Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04931550Recruiting
Pacemaker site study to see which placement is best
This study looks at whether placing a pacemaker in different locations affects how patients do afterward. If you recently had a pacemaker implanted and can follow study instructions, you may be able to help researchers compare outcomes.
Hangzhou, ZhejiangAges 18–100 - NCT05532631Recruiting
Compare stent procedure versus bypass surgery for weak heart
This study compares two ways to improve blood flow to the heart—using stents through a catheter or bypass surgery—in people with heart muscle weakness and blockages in more than one coronary artery. It may help identify which approach leads to better outcomes over at least two years.
Créteil, Val De MarneAges 18 years+ - NCT05732051RecruitingPhase 2
Nicotinamide riboside to protect the heart during breast cancer chemo
This trial tests whether nicotinamide riboside can help prevent heart problems caused by a common breast-cancer chemotherapy (anthracyclines). If you’re eligible, you’ll be followed to see how your heart is doing during treatment.
Lørenskog, AkershusAges 18 years+ - NCT05718128RecruitingPhase 4
Study of taking heart muscle samples from the inside
This trial studies patients who need an endocardial myocardial biopsy, meaning a small heart muscle sample taken from inside the heart. It’s meant for people with heart problems whose cause is not clearly known and may help doctors learn more about what’s going on.
Hangzhou, ZhejiangAges 18–80 - NCT05179616Recruiting
Study of TriClip treatment for severe leaky tricuspid valve
This study follows adults with a severely leaky tricuspid heart valve who still have symptoms despite medication. It looks at outcomes after a procedure called TriClip, which helps reduce valve leakage.
PforzheimAges 18 years+ - NCT06081205Recruiting
Heart disease patients in intensive care study
This trial observes patients admitted to the cardiac intensive care unit with acute heart or blood vessel problems. It aims to learn more about their conditions and treatments.
Ioannina, EpirusAges Any age - NCT06115096Recruiting
Heart pump blood flow study
This study looks at how blood flows inside your heart while you have a HeartMate 3 heart pump. It aims to understand your heart’s pumping function and may help doctors improve care for people with heart pumps.
Linköping, Östergötland CountyAges 18 years+ - NCT06142474RecruitingPhase 3
SGLT2 inhibitors for heart failure patients during ventilator weaning
This trial tests a heart failure medication (SGLT2 inhibitor) to help people with heart failure who are on a breathing machine (ventilator) get better and come off the machine faster. It is for patients with a specific type of heart failure where the heart pumps weakly (EF ≤ 40%).
TaipeiAges 20 years+ - NCT06125925Recruiting
Ablation for AFib in patients with heart failure and preserved ejection fraction
This study tests whether a catheter ablation procedure can help people with atrial fibrillation and a kind of heart failure where the heart pumps normally but doesn't relax properly (HFpEF). It looks at whether the procedure can improve symptoms and heart function.
NanjingAges 18–80 - NCT06078436Recruiting
Early carvedilol for heart failure shock
This trial tests whether starting the heart failure medication carvedilol early, along with standard monitoring, can help people in cardiogenic shock (when the heart can't pump enough blood) due to a weak heart muscle. It aims to see if earlier treatment improves outcomes.
SeoulAges 19 years+ - NCT07856472Recruiting
AI heart test study for heart disease diagnosis
This study uses artificial intelligence to analyze heart tests (ECGs) to help diagnose and predict outcomes for people with heart disease. It may lead to better and faster detection of heart conditions.
Incheon, IncheonAges 18 years+ - NCT07866859Recruiting
Leg ultrasound to predict heart pressure
This study checks if a leg ultrasound can help doctors estimate the pressure in your heart's main pumping chamber before a heart procedure. If it works, it could give useful information without extra tests.
Chon BuriAges 18–100 - NCT05694572Recruiting
Device follow-up for certain MicroPort CRM heart implants
This study checks how well specific MicroPort CRM heart devices and leads work in real life over time. If you already have one of these FDA/market-approved implants and can be followed yearly, the study helps the company monitor safety and performance.
LisbonAges 18–90 - NCT07858799Recruiting
Study of a new device for heart failure with reduced pumping ability
This trial tests a new device that creates a small shunt (passage) in the heart to help relieve pressure and improve symptoms in people with heart failure and a weak heart pump. The goal is to see if the device is safe and helpful for patients like you.
Cologne, GermanyAges 18 years+ - NCT03523416Recruiting
Shunt device for heart failure with reduced pumping function
This trial studies a small device placed in the heart to create a passage that may help relieve pressure and improve symptoms in people with heart failure and a weak pumping function. It aims to see if the device is safe and helpful for daily life.
La Jolla, CaliforniaAges 18 years+ - NCT06055504Recruiting
Personalized defibrillator plan for non-ischemic heart failure (SPANISH-1)
This trial is testing a personalized approach to deciding who gets an implantable defibrillator (ICD) for people with heart failure due to dilated cardiomyopathy (not from blocked arteries). It aims to see if MRI scans and other factors can better match the device to those who need it most.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT06090591Recruiting
Heart condition research registry at Dubrava Hospital
This study is a registry that will collect information from people with certain heart conditions (like having a pacemaker, a blood clot, a heart attack, or a valve replacement procedure called TAVI). The goal is to learn more about these conditions and how they are treated.
ZagrebAges 18 years+ - NCT04905160Recruiting
Care planning after hospital stays to reduce readmissions
This study tests a care-coordination plan to see if it helps people leave the hospital and prevents them from needing to come back soon. It focuses on certain heart-related hospital diagnoses and, for some parts, also includes people with recent COVID-19.
Phoenix, ArizonaAges 18 years+ - NCT06356727Recruiting
Blood vessel health test for heart recovery
This study checks if tiny blood vessel problems in the heart affect how well the heart muscle recovers after being weak. It uses special imaging during a routine heart catheterization to look at these small vessels.
FerraraAges 18–85 - NCT01999140Recruiting
ICD and CRT-D device registry for patients worldwide
This trial is a real-world registry that collects information from people who receive an implantable heart defibrillator or related device. It helps doctors understand how these devices are used and how patients do over time.
Washington D.C., District of ColumbiaAges Any age - NCT06208007Recruiting
Predicting heart failure with stiff arteries
This study looks at whether stiffer arteries can help predict a type of heart failure where the heart doesn't relax properly (HFpEF). It's for people who have risk factors like high blood pressure, diabetes, or being older, and who may have early signs of heart trouble.
Göttingen, Lower SaxonyAges 18 years+ - NCT07852221Recruiting
Pace and ablate for atrial fibrillation
This study looks at how well a treatment called 'pace and ablate' works for people with atrial fibrillation. It involves using a pacemaker or similar device to control the heart rate, and it aims to see who benefits most and how they do over time.
ZabrzeAges 18 years+ - NCT05851053Recruiting
Study of heart function years after breast cancer treatment
This study checks how well your heart works long after breast cancer treatment. If you joined the earlier de BLOC-I study, you may be invited for follow-up to understand long-term heart effects.
GroningenAges Any age - NCT06459934Recruiting
Heart and cardiovascular disease study
This study looks at the health outcomes of people with common heart conditions like coronary artery disease, high blood pressure, heart failure, or cardiomyopathy. It may help researchers understand how these conditions progress and how to better manage them.
Ürümqi, XinjiangAges 18–80
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 949 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.