Clinical trials
Heart Failure Patients clinical trials
Below are recruiting heart failure patients clinical trials, each written for real people, not researchers. We’re tracking 765 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05370014Recruiting
Partner support program for chronic health conditions
This study tests a program that helps patients with chronic health conditions and their care partners work together to improve their health and well-being. If you live in a rural or underserved area in South Carolina and have a condition like diabetes or high blood pressure, you and your support person might be able to join.
Columbia, South CarolinaAges 18 years+ - NCT05279742Enrolling by invitationPhase 1/Phase 2
Study drug to boost a hormone system in HFpEF
This early-phase trial tests a treatment that aims to improve the “natriuretic peptide” hormone system in people with HFpEF (heart failure with preserved pumping strength). It may help reduce symptoms and improve heart and fluid pressure behavior, especially in certain related conditions like kidney disease.
Rochester, MinnesotaAges 18 years+ - NCT05230745Recruiting
Test device for heart failure safety and how well it works
This trial studies whether the ContraBand device can be safely placed in people with long-term, symptomatic heart failure and reduced heart pumping. It also looks at whether the approach is practical and tolerable, and gathers early safety information.
AalstAges 18–85 - NCT05230732Recruiting
Test a nerve-stimulation approach for heart inflammation
This trial studies a nerve-stimulation treatment to affect inflammation and blood vessel function in people with systolic heart failure. If you qualify, it may help improve how your heart and blood vessels work.
Oklahoma City, OklahomaAges 18–85 - NCT04984473Recruiting
Breathing muscle training during heart rehab
This study tests whether breathing muscle training, added to regular heart rehab, can improve how well people with heart failure do day-to-day. It also compares results with healthy volunteers who do not have certain health problems.
Rochester, MinnesotaAges 18 years+ - NCT04600115RecruitingEarly Phase 1
New MRI methods for heart failure with preserved pumping function
This study tests advanced MRI techniques to better understand heart failure with preserved ejection fraction (HFpEF), a condition where the heart pumps normally but still doesn't work well. It may help improve diagnosis and treatment for patients with this type of heart failure.
Salt Lake City, UtahAges 18 years+ - NCT04676100Enrolling by invitation
International registry for cardiac rehabilitation programs
This study collects information about cardiac rehabilitation (CR) programs in lower-resource areas. It helps improve how CR is delivered and understood, especially where healthcare resources and awareness are limited.
DohaAges 18 years+ - NCT04592445Recruiting
Nerve ablation for right-sided symptoms in HFpEF heart failure
This trial tests a procedure to “turn off” the right greater splanchnic nerve to improve symptoms in people with HFpEF (heart failure with preserved pumping function). If successful, it may reduce shortness of breath and fluid congestion in daily life.
Birmingham, AlabamaAges 40 years+ - NCT04493385Recruiting
Heart transplant after a hepatitis C–positive donor
This trial follows people who receive a heart from a donor whose blood tested positive for hepatitis C. It also includes people getting a heart transplant again, and it aims to learn about outcomes and safety for these specific transplant situations.
Dallas, TexasAges 18 years+ - NCT04419480Recruiting
Monitoring to help prevent complications after cardiogenic shock
This study tests a special monitoring approach (likely using an implanted device) to help prevent serious complications after you survive cardiogenic shock in the hospital. It may help the care team detect problems earlier so treatments can start sooner.
Falls Church, VirginiaAges 18 years+ - NCT04347655Recruiting
Studies blood flow and heart pumping in adults with heart failure
This study looks at how well blood moves through the body and how strongly the left side of the heart pumps in adults. It compares people who have heart failure to people who do not, to better understand differences and possible causes.
Calgary, AlbertaAges 18 years+ - NCT04323371Recruiting
Study testing for heart-shock to reduce future events
This trial studies how to identify different types of “cardiogenic shock,” a serious drop in heart blood flow. It aims to use detailed patient information to guide care and possibly lower the chance of dangerous outcomes.
MilanAges 18–74 - NCT00733590Recruiting
Study after ICD generator replacement for heart attack patients
This study follows people who had a prior heart attack and later received a replacement ICD (a device that helps prevent sudden dangerous heart rhythms). It is observational, meaning it mainly looks at outcomes and device-related information rather than testing a new drug.
Washington D.C., District of ColumbiaAges 18–85 - NCT03876223Recruiting
Testing imaging to study heart symptoms without blocked arteries
This trial studies people who have heart-related symptoms but do not have clear blocked heart arteries, using special heart imaging. It may help researchers better understand early forms of heart weakness (with preserved pumping function) and improve how these conditions are diagnosed.
Los Angeles, CaliforniaAges 18 years+ - NCT03854071Recruiting
Heart and health MRI testing in healthy people or patients
This study uses MRI (a scanning test) to develop new ways to measure heart function in both healthy volunteers and people with suspected or known heart disease. It may help researchers create better heart tests that could improve future diagnosis and monitoring.
Sheffield, EnglandAges 20–80 - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT02683681Enrolling by invitation
Create a heart tissue and blood sample registry
This study collects blood and/or heart tissue samples from certain people getting heart procedures or with a long-term heart pump. The goal is to store these samples for future research that may improve care for heart failure.
Ages 18 years+ - NCT02966665RecruitingPhase 1
Testing blood vessel function in people of different health conditions
This early study measures how well your blood vessels work using tests that may include MRI. It compares healthy people with people who have conditions like COPD, pulmonary arterial hypertension, heart failure, or high blood pressure, to better understand “vascular function” in health and disease.
Salt Lake City, UtahAges 18 years+ - NCT02306200Recruiting
A study to improve heart and aorta health
This trial looks at ways to improve cardiovascular (heart and blood vessel) health, especially conditions that affect the aorta, such as aneurysms, or vascular problems that may run in families. If you have an aortic-related or other cardiovascular diagnosis (or you’re a healthy comparison participant), you may be invited to take part in this health-improvement program.
Ann Arbor, MichiganAges Any age - NCT01790152Recruiting
Dexrazoxane study to monitor heart damage in cancer survivors
This study tests dexrazoxane (DRZ) to see how it affects blood and heart-related “biomarkers,” or measurable signs of heart damage, after cancer treatment. It mainly targets survivors who may be at risk for cardiomyopathy (heart muscle weakness) or related heart failure.
Birmingham, AlabamaAges Any age - NCT07867457Recruiting
Breathing exercises to improve oxygen levels and heart rate after stent placement
This study compares two breathing exercises—alternate nostril breathing and diaphragmatic (belly) breathing—to see which is better at improving oxygen levels and heart rate stability in people who recently had a stent placed in their heart arteries.
RawalpindiAges 44–75 - NCT06749951Recruiting
Talk therapy for insomnia in heart disease patients
This study tests whether cognitive behavioral therapy (a type of talk therapy focused on changing thoughts and habits) can help people with coronary heart disease who also have trouble sleeping. You will learn skills to improve your sleep and your overall heart health.
Drammen, BuskerudAges 18–75 - NCT07157696Recruiting
Advanced oxygen monitoring for chronic lung or heart disease
This study tests a more advanced way to monitor oxygen levels and deliver oxygen therapy at home for people with chronic lung or heart conditions who have acute breathing problems. It aims to see if this approach improves care and quality of life.
Ferrara, ItalyAges 18–80 - NCT06676696RecruitingPhase 4
Stopping immunosuppression after failed kidney transplant
This study compares what happens when patients with a failed kidney transplant (still in the body) stop their immunosuppressant medicines at 6 months versus continuing them. The goal is to safely prevent your immune system from becoming too sensitive, which can make finding a new donor kidney harder.
BarcelonaAges 18 years+
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Common questions
- Are there clinical trials for heart failure patients?
- Yes. Clin2 currently lists 765 recruiting heart failure patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.