mutations may explain atypical HUS (aHUS) and how that could guide more personalized treatment. It mainly involves people who have had aHUS affecting blood counts and kidneys.
Ranica, BGAges Any age - NCT05866003Recruiting
Brain stimulation plus hand training after stroke
This trial tests whether a combination of brain stimulation and structured hand practice can improve hand movement for people recovering from stroke. It may help because the training targets upper-limb function while using therapy intended to support recovery.
Cleveland, OhioAges 21–90 - NCT05943652Recruiting
Study of how functional overlay affects movement disorders
This study looks at movement disorders that are functional (not caused by damage to the nervous system) or non-functional, and how a “functional overlay” may change symptoms. It is observational, meaning it does not test a new treatment, but it may help researchers better understand these differences and improve care.
Graz, StyriaAges 18–18 - NCT06258161Recruiting
How spinal surgery affects balance and reach
This study looks at how adult spinal deformity surgery affects your ability to reach forward and balance. It compares the results of surgery with healthy adults to see if the surgery helps improve everyday movements.
Kansas City, KansasAges 18 years+ - NCT06258538Recruiting
Robot-assisted arm therapy and exercise after stroke
This study tests if combining arm exercises with two types of robot-assisted therapy helps people who have had a stroke improve their arm movement, daily activities, and quality of life. It is designed for individuals with moderate arm weakness.
Taoyuan, TaoyuanAges 20–75 - NCT06261463Recruiting
Peer-led support group for refugee families in Chicago
This study is testing a support program led by trained peers to help refugee families strengthen family bonds and cope with challenges. It is designed for Arabic-speaking families who have recently settled in Chicago.
Chicago, IllinoisAges 12–55 - NCT06261502RecruitingPhase 2
CBD for Anxiety in Fragile X Syndrome
This trial tests if cannabidiol (CBD) can help with anxiety and improve brain function in people with Fragile X syndrome. Participants will receive CBD or a placebo, and may have brain scans (MRI) or magnetic stimulation (TMS) to see how it works.
Sherbrooke, QuebecAges 7–40 - NCT06261060RecruitingPhase 2
Sirolimus to improve blood cell production in RUNX1 familial platelet disorder
This trial tests a low dose of sirolimus, a medicine that may help your bone marrow make more blood cells, especially platelets. It is for people with a specific genetic change (RUNX1) that affects blood cell production.
Houston, TexasAges 18 years+ - NCT06273046Recruiting
Biofeedback for bowel control problems
This trial tests a non-invasive biofeedback technique to help people regain control of bowel movements. It may be an option for those with frequent stool leakage or difficult constipation, but participants must not have certain other digestive or neurological conditions.
BarcelonaAges 18–75 - NCT06270589Recruiting
Intense Exercise with Mindfulness for Kids' Thinking Skills
This study tests whether combining high-intensity interval training (short, intense exercise bursts) with mindfulness recovery (focusing on the present moment) can improve thinking skills like focus and planning in children. It may help 10-to-12-year-olds who are generally healthy.
West Lafayette, IndianaAges 10–12 - NCT06246357RecruitingPhase 2
Testing adrenal gland function with a special scan
This trial uses a special PET scan (68Ga-PentixaFor) to check how well your adrenal glands are working if you have high aldosterone or cortisol levels. It helps doctors see if the glands are making too much hormone, which may guide treatment.
Bethesda, MarylandAges 18–120 - NCT06236919Recruiting
Virtual reality for emotional regulation in kids and teens
This study tests a virtual reality program designed to help children and teens learn to manage their emotions. It's offered in schools and aims to improve emotional regulation skills.
BarcelonaAges 10–16 - NCT06245681Recruiting
How Hormone Therapy Affects the Heart and Liver
This study looks at how cross-sex hormone treatment affects the heart and fat in the liver. It aims to help understand the safety of hormone therapy in transgender individuals.
Vienna, State of ViennaAges 18–99 - NCT06244472Recruiting
New brain scanner for fast brain imaging
This study uses a new type of brain scanner (MEG) to take very fast pictures of brain activity. It's for healthy people or those who've had a mild concussion recently.
BronAges 18–70
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Common questions
- Are there clinical trials for functionality?
- Yes. Clin2 currently lists 2,474 recruiting functionality studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a functionality trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a functionality trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.