Clinical trials
Head and Neck Cancer clinical trials
Below are recruiting head and neck cancer clinical trials, each written for real people, not researchers. We’re tracking 620 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07510321Recruiting
A study of FL-261 imaging for cancer diagnosis
This trial tests a new imaging agent called FL-261 to help doctors see and stage cancers more clearly. If you have a known or suspected cancer like lung, colon, or head and neck cancer, this study may improve how your cancer is evaluated.
Wuhan, HubeiAges 18 years+ - NCT07511413Recruiting
Monitoring health in head, neck, lung & rectal cancer
This trial is studying how a monitoring method (bioimpedance) works for people with head and neck, lung, or rectal cancer who are about to start standard treatment. It may help doctors track your health better during therapy.
Candiolo, Torino (TO)Ages 18 years+ - NCT07512921Recruiting
Gene Expression Study for HPV-Negative Head and Neck Cancer
This study compares gene patterns in tumor tissue and blood samples from patients with HPV-negative head and neck cancer. Understanding these patterns may help doctors better understand the disease and develop better treatments.
MilanAges 18 years+ - NCT07514754Recruiting
Immunonutrition support during cancer treatment
This study tests whether special nutritional support (called immunonutrition) helps patients with head and neck, lung, or rectal cancer who are receiving chemotherapy, radiation, or immunotherapy. The goal is to see if it improves how well treatment works and how you feel during and after cancer care.
Candiolo, Torino (TO)Ages 18 years+ - NCT07552467Recruiting
PET Imaging Scan for Detecting Cancer Using New Radioactive Tracer
This study tests a new type of imaging scan (PET/CT or PET/MR) that uses a radioactive tracer to help doctors better detect and diagnose various cancers. The scan targets a specific protein found in tumors, which may help identify cancer more accurately than standard imaging.
Wuhan, HubeiAges 18 years+ - NCT07557225Recruiting
New PET Scan for Detecting Multiple Cancer Types
This study tests a new type of PET scan (a specialized imaging test) that may better detect certain cancers by looking for a specific marker found on many tumor types. The scan uses a new tracer called 18F-T2 to help doctors see cancer more clearly.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07558447Recruiting
Studying Tiny Particles to Predict Chemotherapy Nerve Damage
This study looks at tiny particles in your blood to understand and potentially predict nerve damage caused by certain chemotherapy drugs. Researchers will monitor you before, during, and after your cancer treatment to see if these particles can help warn doctors about this common side effect.
MilanAges 18 years+ - NCT07573956RecruitingPhase 2/Phase 3
Fast versus standard radiation after head and neck cancer surgery
This trial compares two different radiation schedules after surgery for head and neck cancer. One schedule delivers radiation faster over fewer weeks, while the other uses the standard approach. The study tests whether the faster schedule works just as well while potentially reducing side effects.
Jhajjar, HaryanaAges 18–80 - NCT07613723RecruitingPhase 1
Testing ZI-MA4-1 immunotherapy for advanced solid cancers
This early-stage trial tests a new type of immunotherapy called ZI-MA4-1 in patients with advanced cancers (ovarian, lung, synovial sarcoma, or head and neck) that have stopped responding to standard treatments. The therapy is designed to help your immune system recognize and fight cancer cells that have a specific protein called MAGE-A4.
LondonAges 18–75 - NCT07622381Recruiting
Specialist Nurse Care for Head and Neck Cancer Surgery
This trial tests whether extra support from specially trained nurses helps patients recover better after head and neck cancer surgery. The study focuses on improving care, managing side effects, and supporting your overall recovery.
TianjinAges 18–70 - NCT07622914Recruiting
Dietary fiber and muscle health in head and neck cancer
This study tests whether eating more fiber can help prevent muscle loss in people newly diagnosed with head and neck cancer. Researchers will track your nutrition and muscle strength over time to see if dietary fiber makes a difference.
Oklahoma City, OklahomaAges 18 years+ - NCT07625423RecruitingPhase 1
Gene therapy injection for advanced head and neck cancer
This trial tests a new treatment where a specially designed virus carrying an anti-cancer gene is injected directly into tumors in the head and neck area. It's for patients whose cancer has come back or spread after prior chemotherapy and who cannot have surgery or radiation.
Chengdu, ChinaAges 18–65 - NCT07632339RecruitingPhase 2
New drug combination for recurrent head and neck cancer
This trial tests two drugs—becotatug vedotin and pucotenlimab—given before surgery to treat head and neck cancer that has come back in the same area. The goal is to shrink the tumor and help your body's immune system fight the cancer.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07635641Recruiting
Proton Therapy for Recurring Head and Neck Cancer
This study tracks how well proton therapy (a precise radiation treatment) works when head and neck cancer comes back after previous treatment. Proton therapy uses high-energy particles instead of traditional X-rays, which may reduce side effects.
Rozzano, MilanoAges 18 years+ - NCT07662681RecruitingPhase 1/Phase 2
Camrelizumab plus famitinib for rare head and neck cancers
This trial tests a combination of two drugs—camrelizumab (an immunotherapy) and famitinib (a targeted therapy)—for people with rare head and neck tumors that cannot be removed by surgery or have spread. It may be an option if you have not had a prior PD-1 inhibitor and have had at most one prior systemic treatment.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07662746RecruitingPhase 2
Paclitaxel micelles for advanced head and neck cancer
This trial tests a new form of chemotherapy called paclitaxel polymeric micelles for people with head and neck cancer that has come back or spread. It is for patients who have already tried one line of treatment and may benefit from a different option.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07618624Enrolling by invitationPhase 2
Drug combination before surgery for recurrent head and neck cancer
This trial tests three drugs (finotonlimab, cetuximab, and docetaxel) given before surgery to remove recurrent head and neck cancer in patients whose cancer stopped responding to previous immunotherapy. The goal is to shrink the tumor and improve surgical outcomes.
Foshan, GuangdongAges 18–75 - NCT07363031Enrolling by invitationPhase 2
Valacyclovir for mouth sores during head and neck radiation
This trial tests whether the antiviral drug valacyclovir can prevent or reduce painful mouth sores caused by radiation therapy for head and neck cancer.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07218003Enrolling by invitationPhase 1
Study of RNDO-564 alone or with pembrolizumab for bladder cancer
This trial tests an experimental drug, RNDO-564, either by itself or combined with another drug (pembrolizumab), for people with advanced bladder cancer or other solid tumors that have stopped responding to standard treatments. The goal is to see if it can shrink tumors or slow cancer growth.
San Francisco, CaliforniaAges 18 years+ - NCT07051265Enrolling by invitation
Pain relief for head and neck cancer patients using TENS or acupressure
This study compares two non-drug methods—TENS (a mild electrical device) and acupressure (gentle finger pressure on specific points)—to help manage pain in people with head and neck cancer. If you have cancer-related pain and need medication, you may be able to join.
Kaohsiung CityAges 20–100 - NCT06885424Enrolling by invitation
Long-term follow-up for A2 Bio gene therapy patients
This study follows up with people who previously received a gene therapy product from A2 Biotherapeutics in an earlier trial. The goal is to monitor their health over time and check for any long-term effects.
Gilbert, ArizonaAges 18 years+ - NCT06672471Enrolling by invitation
Antibiotics after head and neck surgery study
This trial tests whether giving antibiotics after certain head and neck surgeries helps prevent infections. It is for people having planned (non-emergency) surgery that involves entering a normally clean area that may have some germs, like the mouth or throat.
Lahore, Punjab ProvinceAges 18 years+ - NCT05937269Enrolling by invitationPhase 1
Early physiotherapy to improve lymph swelling after head cancer
This Phase 1 study tests whether starting physiotherapy soon after head and neck cancer treatment can reduce lymph-related swelling problems. It may help your comfort and recovery by improving lymph function using therapy and home compression.
Houston, TexasAges 18 years+ - NCT07195734RecruitingPhase 2
Adding chemo or immunotherapy before surgery for advanced head and neck cancer
This trial tests whether giving chemotherapy or chemotherapy plus immunotherapy before surgery can improve outcomes for people with advanced head and neck cancer that has come back or not gone away after prior treatment.
Tucson, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for head and neck cancer?
- Yes. Clin2 currently lists 620 recruiting head and neck cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a head and neck cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a head and neck cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.