Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02973633RecruitingEarly Phase 1
Heart failure MRI brain-wave images after heart trouble
This early-phase study uses a special MRI scan to look at the heart in people with heart failure (and related heart changes). It aims to see whether these MRI results can better characterize heart disease and help doctors understand what’s going on.
Charlestown, MassachusettsAges 18–85 - NCT05086978Enrolling by invitation
Retina camera test in people with heart failure
This study uses a simple camera to take pictures of the back of your eye (retina) to see how useful retinal imaging might be in people with heart failure. You may also be invited as a healthy control, depending on the group you belong to.
Cleveland, OhioAges 18 years+ - NCT05064709Recruiting
Test device for heart failure symptoms in some patients
This study tests whether a heart-related device called CCM can improve symptoms and daily function in people with heart failure and a moderately reduced pumping strength. It may help if you’ve had recent heart-failure-related hospital care or urgent treatment and your heart and overall health fit the study limits.
Birmingham, AlabamaAges 18 years+ - NCT04829617Recruiting
Program to improve daily habits in heart failure
This trial studies a program designed to help people with heart failure improve health habits like diet, exercise, and taking medicines. It may help you feel better and stay on track if your current routines are hard to follow.
Boston, MassachusettsAges 18 years+ - NCT04396899RecruitingPhase 1/Phase 2
Stem cell heart patch for advanced heart failure
This early-phase study tests a lab-made heart tissue (“engineered myocardium”) placed surgically to help the heart work better in people with advanced heart failure. It mainly checks safety first, and also looks for signs the patch can improve heart function in selected patients.
Göttingen, Lower SaxonyAges 18–80 - NCT04237701Recruiting
Tracking heart failure in real time at Yale
This trial looks at how people with heart failure are doing using real-time monitoring across the Yale New Haven Health System. It may help improve care by spotting problems sooner and tracking treatment effects.
New Haven, ConnecticutAges 18 years+ - NCT03999138Recruiting
MRI study of lung fluid changes in acute heart failure
This study uses MRI scans to measure lung fluid (pulmonary edema) in people hospitalized for acute heart failure. It aims to see how well the lung fluid responds to standard treatments like water pills (diuretics) given in the first couple of days.
Edmonton, AlbertaAges 18 years+ - NCT03775577Recruiting
Exercise testing study for people with heart failure
This study looks at exercise intolerance in heart failure, using heart and lung tests to understand how symptoms affect activity. It may help researchers better identify what limits exercise and how heart failure impacts quality of life.
Baltimore, MarylandAges 21 years+ - NCT03586336Recruiting
Remote lung fluid monitoring to guide heart failure treatment
This study tests a wearable vest that measures fluid in your lungs to help doctors adjust water-pill treatments for heart failure. It aims to reduce hospital stay and improve recovery.
San Francisco, CaliforniaAges 18 years+ - NCT03480633Recruiting
Heart failure precision medicine registry
This registry collects health and heart-related information to better understand heart failure (with preserved or reduced pumping strength) and guide more precise care. You may be asked to share tests and results, and help researchers learn which patterns match different types of heart failure.
Boston, MassachusettsAges 18 years+ - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT03103932Recruiting
Blood test–guided discharge for people hospitalized with heart failure
This trial checks whether using a blood test (a “biomarker”) can help doctors decide when it’s safe to send people home after a hospital stay for worsening heart failure. It may help reduce avoidable readmissions while keeping you safe.
Ottawa, OntarioAges 18 years+ - NCT02368041Recruiting
Near-infrared scan test in children with heart failure
This study tests whether a near-infrared “light scan” on the hand can help doctors in children with heart failure who are stable on their usual medications. It may give additional information about blood flow and circulation in the body without using invasive procedures.
Gainesville, FloridaAges Up to 25 years - NCT00762008Recruiting
Test blood markers to understand progression to heart failure
This study looks at blood “markers” (substances in the blood) to help explain how some people move from early heart strain to full heart failure. You may be enrolled if you have stable or worsening heart failure symptoms, or you may qualify as a healthy control for comparison.
Farmington, ConnecticutAges 18 years+ - NCT07575672RecruitingPhase 3
Finerenone after heart valve replacement
This study tests if the drug finerenone helps people with heart failure who had a heart valve replacement (TAVI) for severe aortic stenosis. The goal is to see if it improves heart function and outcomes.
Bengbu, AnhuiAges 65 years+ - NCT03142659Recruiting
Heart failure care evaluation for adults at this clinic
This study looks at how people with heart failure are evaluated and managed in the clinic. It mainly involves follow-up care and documenting your treatment plans to improve how care is delivered.
Tel AvivAges 18–120 - NCT05486000Recruiting
Testing a device to help chronic left heart failure
This trial studies a small implant (an “atrial shunt” device) to improve symptoms and heart function in people with chronic left heart failure that stays active despite standard medicines. It focuses on whether the implant is safe and can help you feel better and possibly breathe easier.
Nantong, JiangsuAges 18 years+ - NCT02444416Recruiting
Registry study for people with new acute heart failure
This study is a registry that collects information about people who come to care with sudden (acute) worsening heart failure symptoms. If your test shows a higher BNP level, your doctors may use your details to better understand and track acute heart failure care.
GenevaAges 16–100 - NCT05936957Recruiting
Heart failure care study for acute and chronic patients
This study welcomes people with heart failure (both sudden/worsening and long-term). It will check how heart failure care is managed, and it only moves forward if you choose to participate.
Ibadan, Oyo StateAges 18–100 - NCT06338878Recruiting
Heart failure hospitalization study: tracking long-term outcomes
This study looks at what happens to people after they are hospitalized for heart failure. It tracks their health both in the hospital and after they go home to learn how to improve care.
NancyAges 18 years+ - NCT06425848Recruiting
Heart failure monitoring study
This study looks at how a small monitor inside the blood vessel to the lungs helps manage heart failure. It aims to improve care for people with advanced heart failure.
La Jolla, CaliforniaAges 18–100 - NCT06283420Recruiting
Metabolic Effects of Starting Heart Failure Therapies
This trial looks at how starting new heart failure treatments affects your body's metabolism. It may be an option if you have stable heart failure and haven't taken certain newer medicines before.
PragueAges 18 years+ - NCT07704424Recruiting
Testing a heart pump for severe right heart failure
This trial is evaluating a new temporary heart pump called CorVad for people who develop severe right heart failure shortly after heart surgery, a heart attack, or a heart transplant. The pump is designed to help the right side of the heart pump blood when medications are not enough.
Hefei, AnhuiAges 18 years+ - NCT07695090RecruitingPhase 2
Lumacaftor for improved brain blood flow in heart failure
This trial tests if lumacaftor, a medication used in cystic fibrosis, can improve blood flow to the brain in people with stable heart failure. It might help if you have heart failure with reduced pumping function and low brain blood flow.
Toronto, OntarioAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 949 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.