Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07825363Recruiting
Early warning system for heart failure or heart attack patients
This study tests a sensor that monitors oxygen levels in body tissues to help doctors spot when your heart is not pumping enough blood early. The goal is to catch problems sooner so you can get faster treatment.
Weston, FloridaAges 18 years+ - NCT07809516Recruiting
Pedal pump for leg swelling
This trial tests a device called a 'pedal pump' that helps move fluid out of your legs to reduce swelling. It may help if you have fluid buildup from conditions like heart failure or kidney disease.
Tulsa, OklahomaAges 18 years+ - NCT05593679Recruiting
Registry study for heart PYP scans in possible ATTR amyloidosis
This study collects information from adults who have been diagnosed with, or are being checked for, ATTR amyloidosis (a condition where abnormal protein builds up in the body) using a heart PYP scan. Your participation may help doctors better understand how these scans relate to diagnosis and follow-up over time.
New Taipei CityAges 20 years+ - NCT07791407Recruiting
Heart imaging to guide defibrillator placement in heart failure
This study uses an MRI scan of the heart to better identify which people with heart failure need a defibrillator along with a special pacemaker (cardiac resynchronization therapy). The scan may help doctors decide if the device could improve your heart's pumping and reduce risks.
Madurai, Tamil NaduAges 18 years+ - NCT01390675Recruiting
Registry for heart valve replacement anesthesia during TAVR
This study tracks patients who get a transcatheter aortic valve implantation (TAVR), a procedure to replace a narrowed heart valve without open-heart surgery. It looks at the type of anesthesia used during the procedure and records outcomes to learn what works best for patients.
Munich, BavariaAges 18 years+ - NCT06311149Recruiting
Study of LATITUDE heart device monitoring
This trial looks at how well the LATITUDE monitoring system works for people with heart devices. It checks if remote monitoring helps doctors track how your device is doing, so they can spot problems early.
FerraraAges Any age - NCT07760363Recruiting
Foot exercise device for leg swelling
This study tests if using a foot pedal device while lying down can help reduce leg swelling in the hospital. It aims to see if this simple exercise can improve comfort and outcomes for people with fluid buildup.
Tulsa, OklahomaAges 18 years+ - NCT06584266Recruiting
Cardiac imaging registry for atrial fibrillation
This study collects data from heart imaging tests (TEE) in people with atrial fibrillation or atrial flutter. It aims to better understand how these imaging results relate to treatment decisions and outcomes.
BrnoAges 18 years+ - NCT07750873RecruitingPhase 2
Study of an investigational medicine for heart failure with reduced pumping function
This trial tests an investigational medicine called CRD-4730 (taken as a pill) to see if it can improve heart function and symptoms in people with heart failure and a reduced pumping ability. It may help you feel better and slow the progression of your condition.
Pasadena, CaliforniaAges 18–85 - NCT07749183Recruiting
Light-based detection of atrial fibrillation in heart failure
This study tests a new device that uses light to detect irregular heartbeats (atrial fibrillation) in people with heart failure. If you join, you'll wear a small sensor that may help catch early signs of this condition.
BratislavaAges 18 years+ - NCT05761067Recruiting
Trial for advanced heart weakness with low pumping ability
This study looks at treatment options for adults with significantly reduced heart pumping strength and extensive coronary artery disease. It may help people who are at higher risk due to widespread blocked heart arteries, but eligibility depends on recent heart events and bleeding risk.
GothenburgAges 18 years+ - NCT07733960Recruiting
Pacing system study for heart pacing therapy
This trial tests a new pacing system designed to improve how pacemakers work. It may help people who need a pacemaker with left bundle branch area pacing.
Madurai, Tamil NaduAges 18 years+ - NCT07730268Enrolling by invitation
Vivio at-home study for heart failure monitoring
This study tests a home monitoring device (Vivio) for people who already have a CardioMEMS implant to check if the new device can track your heart health easily at home.
Long Beach, CaliforniaAges 21 years+ - NCT07721649Recruiting
Flu shot during hospital stay for heart patients
This study checks if giving a flu shot to heart patients while they are in the hospital helps prevent heart problems later. It tests whether the flu shot can reduce the risk of further heart events.
CologneAges 18 years+ - NCT04344912Recruiting
Study of COVID-19 effects on heart emergency care
This study looks at how the COVID-19 outbreak affected care for people admitted to the cardiac intensive care unit. It may help hospitals improve how they plan and respond during major outbreaks.
ParisAges 18 years+ - NCT07709208Recruiting
Mitral valve repair for leak that worsens with exercise
This trial tests a procedure to fix a leaky mitral valve that only becomes severe during exercise. It may help people with symptoms like shortness of breath or fatigue who haven't responded to standard heart medications.
DüsseldorfAges 18 years+ - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT07701369Recruiting
AI-assisted heart ultrasound for older adults with heart failure
This trial tests whether artificial intelligence can help interpret heart ultrasounds in older patients with acute heart failure. It aims to make echocardiograms more accurate and easier to obtain in geriatric care.
ParisAges 75 years+ - NCT05327062Recruiting
Noninvasive mapping to guide a heart resynchronization device
This trial tests a noninvasive way to map your heart’s wiring and veins to help guide placement of a heart resynchronization therapy (CRT) device. If you have certain abnormal heart rhythm and weak heart pumping, it may help doctors place the therapy more accurately and safely.
Chicago, IllinoisAges 18 years+ - NCT07666698RecruitingPhase 1/Phase 2
Metformin to improve heart function after LVAD implant
This trial tests if metformin, a medicine commonly used for diabetes, can help improve heart function in people who have a mechanical heart pump (LVAD). You may be able to join if you are between 18 and 75, have a continuous-flow LVAD, and have a condition called insulin resistance (where your body doesn't use insulin well) but your blood sugar levels are well-controlled.
Nanjing, JiangsuAges 18–75 - NCT07664189Enrolling by invitation
Left bundle pacing plus CRT vs. LBBP alone
This trial tests a new pacing approach that combines a left bundle branch pacemaker with standard cardiac resynchronization therapy (CRT) for people with heart failure. It aims to improve the heart's pumping efficiency compared to using the left bundle branch pacemaker alone.
Medellín, AntioquiaAges 18 years+ - NCT07656454RecruitingPhase 1
Comparing two ways to give CDR132L in healthy volunteers
This study measures how well the drug CDR132L enters the blood when injected under the skin, compared to injection into a vein. It is done in healthy volunteers to find the best way to give the drug.
BerlinAges 18–55 - NCT07643818Enrolling by invitationPhase 2
Intravenous iron for heart failure patients with low iron
This study tests whether giving intravenous iron improves symptoms, quality of life, and exercise ability in people with heart failure and low iron levels. Participants will receive iron infusions and be monitored over time to see if their condition improves.
Saint HelierAges 18 years+ - NCT07643610Recruiting
Heart Failure Crisis Registry Study
This registry collects information from patients admitted to the hospital with cardiogenic shock—a serious condition where the heart cannot pump enough blood to the body. Doctors will gather data to better understand what happens to these patients and how to improve their care.
Basel, Canton of Basel-CityAges 18 years+
Hear when a new Heart failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 949 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.