Clinical trials
Gastric Cancer Stage clinical trials
Below are recruiting gastric cancer stage clinical trials, each written for real people, not researchers. We’re tracking 244 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05427383RecruitingPhase 2/Phase 3
KN026 plus chemo for HER2-positive stomach cancer after first treatment failure
This trial tests KN026 together with chemotherapy in people with HER2-positive advanced stomach (or gastro-esophageal junction) cancer that has already grown despite first-line treatment with trastuzumab plus chemotherapy. It may help by targeting HER2 while also using chemotherapy to control the cancer.
BeijingAges 18 years+ - NCT06371586RecruitingPhase 2
Neo-Sequence 2: New drug combo for advanced stomach cancer
This trial tests a new treatment plan for advanced stomach cancer using chemotherapy, anti-angiogenesis therapy (to cut off tumor blood supply), and immunotherapy (to help your immune system fight cancer). The goal is to see if this combination works better before surgery.
BeijingAges 18–75 - NCT06427941RecruitingPhase 1
Study of BGB-B2033 drug for advanced solid tumors
This trial tests a new drug, BGB-B2033, alone or with other treatments, for people with advanced liver, stomach, lung, or germ cell cancers that have not responded to standard therapy. The goal is to see if the drug is safe and works against these tumors.
Goodyear, ArizonaAges 18 years+ - NCT05715931RecruitingPhase 2
Surgery chemotherapy plus anti-HER2 and anti–immune therapy for HER2 stomach cancer
This Phase 2 trial tests adding chemotherapy plus trastuzumab and toripalimab around the time of surgery for HER2-positive, locally advanced stomach or esophagus-stomach junction cancer. It aims to shrink the cancer and reduce the chance it comes back by attacking it through more than one pathway.
Hangzhou, ZhejiangAges 18–80 - NCT07757165RecruitingPhase 2
Surgery after drug treatment for advanced stomach cancer
This trial is for people with advanced stomach cancer that has shrunk after initial chemotherapy or targeted therapy. It compares whether adding surgery to continued medical treatment is better than staying on medical treatment alone, with the goal of improving outcomes.
ShanghaiAges 18–75 - NCT04284943Recruiting
Surgery for stomach cancer and diabetes
This trial tests a surgery for early-stage stomach cancer that also aims to improve type 2 diabetes by changing how your body processes food. It might be an option if you have both conditions and are not using insulin.
SeoulAges 20–69 - NCT04295473Recruiting
Test of smaller-incision stomach surgery for gastric cancer
This trial studies a stomach cancer surgery done with fewer/smaller incisions (laparoscopic with reduced ports). It may help people with certain early-to-mid stage stomach cancers by comparing whether this approach is safe and effective for them.
Nanchong, SichuanAges 18–90 - NCT07353684RecruitingPhase 2
Adebrelimab plus apatinib with chemo for gastric cancer
This trial tests a combination of two targeted drugs (adebrelimab and apatinib) with standard chemotherapy (SOX regimen) before surgery for gastric cancer that cannot be removed right away. The goal is to shrink the tumor enough to make surgery possible.
Beijing, Beijing MunicipalityAges 18–75 - NCT06679244Recruiting
New surgery for upper stomach cancer
This trial tests a new surgical technique for patients with cancer in the upper part of the stomach or where the stomach meets the esophagus. It aims to see if the new approach is safe and effective for removing the tumor and nearby lymph nodes.
ShanghaiAges 18–80 - NCT06510010RecruitingPhase 2
Chemo plus H. pylori treatment for advanced stomach cancer
This trial tests whether adding H. pylori bacteria treatment to standard chemotherapy (before and after surgery) can improve outcomes for people with locally advanced stomach cancer. It combines oxaliplatin and S-1 chemo with antibiotics to clear the infection.
GuangzhouAges 18–75 - NCT04114136RecruitingPhase 2
Study tests pembrolizumab or nivolumab plus a diabetes-like drug
This Phase 2 study tests whether adding a metabolic (diabetes-related) medicine to an immune therapy (pembrolizumab or nivolumab) can better control certain solid tumors. It may help people whose standard treatment would usually be pembrolizumab or nivolumab alone.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04710758Recruiting
Keyhole surgery for advanced stomach cancer
This trial looks at laparoscopic (keyhole) total stomach removal for people with advanced stomach cancer in the upper or middle part of the stomach. It aims to see whether this operation approach is safe and useful based on your tumor stage and overall health.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04798820Recruiting
Diet coaching after stomach surgery for early stomach cancer
This trial studies whether intensive dietary education (diet coaching) after gastrectomy can improve patients’ nutrition and recovery. It is for people with early-stage primary stomach cancer who have no spread to distant organs.
SeoulAges 20–75 - NCT05180864Recruiting
Omentum saving surgery versus full removal in stomach cancer
This study compares two ways of doing surgery for gastric (stomach) cancer: saving the omentum versus removing it completely. It may help doctors learn which approach is safer and works better for cancer control and recovery.
MainzAges 18 years+ - NCT05450835Recruiting
Surgery technique comparison for stomach cancer near the esophagus
This study compares two ways surgeons reconnect the digestive tract after removing the whole stomach for certain stomach cancers near the esophagus. It aims to see which technique is safer and leads to better recovery and outcomes.
Quanzhou, FujianAges 18–75 - NCT05739045RecruitingPhase 2
Nivolumab plus SOX before and around stomach cancer surgery
This Phase 2 trial tests whether adding nivolumab to standard chemotherapy (SOX) given before and around surgery can improve outcomes for people with certain stomach or stomach–esophagus junction cancers. It aims to shrink or control the cancer and make surgery more effective.
Hangzhou, ZhejiangAges 18–80 - NCT05871099RecruitingPhase 3
Laparoscopic stomach surgery with added heated fluid chemotherapy
This trial compares standard laparoscopic surgery for stomach cancer versus the same surgery plus HIPEC, which is heated chemotherapy placed in the abdomen during the operation. It aims to see if adding the heated chemotherapy improves outcomes for people with higher-stage stomach cancer.
Qingdao, ShandongAges 18–80 - NCT05892289Recruiting
Robotic stomach surgery study for early cancer near the top
This study checks whether a specific robotic operation (proximal gastrectomy using a double-flap technique) is safe and feasible for early stomach cancer located near the top of the stomach. It may help patients by testing a surgical approach designed to remove the cancer while managing reconstruction and recovery.
Guangzhou, GuangdongAges 20–80 - NCT06157996RecruitingPhase 2
Lenvatinib, Tislelizumab, and CapeOX for advanced stomach cancer
This trial tests a combination of three drugs (lenvatinib, tislelizumab, and CapeOX chemotherapy) as the first treatment for advanced stomach or gastroesophageal junction cancer that is PD-L1 positive and has a low TMEscore. The goal is to see if this combination helps control the cancer better than standard treatments.
Guangzhou, GuangdongAges 18 years+ - NCT06461910RecruitingPhase 2
Immunotherapy, thymalfasin, and chemo before surgery for stomach cancer
This trial is testing a combination of three medicines—an immunotherapy (anti-PD-1), an immune booster (thymalfasin), and a chemotherapy regimen (SOX)—given before surgery to shrink stage III stomach or gastroesophageal junction cancer and improve outcomes.
Nanjing, JiangsuAges 18–75 - NCT06475170Recruiting
Double-tract reconstruction after stomach cancer surgery
This trial tests a new surgical method called 'λ+α' double-tract reconstruction after laparoscopic removal of the upper part of the stomach for early-stage stomach cancer. It aims to see if this procedure improves recovery and quality of life for patients.
YangzhouAges 18–75 - NCT06504732RecruitingPhase 2/Phase 3
IAH0968 plus CAPEOX for HER2-positive gastric cancer
This trial tests a new drug (IAH0968) combined with chemotherapy (CAPEOX) for people with HER2-positive stomach or gastroesophageal junction cancer that has not been treated before or has spread.
Harbin, HeilongjiangAges 18–75 - NCT06521541Recruiting
Prehabilitation program for stomach cancer surgery patients
This study tests a program of nutrition, exercise, and emotional support before and during chemotherapy and stomach cancer surgery. It aims to help patients recover faster and have fewer complications.
Qingdao, ShandongAges 18 years+ - NCT06576921RecruitingPhase 2
Study of serplulimab with chemo before surgery for stomach cancer
This trial tests if adding serplulimab to standard chemotherapy before surgery can help shrink locally advanced stomach or gastroesophageal junction cancer. It aims to improve treatment outcomes for patients who are candidates for surgery.
Shijiazhuang, Heibei ProvinceAges 18–75
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Common questions
- Are there clinical trials for gastric cancer stage?
- Yes. Clin2 currently lists 244 recruiting gastric cancer stage studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastric cancer stage trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastric cancer stage trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Clinical Stage III Gastric Cancer AJCC v8
- Clinical Stage IV Gastric Cancer AJCC v8
- Gastric Cancer, Gastroesophageal Junction Cancer
- Clinical Stage IVB Gastric Cancer AJCC v8
- Gastric Cancer Stage III
- Gastric Cancer Stage IV
- Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.