Clinical trials
Glioblastoma - Category clinical trials
Below are recruiting glioblastoma - category clinical trials, each written for real people, not researchers. We’re tracking 357 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03534050RecruitingPhase 2/Phase 3
Testing new radiotherapy outcomes after low-grade brain tumor surgery
This trial studies how patients with grade 2 or 3 low-grade brain gliomas do after modern radiotherapy following surgery (or biopsy). It looks at both brain/memory functioning and cancer outcomes, especially for people at higher risk from their surgery or age.
TaoyuanAges 20–84 - NCT03596086RecruitingPhase 1/Phase 2
Study drug plus radiation and chemo for recurrent brain cancer
This Phase 1/2 study tests whether combining an HSV-tk “gene switch” treatment, valacyclovir tablets, focused radiation (SBRT), and chemotherapy can help people with recurrent glioblastoma or anaplastic astrocytoma. It may help shrink tumors or slow growth after standard treatments have already been tried.
Houston, TexasAges 18 years+ - NCT03603405RecruitingPhase 1/Phase 2
Test vaccine and radiation with chemotherapy for new brain tumor
This trial studies a gene-based treatment (HSV-tk) given with radiation and chemotherapy for people newly diagnosed with glioblastoma or anaplastic astrocytoma. It may help the new brain tumor respond better to standard treatments, though risks and benefits are still being tested.
Houston, TexasAges 18 years+ - NCT03672721RecruitingPhase 1/Phase 2
Carboplatin with radiation for returning glioblastoma
This Phase 1/2 study tests a combination of carboplatin chemotherapy with radiation for glioblastoma that has come back. It aims to shrink or control the tumor after standard treatment has already been used.
Sherbrooke, QuebecAges 18 years+ - NCT03787056Recruiting
Blood test marker study in many cancer types
This study measures a blood marker called progastrin (at diagnosis and during treatment) to see how well it predicts response or outcomes. It may help doctors choose or monitor treatment more precisely for several cancer types.
BronAges 18 years+ - NCT03861299Recruiting
Awake brain surgery versus sleep surgery for glioblastoma
This study compares two ways of doing brain surgery for glioblastoma: doing parts of the operation while you are awake, versus doing it fully under general anesthesia (sleep). It aims to see which approach is safer and better for protecting brain functions like speech and movement while removing the tumor.
GhentAges 18–90 - NCT03896568RecruitingPhase 1
Trial of stem cell therapy for recurrent high-grade brain tumors
This Phase 1 study tests an advanced stem-cell treatment (hMSC-DNX2401) for recurrent high-grade glioma, including certain brain tumor types that come back. It aims to see if the treatment can be safely delivered and whether it can help control the tumor after standard therapies have already been tried.
Houston, TexasAges 18 years+ - NCT03958240Recruiting
Study how cancers trigger the immune system
This study looks at what makes some cancers more “noticeable” to the immune system. It may help researchers design better future immunotherapy by collecting information (often including blood samples) from people with different cancers.
ToulouseAges 18 years+ - NCT03970447RecruitingPhase 2/Phase 3
Testing several treatment options for new or returning glioblastoma
This trial studies different treatment regimens for people with glioblastoma that is either newly diagnosed or has come back. It aims to find which treatment approach works best for controlling the tumor and improving outcomes.
Birmingham, AlabamaAges 18 years+ - NCT03948490Recruiting
Cognitive rehab and follow-up for lower grade brain tumors
This study offers cognitive rehabilitation and long-term monitoring for adults with lower grade gliomas. It aims to help improve thinking and memory problems you may be experiencing.
San Francisco, CaliforniaAges 18 years+ - NCT04047264Recruiting
Testing a brain fluid sampling technique during brain surgery
This study tests whether taking tiny samples of brain fluid during brain tumor or epilepsy surgery is safe and practical. If it works well, it may help doctors better understand brain tissue during surgery.
Rochester, MinnesotaAges 18 years+ - NCT04135807RecruitingEarly Phase 1
Implantable device test for operable brain tumor patients
This early-phase trial tests a tiny implanted device placed during brain tumor surgery. It delivers very small doses of medicine directly to the tumor area for a short time, aiming to see if this approach is safe and workable in patients with certain gliomas.
Boston, MassachusettsAges 18 years+ - NCT04181684Recruiting
Laser surgery plus targeted radiation for recurrent brain gliomas
This trial studies whether a special laser procedure (LITT) followed by focused, reduced-dose radiation can control glioma tumors that have come back. It may help people with recurrent brain tumors avoid or delay more extensive treatment.
Baltimore, MarylandAges 22 years+ - NCT04188535Recruiting
MRI scans during radiation treatment
This study does repeated MRI (detailed brain/body imaging) while you receive radiation therapy. It aims to see how these serial scans relate to treatment and outcomes, which could help improve care planning for different cancers.
Boston, MassachusettsAges 18 years+ - NCT04266977Recruiting
Low-dose steroid timing for newly diagnosed brain tumor surgery
This trial looks at using dexamethasone (a steroid medicine) in a more restricted way for people newly diagnosed with likely glioblastoma who are planned for brain surgery. The goal is to see whether limiting steroid use can still control symptoms while reducing steroid exposure.
Sankt Gallen, St.GallenAges 18–90 - NCT04267978RecruitingPhase 2
Test drug combination for recurrent brain tumor growth
This Phase 2 study tests whether adding recombinant human endostatin to temozolomide and irinotecan can slow or control recurrent gliomas (brain tumors) after prior standard treatment. It may help by targeting tumor blood vessel growth while also using chemotherapy to attack cancer cells.
BeijingAges 18–70 - NCT04306432Recruiting
Check how cognitive tests change after brain tumor radiation
This trial studies how radiation therapy affects thinking and memory in adults with certain brain tumors. It may help doctors understand which patients are more likely to have cognitive side effects and how to measure them over time.
Copenhagen, Capital RegionAges 18–100 - NCT04427384Recruiting
Brain tumor patients treated with GammaTiles registry
This study is a patient registry for people with brain tumors who had surgery to remove as much as safely possible and then had GammaTiles placed. It mainly collects information and follow-up imaging to understand how patients do after the treatment.
Phoenix, ArizonaAges Any age - NCT04443010RecruitingPhase 1/Phase 2
Testing a new protein drug with standard treatment for new glioblastoma
This Phase 1/2 study tests whether adding a drug called L19TNF to standard chemoradiotherapy is safe and may work better than standard treatment alone for newly diagnosed glioblastoma. If you qualify, you would be closely monitored for side effects and treatment response.
ZurichAges 18 years+ - NCT04523688RecruitingPhase 2
Dendritic cell vaccine made from your own tumor cells
This Phase 2 study tests a personalized glioblastoma vaccine made from your own immune cells (collected by apheresis) and your own tumor material. It’s meant to help your immune system recognize and attack the cancer after standard chemotherapy and radiation.
Meldola, FCAges 18 years+ - NCT04541082RecruitingPhase 1
Oral ONC206 for recurrent brain and spinal tumors
This early-phase study tests an oral medicine called ONC206 in adults with recurrent, rare brain or spinal cord tumors. The goal is to find a safe dose and look for signs the treatment can shrink or control the cancer.
Bethesda, MarylandAges 18 years+ - NCT04547777RecruitingPhase 1
Early Phase brain tumor treatment with implanted device and injections
This Phase 1 study tests a new brain-tumor treatment in people with recurrent (coming back) high-grade glioma (brain cancer). The study uses injected medicine along with an implanted tumor device and aims to find whether the treatment is safe and can shrink or control tumors.
Durham, North CarolinaAges 18 years+ - NCT04559230RecruitingPhase 2
Treating recurrent glioblastoma with sacituzumab govitecan
This Phase 2 study tests sacituzumab govitecan in adults whose glioblastoma has come back after standard treatment (radiation plus temozolomide). It may help shrink the tumor in people whose tumor has a specific target (Trop-2).
Cleveland, OhioAges 18 years+ - NCT04573140RecruitingPhase 1
RNA vaccine study for newly diagnosed adult and pediatric brain tumors
This Phase 1 trial studies an “RNA-lipid particle” vaccine given after surgery for certain newly diagnosed brain cancers (glioblastoma in adults, high-grade glioma in children/teens). The goal is to see whether the vaccine is safe and can train the immune system to fight the tumor.
Washington D.C., District of ColumbiaAges 4 years+
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Common questions
- Are there clinical trials for glioblastoma - category?
- Yes. Clin2 currently lists 357 recruiting glioblastoma - category studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glioblastoma - category trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glioblastoma - category trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.