Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,548 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05101746Enrolling by invitationPhase 2/Phase 3
Nitric oxide to protect brain and kidneys in babies during heart surgery
This trial studies whether giving nitric oxide during heart-lung bypass surgery can help protect a baby’s brain and kidneys. If you qualify, the study team will check outcomes after surgery to see if benefits happen compared with usual care.
Nashville, TennesseeAges birth–1 year - NCT05101161Recruiting
Neurofeedback delivered through implanted brain stimulation
This study tests a brain “feedback” approach using electrodes already placed as part of standard medical care. It aims to see whether this method is safe and helpful for people undergoing deep brain stimulation after surgery.
Zurich, Canton of ZurichAges 18 years+ - NCT05096715RecruitingPhase 1
Testing atezolizumab plus bevacizumab with SBRT for advanced liver cancer
This Phase 1 trial tests how well a combination treatment works for liver cancer that cannot be removed with surgery or other local treatments. It combines two immune/targeted medicines with a focused type of radiation (SBRT) to control the tumors.
Boston, MassachusettsAges 18 years+ - NCT02975310Recruiting
In-clinic endoscopy surgery for chronic sinus polyps
This trial tests an in-clinic (not hospital) endoscopic procedure to remove nasal polyps in people with chronic sinus inflammation, after usual medicines haven’t helped. It may help reduce nasal blockage and improve sinus symptoms, while comparing safety and outcomes after the procedure.
Vancouver, British ColumbiaAges 18 years+ - NCT04991103RecruitingPhase 2
Testing delaying stem cell transplant after early myeloma response
This Phase 2 study tests whether people with newly diagnosed multiple myeloma can safely delay or avoid an immediate stem cell transplant if they respond well to early treatment. It aims to see if this “response-adapted” approach can still control the disease while reducing the need for upfront transplant for some patients.
Birmingham, AlabamaAges 18 years+ - NCT04660487Recruiting
How diet carbs affect GVHD after bone marrow transplant
This study looks at whether certain types of gut carbohydrates (called FODMAPs) are linked to graft-versus-host disease (GVHD) after a bone marrow transplant. It may help doctors understand how diet could influence symptoms and outcomes for people with specific blood cancers.
Suzhou, JiangsuAges 18–60 - NCT05050799Recruiting
Testing a new device to place central lines in harder cases
This study tracks how well a new device (the Surfacer System) works when standard methods can’t place a central venous line (a larger tube into a major vein). It may help people who need a long-term access line but have blocked veins where usual procedures don’t work.
Tucson, ArizonaAges 18 years+ - NCT05041309Enrolling by invitation
Long-term follow-up after gene-modified cell treatment
This study is for people who have already received a special kind of cell therapy that involved modifying their genes. The purpose is to keep track of their health over a longer period of time to see how they are doing after the treatment.
Gilbert, ArizonaAges Any age - NCT05046444Recruiting
Testing tricky blood cancer diagnoses with advanced DNA sequencing
This study uses advanced DNA sequencing to figure out unclear or unusual blood (hematologic) conditions when standard tests are not enough. It may help your care team reach a more accurate diagnosis by better understanding what’s driving your illness.
MunichAges 18–99 - NCT05055297Recruiting
Drug-coated balloon for severe leg artery blockage in lower legs
This trial studies a “drug-coated balloon” procedure to improve blood flow in people with severe, long-lasting poor circulation in the lower leg arteries. It may help reduce repeat blockage after treatment for selected artery lesions below the knee.
Chandler, ArizonaAges 18 years+ - NCT05037968Recruiting
Test bone graft materials for multi-level back fusion surgery
This trial compares two bone-graft materials to help bones heal after back fusion surgery using a rod/screw system. It may help people who have ongoing back or leg pain despite at least 3 months of non-surgical treatments.
Hartford, ConnecticutAges 18 years+ - NCT05066139Recruiting
Study of older adults with digestive cancer
This study checks how well different care plans work for people age 75 and older who have digestive cancer and are about to start chemotherapy or targeted therapy. The goal is to improve treatment support and outcomes by doing a detailed, multidisciplinary evaluation.
StrasbourgAges 75 years+ - NCT05020574RecruitingPhase 2
Study how the microbiome may affect breast implant infections
This Phase 2 study looks at whether changes in the body’s “microbiome” (the normal germs in and on the body) are linked to infections after breast surgery with implants. It may help doctors better predict and prevent implant infections in people undergoing mastectomy with immediate implant placement.
San Francisco, CaliforniaAges 18 years+ - NCT05065151Recruiting
Studying motivation in Parkinson’s using brain stimulation recordings
This study looks at what drives motivation in people with Parkinson’s disease (or dystonia) by using recordings from an implanted brain stimulation device. It may help researchers understand brain signals behind motivation and improve future treatments.
San Francisco, CaliforniaAges 18 years+ - NCT05065060Recruiting
Parkinson study tracking health online and long-term
This study aims to better understand Parkinson’s disease over time by collecting health information online. You may join if you have Parkinson’s, or if you don’t, to compare changes and help researchers find useful markers.
San Francisco, CaliforniaAges 18 years+ - NCT05004987RecruitingPhase 4
Study brain and blood changes in older adults with depression
This study looks at how a brain protein linked to Alzheimer’s disease changes over time in older adults who have major depression but no major memory problems. It involves brain scans, blood and urine tests, and a spinal fluid sample to better understand the connection between depression and brain aging.
New York, New YorkAges 60 years+ - NCT05013892RecruitingPhase 2
Whole-brain radiation with a targeted drug plan for brain mets
This Phase 2 study tests a treatment plan that combines whole-brain radiation therapy with an additional approach to help people with brain metastases. It aims to improve outcomes while also tracking brain function and memory over time.
Boston, MassachusettsAges 18 years+ - NCT05029726RecruitingPhase 4
Numbing medicine during back surgery to reduce pain
This trial tests a regional anesthesia (numbing medicine given near nerves) during minimally invasive lumbar spine surgery. The goal is to see if it helps control pain around surgery and improves recovery comfort.
Chicago, IllinoisAges 18–80 - NCT05039216Recruiting
Biobank for inflammatory arthritis and osteoporosis
This study collects and stores health information and samples for people with long-term inflammatory arthritis (like rheumatoid arthritis, spondyloarthritis, or psoriatic arthritis) or with osteoporosis. It helps researchers understand these conditions and may lead to better future treatments.
ToulouseAges 18–99 - NCT05016219Recruiting
Light therapy to improve sleep and thinking in early Alzheimer’s
This trial studies rhythmic light therapy to help people with early Alzheimer’s or mild memory problems, especially when sleep is getting worse. If you fit the sleep and vision/medical safety requirements, the study may see whether the therapy improves sleep and thinking-related symptoms.
Menands, New YorkAges 55 years+ - NCT05023772Recruiting
Laser and targeted radiation for spine metastases
This trial tests a combination treatment that uses a laser and focused radiation to shrink tumors in the spine and help stabilize the area near the spinal cord. It’s meant for adults with certain types of solid cancers that have limited spread in the spine and who are not good candidates for surgery.
Detroit, MichiganAges 18 years+ - NCT05061368RecruitingPhase 2
Sildenafil by mouth to improve breathing in COPD
This Phase 2 trial tests whether sildenafil tablets can improve exercise ability, shortness of breath, and heart-lung function in people with COPD. It also compares against people without COPD to better understand how sildenafil affects breathing tests.
Edmonton, AlbertaAges 40–80 - NCT05046002Recruiting
COVID vaccine heart inflammation symptom registry
This study is a “registry,” meaning it collects medical information about people who develop possible heart inflammation after a COVID-19 vaccine. It may help doctors understand how often this happens and which findings are linked to it.
Ottawa, OntarioAges 5 years+ - NCT05008081Recruiting
Study for COPD flare-ups given standard rescue medicines
This study looks at people hospitalized for a COPD flare-up (“exacerbation”). It may help improve how flare-ups are treated because participants need to receive the usual rescue medicines like steroids and/or antibiotics and then follow a study plan.
LinzAges 18 years+
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,548 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.