Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06763549Enrolling by invitation
AI-powered wearable patch for heart and lung monitoring
This study tests an AI-powered wearable patch (the COR ECG) to see if it can better track heart and lung health. It may help doctors find problems earlier without needing bulky equipment.
Melbourne, FloridaAges 18 years+ - NCT06361524Enrolling by invitation
Gut bacteria study in chronic heart failure
This study looks at the bacteria in your gut (your 'gut microbiome') and how it relates to chronic heart failure. It may help doctors understand why some people with heart failure do better than others and could lead to better treatments in the future.
Stanford, CaliforniaAges 18–75 - NCT06299176Enrolling by invitationPhase 1
Whole-heart radiation therapy for advanced heart failure
This trial tests if a low dose of radiation to the whole heart can help people with very advanced heart failure. It is for people who have severe symptoms despite maximum medications and are not candidates for a heart pump or transplant.
Montreal, QuebecAges 65 years+ - NCT06065761Enrolling by invitation
Better risk assessment for heart failure in the ER
This trial looks at ways to better understand how serious heart failure is for people who come to the emergency room. It could help doctors decide on the best treatment more quickly.
Antioch, CaliforniaAges 18 years+ - NCT05610787Enrolling by invitation
Testing a device that helps move an EXCOR pediatric heart pump
This trial studies an “active driving” system that controls the EXCOR pediatric heart pump. It’s meant for children who need a heart pump as a bridge to heart transplantation, to help the pump work more safely and effectively.
Los Angeles, CaliforniaAges Up to 21 years - NCT06844006Enrolling by invitation
How nudges help doctors prescribe heart failure medications
This study looks at whether gentle reminders (nudges) can help doctors prescribe the right heart failure medications. It aims to improve treatment for people with heart failure.
Eindhoven, North BrabantAges 18 years+ - NCT07397650RecruitingPhase 4
Early finerenone for heart failure in hospital
This trial tests if starting finerenone early helps patients hospitalized with heart failure who have symptoms like shortness of breath or swelling. It aims to see if the drug is safe and effective when given soon after admission.
Handa, Aichi-kenAges 18 years+ - NCT05724433Recruiting
Virtual care after heart failure hospitalization
This trial tests whether a home, virtual-care program after a recent heart failure hospital visit can improve recovery and outcomes. You may be invited if you recently left the hospital for heart failure and meet specific heart and lab test thresholds.
Hamilton, OnatrioAges 18 years+ - NCT03806972Recruiting
Study outcomes after emergency heart failure admission
This study follows people admitted to the emergency department for acute heart failure to understand their short- and long-term outcomes. It may help doctors predict who needs more support and improve follow-up after discharge.
Monastir, Monastir GovernorateAges 18–80 - NCT07506499Recruiting
Cardiac Rehab for Hospitalized Heart Failure Patients
This study tests whether a cardiac rehabilitation program (a supervised exercise and education plan) helps people recovering in the hospital from severe heart failure. It is for those aged 45–65 whose heart pumps less than 40% of its normal amount.
Banī Suwayf, Beni-Suef GovernorateAges 45–65 - NCT06967441Recruiting
Respiratory viruses and acute heart failure study
This trial looks at whether a respiratory virus might be triggering your heart failure. It will test your nasal swab for viruses to help doctors understand and treat your condition better.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06514820Recruiting
Exercise MRI study for obesity-related heart failure
This study uses an exercise test with MRI to understand how obesity affects the heart in people with heart failure. It aims to find better ways to diagnose and help patients.
GroningenAges 18 years+ - NCT06783166RecruitingPhase 2/Phase 3
Comparing two medications for acute heart failure with fluid buildup
This trial tests if dapagliflozin or acetazolamide works better for people hospitalized with heart failure who have extra fluid in their body (congestion). The study will compare how well each medication helps remove fluid when used with standard IV diuretics.
Al MansurahAges 18 years+ - NCT05392764RecruitingPhase 3
SGLT2 medicine for high-risk people after sudden worsening heart failure
This Phase 3 trial tests whether starting an SGLT2 inhibitor early in the hospital can improve outcomes for people at high risk after acute (sudden) heart failure. If you qualify, you would be randomized to receive the study medicine or standard care, started within 12 hours of admission.
Anjo, Aichi-kenAges 20 years+ - NCT02444416Recruiting
Registry study for people with new acute heart failure
This study is a registry that collects information about people who come to care with sudden (acute) worsening heart failure symptoms. If your test shows a higher BNP level, your doctors may use your details to better understand and track acute heart failure care.
GenevaAges 16–100 - NCT05966415RecruitingPhase 2
Endocalyx for heart failure with fluid overload
This Phase 2 study tests Endocalyx to treat people with heart failure who currently show signs of fluid buildup (congestion). If you qualify, you may help researchers see whether this supplement can improve symptoms and heart-failure–related measurements.
Amsterdam, North HollandAges 18–110 - NCT07101289Recruiting
Eat Well Heart Failure Coaching Study
This study is testing a virtual health coaching program that helps people with heart failure eat better when they have trouble affording food. The program may help prevent future hospital stays and improve your health.
Durham, North CarolinaAges 18 years+ - NCT07335510Recruiting
Baroreflex therapy for heart failure patients
This trial tests a device that stimulates a nerve in your neck to help your heart pump better. It is for people with heart failure and a weak heart pump who still have symptoms despite taking medications.
San Francisco, CaliforniaAges 18 years+ - NCT06977477Recruiting
Managing fluid buildup in heart failure patients
This study tests a new way to manage fluid buildup in patients with a specific type of heart failure (HFpEF) who are in the hospital. It aims to improve how doctors remove excess fluid and help you feel better.
Magdeburg, Saxony-AnhaltAges 18 years+ - NCT07400991Recruiting
Restrictive vs liberal fluids for hospitalized heart failure
This trial studies whether drinking less fluid (restrictive) vs. the usual amount (liberal) helps people hospitalized with heart failure. It aims to find out which approach leads to better recovery and fewer symptoms.
HerningAges 18 years+ - NCT05802849RecruitingPhase 4
Oral acetazolamide for worsening heart failure
This trial tests whether taking acetazolamide by mouth can help prevent or improve worsening (decompensation) of heart failure after you needed IV water pills (diuretics). It’s mainly for adults with a recent heart-failure flare and specific heart/lab signs, while carefully excluding certain low blood pressure, kidney issues, and electrolyte or acid–base problems.
SamaraAges 18 years+ - NCT07325942Recruiting
Low vs high volume high-intensity interval training for heart failure
This study compares two different types of high-intensity interval exercise programs (one shorter, one longer) in people with chronic heart failure. It aims to see which program improves heart health and daily function more.
Cairo, Giza GovernorateAges 18 years+ - NCT06587854Recruiting
Study on fluid congestion in acute heart failure patients
This study looks at different patterns of fluid buildup in people with acute heart failure. It aims to understand how these patterns relate to treatment with water pills (diuretics) and may help improve care.
GroningenAges 18 years+ - NCT07657650Recruiting
Imaging test for heart failure patients before revascularization
This trial uses a special imaging scan to see if heart muscle has damage from blocked arteries. It helps doctors decide if a procedure to open blocked arteries might improve your heart function.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 981 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.