Clinical trials
Glucocorticoid clinical trials
Below are recruiting glucocorticoid clinical trials, each written for real people, not researchers. We’re tracking 49 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05726292RecruitingPhase 2
Enzalutamide plus relacorilant versus placebo for high-risk prostate cancer
This study tests whether adding relacorilant to enzalutamide (a hormone-blocking treatment) helps control high-risk localized prostate cancer better than enzalutamide plus a dummy pill. It may help prevent the cancer from growing or spreading by targeting a hormone pathway in addition to standard treatment.
Chicago, IllinoisAges 18 years+ - NCT05916781RecruitingPhase 4
Lowering steroids with mycophenolate and tacrolimus for lupus kidneys
This study tests whether using mycophenolate mofetil plus tacrolimus can help people with lupus nephritis safely lower (taper) their prednisone to a low dose. It is designed for people whose kidney lupus has been well-controlled for at least 6 months.
BeijingAges 18–65 - NCT06072768RecruitingPhase 2
Testing ways to safely lower steroid doses in rheumatoid arthritis
This study compares two different schedules for reducing prednisone (a steroid) in people with rheumatoid arthritis who are also taking another standard arthritis medicine. The goal is to find the safest and most effective way to taper off steroids without causing a flare-up.
Ann Arbor, MichiganAges 18 years+ - NCT06172361RecruitingPhase 3
Tofacitinib and steroid taper for PMR
This study tests whether a daily pill (tofacitinib) combined with a short course of steroids can help people with active PMR use less steroids over time. You must have high disease activity and not have taken steroids or biologics in the past two weeks.
Hangzhou, ZhejiangAges 50–88 - NCT06430528Recruiting
Osilodrostat and steroid replacement for Cushing syndrome
This trial tests a new approach, called 'block-and-replace', for treating Cushing syndrome. You will take osilodrostat to lower high cortisol levels, along with a glucocorticoid (a steroid) to replace what your body needs. This study may help control the disease if surgery hasn't worked or isn't an option.
Ann Arbor, MichiganAges 18–75 - NCT06496997RecruitingPhase 2/Phase 3
Steroid treatment for acute lung failure (ARDS) trial
This study tests if adding a type of steroid (glucocorticoid) to standard treatment helps people on a breathing machine recover from severe lung failure (ARDS). It compares different doses to see which works best.
Al FayyumAges Any age - NCT06603662RecruitingPhase 4
Steroids for sudden osteoarthritis pain in the emergency room
This trial tests if a short course of oral steroids (glucocorticoids) can relieve sudden osteoarthritis pain in the knee, hip, or shoulder for people who come to the emergency department and are well enough to go home.
York, PennsylvaniaAges 18 years+ - NCT06611696RecruitingPhase 4
Avacopan vs lower-dose steroids for new vasculitis
This study compares a new drug (avacopan) with lower doses of steroids to standard steroid treatment for people newly diagnosed with ANCA-associated vasculitis. The goal is to see if avacopan can control your disease with fewer steroid side effects.
Toyoake, Aichi-kenAges 18 years+ - NCT06663618Recruiting
Steroid and mycophenolate for IgG4-related disease
This trial tests a short course of steroids combined with mycophenolate mofetil (MMF) for people with active IgG4-related disease who have not been treated before or whose disease came back after stopping treatment. The goal is to see if this combination helps control the disease better.
Beijing, Beijing MunicipalityAges 18–80 - NCT06686927RecruitingPhase 2
Steroids, IVIG, and romiplostim for severe ITP
This study tests a combination of three treatments—steroids, IVIG, and romiplostim (Nplate)—for adults with severe, newly diagnosed ITP that hasn't responded well to standard therapy. The goal is to see if this triple therapy can quickly raise platelet counts and stop bleeding.
Wuhan, HubeiAges 18–75 - NCT06689254RecruitingPhase 2
Testing mifepristone for hard-to-treat PTSD in Dutch adults
This study tests a new medicine (mifepristone) to see if it helps people with PTSD that hasn't improved after standard treatments. You must be fluent in Dutch and have tried at least two PTSD treatments, including trauma-focused therapy.
Amsterdam, North HollandAges 18 years+ - NCT06730308RecruitingPhase 2
Steroids with chemoradiation for thymoma that can't be removed
This trial tests if adding a steroid (methylprednisolone) to standard chemotherapy and radiation helps people with thymoma that cannot be fully removed by surgery or has come back. The goal is to see if this combination works better at controlling the disease.
Guanzhou, GuangdongAges 18–75 - NCT06861530Recruiting
Study on adrenal gland recovery after steroid treatment in children with leukemia
This study looks at how the adrenal glands recover after children with leukemia or lymphoma are treated with steroids. The goal is to see how common adrenal suppression is and to help doctors monitor this safely.
AarauAges Up to 18 years - NCT06868290RecruitingPhase 2
CAR-T cell therapy for severe GPA or MPA
This trial tests a new CAR-T cell treatment (rapcabtagene autoleucel) for people with severe active granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA). It aims to see if this therapy can help control the disease by targeting certain immune cells.
Aurora, ColoradoAges 18–75 - NCT06922669Recruiting
Steroids for drug-induced liver injury with high bilirubin
This trial tests whether steroids (glucocorticoids) can help people with acute liver injury caused by a drug, especially when bilirubin levels are high. It aims to see if steroids can reduce liver damage and improve recovery.
Shenyang, LiaoningAges 18–80 - NCT06983821RecruitingPhase 3
Low-dose steroids for kidney disease from vasculitis
This trial tests lower steroid doses for people with certain types of vasculitis that have newly affected their kidneys. The goal is to find out if a lower dose works just as well with fewer side effects.
Hamilton, OntarioAges 18 years+ - NCT06992128RecruitingPhase 2
Romiplostim plus steroids for newly diagnosed ITP
This trial tests a combination of romiplostim (a platelet-boosting drug) and steroids as the first treatment for adults with newly diagnosed immune thrombocytopenia (ITP). It aims to see if this approach can safely and effectively raise platelet counts.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07152340RecruitingPhase 4
Sequential hormone and IBI311 therapy for active TAO
This trial tests a two-step treatment for active, moderate-to-severe thyroid eye disease (TAO). You will first receive hormone therapy, followed by a drug called IBI311. The goal is to see if this sequence works better for people who have not had steroid treatment before.
Changhua, Shanghai MunicipalityAges 18–80 - NCT07206537Recruiting
Vitamin K2 to prevent steroid bone loss in children
This study tests whether vitamin K2 can help prevent bone loss caused by steroid treatment in children with nephrotic syndrome. If your child meets the requirements, taking vitamin K2 may protect their bones while they receive steroids.
CairoAges 1–16 - NCT07213375RecruitingPhase 2/Phase 3
High-dose steroid to reduce pain after lung surgery
This trial tests if a high dose of dexamethasone (a steroid) can lower pain after keyhole lung surgery. If you are having planned keyhole lung surgery for a lobe or segment, you may be eligible.
Copenhagen, CopenhagenAges 18 years+ - NCT07245732RecruitingPhase 4
Steroid pills vs. shots for rheumatoid arthritis flares
This trial compares steroid pills to steroid shots for controlling sudden worsening of rheumatoid arthritis symptoms. It aims to find which method works better and is easier for you.
Toronto, OntarioAges 18 years+ - NCT07340463RecruitingPhase 2
Biologics vs standard therapy for lupus kidney disease
This trial tests two biologic drugs (belimumab or telitacicept) compared to a standard treatment (mycophenolate mofetil) for people with active lupus nephritis. The goal is to see if biologics work better at controlling kidney inflammation over 6 months.
Nanjing, JiangsuAges 14–65 - NCT07478003RecruitingPhase 3
Early steroid for severe heart attacks before reaching the hospital
This study tests whether giving a high dose of a steroid medication (glucocorticoid) early, before reaching the hospital, can help people having a severe type of heart attack called STEMI. If you are having this specific heart attack and meet the criteria, receiving this medication might improve your recovery.
AalborgAges 18 years+ - NCT07547930RecruitingPhase 2
Tofacitinib for Steroid-Resistant Thyroid Eye Disease
This study tests whether tofacitinib, a new type of immune-modulating medication, can help people with moderate-to-severe thyroid eye disease (Graves' orbitopathy) whose eyes haven't improved with standard steroid treatments. The goal is to reduce eye swelling, bulging, and inflammation that affects daily life.
Xiamen, FujianAges 18–75
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Common questions
- Are there clinical trials for glucocorticoid?
- Yes. Clin2 currently lists 49 recruiting glucocorticoid studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glucocorticoid trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glucocorticoid trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.