Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06036615Recruiting
Exercise training for frailty and fall risk in heart failure
This trial tests whether a supervised exercise program can reduce frailty and fall risk in people with chronic heart failure, and what happens when training stops. It may help you feel stronger and more stable.
Thessaloniki, ThermiAges 18–100 - NCT07577596RecruitingPhase 4
Continuous Furosemide Infusion for Heart Failure Fluid Overload
This study tests whether giving furosemide (a water pill) as a continuous IV drip works better than standard doses for patients hospitalized with heart failure and fluid buildup. The goal is to help your body get rid of excess fluid more effectively.
RandersAges 18 years+ - NCT07704424Recruiting
Testing a heart pump for severe right heart failure
This trial is evaluating a new temporary heart pump called CorVad for people who develop severe right heart failure shortly after heart surgery, a heart attack, or a heart transplant. The pump is designed to help the right side of the heart pump blood when medications are not enough.
Hefei, AnhuiAges 18 years+ - NCT03142659Recruiting
Heart failure care evaluation for adults at this clinic
This study looks at how people with heart failure are evaluated and managed in the clinic. It mainly involves follow-up care and documenting your treatment plans to improve how care is delivered.
Tel AvivAges 18–120 - NCT04405583Recruiting
Follow-up study for a heart device in heart failure patients
This study follows people with chronic heart failure to see how well an implanted device (called the Occlutech AFR) works and whether it is safe over time. It may help doctors better understand who benefits and how to manage treatment safely.
BesançonAges 18 years+ - NCT04656080Recruiting
Test heart and lung exercise capacity after transplant
This study uses a treadmill or stationary bike test to measure how well your heart and lungs work after a heart transplant. It may help researchers see whether this type of testing is safe and useful in transplant follow-up.
Dallas, TexasAges 18 years+ - NCT05230784Recruiting
Air purifier study for people with heart failure
This trial tests whether using air purifiers can help people with heart failure breathe better and feel better. It enrolls adults with recent heart failure and specific heart and lung conditions, while avoiding people with certain severe breathing problems or recent heart device treatment.
Thiruvananthapuram, KeralaAges 18 years+ - NCT05486000Recruiting
Testing a device to help chronic left heart failure
This trial studies a small implant (an “atrial shunt” device) to improve symptoms and heart function in people with chronic left heart failure that stays active despite standard medicines. It focuses on whether the implant is safe and can help you feel better and possibly breathe easier.
Nantong, JiangsuAges 18 years+ - NCT05537467Recruiting
Music during exercise for people with heart failure
This trial tests whether listening to music while you exercise can improve how well you can exercise when you have heart failure. It is mainly looking for adults who can safely do an exercise test and communicate in English.
Lexington, KentuckyAges 18 years+ - NCT05769036Recruiting
Biventricular vs left bundle pacing for heart failure outcomes
This trial compares two types of heart pacing to see which improves outcomes for people with heart failure. It may help those who need pacing to better coordinate heartbeats and relieve symptoms.
TomskAges 18–80 - NCT05936957Recruiting
Heart failure care study for acute and chronic patients
This study welcomes people with heart failure (both sudden/worsening and long-term). It will check how heart failure care is managed, and it only moves forward if you choose to participate.
Ibadan, Oyo StateAges 18–100 - NCT06009276Recruiting
Gut bacteria, muscle blood flow, and fitness study
This study looks at how the bacteria in your gut affect blood flow to your muscles and your overall fitness. You will provide samples and do some exercise tests to help researchers understand this link.
Charlottesville, VirginiaAges 18 years+ - NCT06092437Recruiting
Testing a personalized diuretic plan for acute heart failure
This trial is testing whether a diuretic (water pill) dose tailored to each patient works better for treating fluid buildup during a heart failure flare-up. It may help you get the right amount of medication faster and avoid complications.
Heerlen, LimburgAges 18 years+ - NCT06099158Recruiting
Heart failure trial guided by HeartLogic technology
This trial tests if using HeartLogic, a feature in your heart device that tracks early warning signs, can help your care team manage your heart failure better and keep you out of the hospital. If you already have a compatible CRT-D or ICD and use remote monitoring, you may be able to join.
Hellerup, Capital RegionAges 18 years+ - NCT06101693Recruiting
Biomarker study for suspected heart failure
This study looks at certain proteins in your blood to help doctors better understand and diagnose a type of heart failure called HFpEF. You might be able to join if your doctor recently ordered a blood test for NT-proBNP because they thought you might have heart failure.
GlasgowAges 18 years+ - NCT06161402Recruiting
Elastic band exercise for muscle loss in heart failure patients
This trial tests whether a simple at-home exercise program using elastic bands can help older adults with heart failure who also have muscle weakness or low muscle mass (sarcopenia). The goal is to improve strength and daily function.
Hong KongAges 50 years+ - NCT06222099Recruiting
Heartfelt study for chronic heart failure with swelling and adherence challenges
This trial tests a program to help people with chronic heart failure who have swelling in their feet and legs and struggle to follow their care plan. It aims to reduce hospital visits by improving daily monitoring and medication use.
Little Rock, ArkansasAges 22 years+ - NCT06270498RecruitingPhase 4
Oral iron for heart failure: exercise and quality of life study
This study tests whether an oral iron supplement (a pill called sucrosomial iron) can help people with heart failure who have low iron feel better, have more energy, and walk farther. Participants will take the iron pill or a placebo (a pill without the active ingredient) for a period and will do exercise tests and answer questionnaires to see how they improve.
Pisa, TuscanyAges 18 years+ - NCT06283420Recruiting
Metabolic Effects of Starting Heart Failure Therapies
This trial looks at how starting new heart failure treatments affects your body's metabolism. It may be an option if you have stable heart failure and haven't taken certain newer medicines before.
PragueAges 18 years+ - NCT07695090RecruitingPhase 2
Lumacaftor for improved brain blood flow in heart failure
This trial tests if lumacaftor, a medication used in cystic fibrosis, can improve blood flow to the brain in people with stable heart failure. It might help if you have heart failure with reduced pumping function and low brain blood flow.
Toronto, OntarioAges 18 years+ - NCT06338878Recruiting
Heart failure hospitalization study: tracking long-term outcomes
This study looks at what happens to people after they are hospitalized for heart failure. It tracks their health both in the hospital and after they go home to learn how to improve care.
NancyAges 18 years+ - NCT06350695Recruiting
Compression stockings for heart failure with leg swelling
This trial tests whether wearing compression stockings can help people with heart failure who have leg swelling. Researchers want to see if stockings reduce fluid buildup and improve daily life.
Dallas, TexasAges 18 years+ - NCT06364644Recruiting
Reducing heart failure risk in low-income adults with diabetes
This study looks at how low income and diabetes together raise the risk of heart failure. It offers a program to help you manage your health and reduce that risk.
Baltimore, MarylandAges 30–70 - NCT06425848Recruiting
Heart failure monitoring study
This study looks at how a small monitor inside the blood vessel to the lungs helps manage heart failure. It aims to improve care for people with advanced heart failure.
La Jolla, CaliforniaAges 18–100
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 981 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.