Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06374277Recruiting
Pharmacy Coaching to Help After Hospital Stay
This study tests a program where a pharmacist helps you manage your medications after you leave the hospital. It is for people with long-term health conditions who want to stay on track with their medicines.
Knoxville, TennesseeAges 18 years+ - NCT01258231Recruiting
Genetic test to predict risks after heart surgery
This study looks for genetic (DNA) clues that may help predict side effects or complications after heart surgery. If you join, your genome information may be used to understand who is at higher risk and why.
Boston, MassachusettsAges 20–90 - NCT06645691RecruitingPhase 2
Heart and metabolic imaging study using a special MRI scan
This study tests a new MRI method that uses a safe, natural substance (pyruvate) to take detailed pictures of the heart and metabolism. It may help doctors better understand heart disease, diabetes, and related conditions.
SingaporeAges 21–99 - NCT07518862Recruiting
Using heart rate to guide oxygen therapy settings
This study uses a simple, non-invasive test (heart rate monitoring) to help doctors adjust the flow of oxygen therapy through a nasal cannula. It may help improve how well this breathing support works for you.
Toronto, OntarioAges 18 years+ - NCT07450846Recruiting
Heart-lung interaction in severe breathing problems
This study looks at how the heart and lungs interact in patients with acute respiratory distress syndrome (a severe lung condition) who are on a breathing machine. Researchers will use ultrasound to check heart function at different times during treatment.
Le Kremlin-BicêtreAges 18 years+ - NCT07444398RecruitingPhase 1
Vericiguat for worsening heart failure
This trial tests if adding vericiguat to standard heart failure medicines helps people hospitalized with worsening heart failure. It's for those with a weak heart pump and high NT-proBNP levels.
Rawalpindi, Punjab ProvinceAges 25–65 - NCT06775028Recruiting
Integrated care for older adults with atrial fibrillation
This trial is testing a new approach to care for older adults with atrial fibrillation (an irregular heartbeat) who also have other health conditions. It aims to see if a more integrated, team-based care plan helps improve their overall health and quality of life.
HaskovoAges 65 years+ - NCT07096973Recruiting
Heart rehab recovery study in Davos
This study looks at how people recover during heart rehabilitation at a clinic in Davos. By tracking your progress, researchers hope to learn what helps people get better.
Davos, Kanton GraubündenAges 18 years+ - NCT05465031RecruitingPhase 4
Testing heart-protection medicine during breast cancer treatment
This trial tests sacubitril/valsartan to help prevent heart weakness (cardiotoxicity) caused by breast cancer treatments like anthracyclines and/or anti-HER2 drugs. If you qualify, you may be offered this heart-protection medicine while your cancer is treated.
Opole, Opole VoivodeshipAges 18 years+ - NCT04666454RecruitingPhase 4
Medication trial for broken heart (Takotsubo) syndrome
This trial tests an optimized medication approach for people diagnosed with Takotsubo (“broken heart”) syndrome. It may help clinicians find a safer and more effective treatment plan after this heart condition.
AarhusAges 18 years+ - NCT07830758RecruitingPhase 1
Resmetirom for fatty liver disease with heart failure
This trial tests a drug called resmetirom for people who have both a type of fatty liver disease (MASH) and a type of heart failure (HFpEF). It aims to see if the drug can help both conditions. You may be able to join if you have both conditions and meet certain health criteria.
Peoria, ArizonaAges 18 years+ - NCT07835828Recruiting
Optimised heart and kidney protection for chronic kidney disease and heart disease
This study tests a new approach to protect the heart and kidneys in people with both chronic kidney disease and heart or blood vessel problems. By optimising treatment, researchers hope to reduce the risk of further kidney or heart damage.
SvendborgAges 18 years+ - NCT03398369Recruiting
Imaging study to guide heart failure device treatment
This study uses advanced heart imaging to better understand heart function in people who may benefit from a cardiac resynchronization therapy (CRT) device. It aims to find ways to improve how doctors choose treatment and tailor care.
Charlottesville, VirginiaAges 20–90 - NCT04162444Recruiting
Aortic valve reconstruction study for children
This trial studies a surgery approach to help fix a narrowed or leaking aortic valve in children. It aims to see how well the reconstructed valve works and how it affects the child’s heart function over time.
MoscowAges 4 weeks–12 years - NCT04377854Recruiting
Checking whether BNP predicts outcomes in advanced heart failure
This study looks at whether a blood test called BNP can help predict what happens over time in people being evaluated for advanced heart failure treatment. It may help doctors better plan care and follow-up for patients long-term.
Copenhagen, DKAges 18 years+ - NCT04191681RecruitingPhase 4
Testing ARNI in people with implanted LVAD devices
This trial studies whether a heart medicine called ARNI (sacubitril-valsartan) is safe and works well for people who have a durable LVAD and moderate-to-severe heart pumping weakness. It may help improve symptoms and outcomes, while carefully checking side effects in this higher-risk group.
Cleveland, OhioAges 18 years+ - NCT03269630Recruiting
Pulmonary hypertension biobank for heart-lung blood samples
This study collects and stores health information and possibly blood samples from people being evaluated for pulmonary hypertension or related autoimmune conditions. It helps researchers learn more about these illnesses and may support future studies.
New Orleans, LouisianaAges 18 years+ - NCT05028686Recruiting
Using blood tests and AI to predict heart failure readmissions
This study looks at hospital and emergency patients with heart failure and uses “omics” (advanced lab data from the body) plus statistics and artificial intelligence to predict who is likely to return to the hospital soon. If it works, it could help doctors better plan follow-up care to reduce repeat hospital visits.
Toronto, OntarioAges 18–105 - NCT02818517Recruiting
Cardio-oncology checkup to understand heart side effects
This study looks at how cancer treatments may affect the heart (“cardiotoxicity”) and how patients are monitored and managed. You might benefit by getting close heart-related follow-up as part of the care plan.
Tel AvivAges 18 years+ - NCT05271214Recruiting
Testing conservative care for people with failing heart pumps
This trial is studying a non-surgical (conservative) treatment approach for people being considered for a left ventricular assist device (LVAD). It may help some patients who are too sick or unable to tolerate standard heart failure medicines, but it will only match people with specific heart function and health-test results.
Tel AvivAges 18–80 - NCT04602338Recruiting
Imaging tests to better diagnose heart failure with preserved function
This trial uses several types of heart imaging to diagnose heart failure where squeezing function is still fairly normal. It may help doctors sort out what’s causing your symptoms and guide better care by comparing imaging findings across many patients.
Beijing, Beijing MunicipalityAges Any age - NCT05106270Recruiting
Atrial pressure changes around a heart procedure for atrial fibrillation
This trial studies how changing pressure in the heart’s upper chamber before and after a combined heart procedure affects outcomes in people with atrial fibrillation. It may help guide safer, more effective care for patients who need left atrial appendage closure (a way to reduce stroke risk).
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04603404Recruiting
Imaging tests to find and predict HFpEF risk
This study uses different heart imaging tests to help screen for HFpEF (heart failure with preserved pumping strength), make the diagnosis, and estimate your future risk. You may benefit by getting a clearer diagnosis and a better risk picture based on the scans.
Beijing, Beijing MunicipalityAges Any age - NCT04709900Recruiting
Tests for stable chest pain using heart scans and pressure measurements
This trial studies how well different heart tests (imaging the blood flow and measuring blood pressure in the heart) work for people with stable chest pain. It may help guide safer, more accurate evaluation when you are not having a heart attack.
CopenhagenAges Any age
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 949 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.