Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07451457Recruiting
Structured education program for heart failure patients
This trial tests if a structured education program helps people with heart failure manage their condition better. If you have been hospitalized for heart failure or are treated at a heart failure clinic, you may be able to join and learn more about your care.
BudapestAges 18 years+ - NCT07460531Recruiting
Physical activity and heart health in chronic heart failure
This study looks at how physical activity affects heart outcomes in people with chronic heart failure. If you have a pedometer or activity tracker, you may be able to join.
Munich, BavariaAges 18 years+ - NCT07472660Recruiting
Web-based prevention program after heart failure hospitalization
This trial tests a web-based prevention program for people recently hospitalized with heart failure (with low pumping ability). The goal is to help you stay healthier and avoid another hospital stay.
BremenAges 18–80 - NCT07484009Recruiting
ReDS-guided fluid removal for heart failure patients
This trial tests if using a wearable monitor (ReDS) to guide fluid removal helps people hospitalized for heart failure. The goal is to find the right amount of fluid to remove so patients feel better and stay out of the hospital.
Madrid, MadridAges 18 years+ - NCT07508891Recruiting
Studying heart failure types in hospitalized patients
This trial looks at different types of acute heart failure in people who are hospitalized. Doctors will study your symptoms and health to better understand heart failure patterns, which might help improve future treatments.
HamburgAges 18 years+ - NCT07513883RecruitingPhase 4
Reducing Heart Failure Medications When Your Heart Recovers
This study tests whether patients whose heart failure has improved can safely reduce some of their medications. If your heart function has recovered significantly and stayed stable, this trial explores whether you can gradually lower doses of heart failure drugs while staying healthy.
GenkAges 18 years+ - NCT07527156RecruitingPhase 4
Ketones through a nose tube for severe heart failure
This trial tests whether giving a special liquid diet (ketones) through a thin tube in your nose helps your heart pump better when it's severely weakened and not getting enough blood to your body. Ketones are an alternative fuel your body can use instead of glucose.
Prague, PragueAges 18 years+ - NCT07530029Recruiting
Muscle loss in older patients with heart failure
This study looks at muscle loss (sarcopenia) in older patients (80+) hospitalized for heart failure with preserved pumping function. It may help doctors better understand how to care for this specific group.
Madrid, MadridAges 80 years+ - NCT07543562RecruitingPhase 3
Selenium supplement for heart failure patients
This study tests whether taking selenium (a mineral supplement) helps heart failure patients feel better and live longer. Researchers will follow patients over time to see if selenium reduces symptoms and hospital visits.
OsloAges 18 years+ - NCT07544771Recruiting
HeartLogic monitoring in heart failure patients
This study tests whether a special monitoring system in your heart device (called HeartLogic) can help detect early warning signs of heart failure getting worse. It uses wireless check-ins to track your condition at home and alert your doctor if you need help.
AmiensAges 18 years+ - NCT07560592Recruiting
Salt Intake Study for Recently Hospitalized Heart Failure
This study looks at how salt intake affects people who were just admitted to the hospital with heart failure. Researchers want to understand if managing salt differently can help your heart work better and prevent future hospitalizations.
New Brunswick, New JerseyAges 18 years+ - NCT07601724Recruiting
How fluid buildup affects sleep apnea in heart failure
This study looks at how excess fluid in the body affects sleep apnea (pauses in breathing during sleep) in people hospitalized with heart failure. Researchers will measure sleep apnea before and after treatment to reduce the fluid, which may help doctors better manage both conditions together.
JerusalemAges 18 years+ - NCT07649148Recruiting
Tracking What You Eat to Help Your Heart
This study asks people with moderate heart failure to use a food-tracking app and work with a coach to eat fewer ultra-processed foods. Researchers want to see if changing your diet this way can improve how you feel and how well your heart works.
Cleveland, OhioAges 18 years+ - NCT07671742Recruiting
Monitoring heart failure without needles in the hospital
This study tests a new device that checks your heart without needles while you are in the hospital for heart failure. It may replace some blood tests and help doctors make treatment decisions more easily.
LundAges 18 years+ - NCT07442448Enrolling by invitationPhase 4
Study of Finerenone for heart and kidney health in diabetes
This trial tests a medication called Finerenone to see if it can improve heart structure and function in people with both diabetic kidney disease and heart failure. If you have type 2 diabetes, kidney problems, and heart failure with preserved pumping function, this study may explore a new treatment option for you.
TaipeiAges 18 years+ - NCT07317882Enrolling by invitation
Video education program for heart failure
This trial will test a remote education program for people with heart failure. You'll get video calls and learning materials to help manage your condition from home.
Cadiz, CádizAges 18 years+ - NCT07298993Enrolling by invitationPhase 4
Can older adults with heart failure safely stop beta-blockers?
This trial tests whether it is safe to gradually stop beta-blocker medication in older adults with heart failure with preserved ejection fraction (a type of heart failure where the heart pumps normally but is stiff). It aims to improve quality of life by reducing unnecessary medications.
Pleasanton, CaliforniaAges 60 years+ - NCT07253909Enrolling by invitation
Arm function in heart failure with ICD or CRT devices
This study looks at how well people with heart failure and certain heart devices (ICD or CRT) can use their arms and hands. It aims to understand if these devices affect upper body function.
Ankara, SamanpazarıAges 18 years+ - NCT07252310Enrolling by invitationPhase 4
Smartphone app to find best beta blocker dose for heart failure
This study uses a smartphone app to test how different beta blocker doses work best for you. It's for older adults with stable heart failure who want to fine-tune their treatment.
New York, New YorkAges 65 years+ - NCT07243119Enrolling by invitationPhase 4
Heart failure study with adenosine scans to predict recovery
This trial tests whether high-dose adenosine during a heart scan can better predict how well your heart muscle might recover, compared to standard dosing. The information could help doctors personalize treatment for people newly diagnosed with heart failure and a low ejection fraction.
HerningAges 18–100 - NCT07204834Enrolling by invitation
Physical activity program for heart failure
This study tests a home-based physical activity program for people with heart failure. The program is designed to be safe and easy to follow, using a smartphone app to guide you, and may help you feel stronger and more active.
GranadaAges 18 years+ - NCT07050706Enrolling by invitation
Heart failure and protein levels in the blood
This trial checks if a protein called PRMT5 in the blood is linked to heart function in people with heart failure. It compares healthy volunteers and those with heart failure to see if this protein can help understand the condition better.
Shenzhen, GuangdongAges 18 years+ - NCT06999369Enrolling by invitation
Heart failure nutrition app study
This study tests a digital nutrition tool to help people with heart failure improve their health. It is for patients recently hospitalized or seeing their doctor regularly.
Walnut Creek, CaliforniaAges 18–89 - NCT06937320Enrolling by invitationPhase 2
Testing ketone supplements for heart failure with preserved ejection fraction (HFpEF)
This study tests whether a special dietary supplement (ketone esters) can improve exercise ability and heart function in people with a type of heart failure where the heart pumps well but is stiff (HFpEF). You might join if you have stable symptoms, an ejection fraction of 50% or higher, and signs of fluid buildup in the heart.
Durham, North CarolinaAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 981 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.