Clinical trials
Heart Valve Diseases clinical trials
Below are recruiting heart valve diseases clinical trials, each written for real people, not researchers. We’re tracking 227 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04073420Recruiting
Cardiac surgery registry to track Medtronic device outcomes
This registry collects real-world information from people who have had—or plan to have—an eligible Medtronic cardiac surgery device. It aims to better understand how these treatments do over time and help guide future care.
Marietta, GeorgiaAges Any age - NCT03376165Recruiting
Study heart rhythm problems after heart surgery
This trial looks at heart rhythm issues (especially atrial fibrillation) that can happen after certain heart procedures. It may help doctors better predict, prevent, or manage these rhythm problems after surgery.
LilleAges 18 years+ - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT06634121Recruiting
Comparing MitraClip and PASCAL for mitral valve repair
This trial compares two devices (MitraClip and PASCAL) for repairing a leaky mitral valve (mitral regurgitation). The goal is to see which device works better in a wide range of patients who need this type of repair.
Munich, BavariaAges 18 years+ - NCT06688448Recruiting
New biologic aortic valve replacement study
This study is testing a new generation of biologic (tissue) replacement valves for the aortic valve in adults aged 18 to 65. It aims to see how well these newer devices work compared to standard options.
São Paulo, São PauloAges 18–65 - NCT07176507Recruiting
Study of multiple and mixed heart valve disease
This study looks at people who have two or more heart valve problems that are moderate to severe. It aims to learn more about this condition and how to best manage it.
LilleAges 18 years+ - NCT07065500Recruiting
Study of new metabolites for heart valve disease
This study looks at certain byproducts in your body (metabolites) that may be linked to heart valve disease. The goal is to understand how they work, which could lead to better treatments.
Guangzhou, GuangdongAges 18 years+ - NCT07042529Recruiting
Optimizing valve placement during TAVI
This trial is testing a better way to position a new heart valve during a TAVI procedure. The goal is to help the valve work as well as possible for people with severe aortic stenosis.
AalstAges 18 years+ - NCT04454177Recruiting
Smartwatch help to discharge earlier after valve replacement
This study tests whether using a smartwatch can safely help people leave the hospital earlier after a transcatheter aortic valve replacement (TAVR). It checks comfort, safety, and follow-up at home.
Hangzhou, ZhejiangAges 18 years+ - NCT07466745Recruiting
New Pulmonary Valve Study for Kids Needing Replacement
This study tests a new type of replacement valve for children who need a new pulmonary valve (the valve between the heart and lungs). Researchers want to see if the valve works safely and well in real-world use.
Los Angeles, CaliforniaAges 1.5 years–16 years - NCT06937983Recruiting
Mapping to guide heart rhythm treatment
This study tests a new way of mapping damaged heart muscle to improve the precision of a procedure called catheter ablation, which treats dangerously fast heart rhythms. It may help people with heart disease who need this procedure.
Coventry, West MidlandsAges 18 years+ - NCT06789211Recruiting
Outcomes in moderate mixed aortic valve disease
This study looks at people with a combination of moderate aortic stenosis and regurgitation, comparing them to those with severe aortic valve problems. It aims to understand outcomes and help guide treatment decisions.
Leiden, South HollandAges 18 years+ - NCT07258290Recruiting
Freesolve Magnesium Scaffold for Heart Artery Blockages
This trial tests a new dissolvable magnesium scaffold to treat blockages in heart arteries. It is designed for people with stable heart pain or certain recent heart attacks, and it aims to open blocked arteries and then slowly dissolve over time.
Washington D.C., District of ColumbiaAges 18–80 - NCT07213531Recruiting
AI guidance for heart valve treatments
This trial uses artificial intelligence to improve outcomes for patients getting minimally invasive heart valve procedures. It looks at CT scans and ultrasound images to help doctors plan and perform treatments for the aortic, mitral, and tricuspid valves.
New York, New YorkAges 18 years+ - NCT05386173Recruiting
Tests fetal aortic valve balloon surgery for severe narrowing
This trial studies whether doing a procedure before birth to open a baby’s aortic valve improves outcomes. It compares this approach in a specific group of pregnancies with severe heart flow problems seen on ultrasound.
San Francisco, CaliforniaAges 5 months–7 months - NCT07407816Recruiting
Supira heart support device for high-risk artery stenting
This trial tests a new device (the Supira system) that helps support your heart's pumping function during and after a high-risk procedure to open blocked coronary arteries. It is for people with heart failure and complex blockages who may need extra circulatory support.
Tbilisi, K'alak'i T'bilisiAges 18–90 - NCT05632432Recruiting
Heart tissue grafts to help the heart after surgery
This trial tests whether transplanting tiny heart “micrografts” from the left heart chamber area can improve heart function after cardiac surgery. It is meant for people with weakened heart pumping and heart failure symptoms despite medicine.
Helsinki, UusimaaAges 18–75 - NCT02219984Recruiting
Survey of adults taking blood thinners in a patient registry
This study builds a registry by asking adults who take blood thinners (anticoagulants) about their experiences. It may help improve care by learning how these medicines are used in real life.
Bologna, BOAges 18 years+ - NCT05139589Recruiting
Collecting data from adults with heart valve infection
This study collects information about adults who are treated in Amsterdam UMC for infective endocarditis (a serious infection of the heart valves). The goal is to better understand this condition—especially for people undergoing heart valve surgery—by comparing them to similar surgery patients who do not have an infection.
Amsterdam, North HollandAges 18 years+ - NCT07744009Recruiting
Awake breathing support for heart valve surgery
This trial tests a new anesthesia method that lets you breathe on your own during heart valve surgery, instead of using a breathing tube. It aims to see if this approach is safer and helps you recover faster than standard anesthesia.
Guangzhou, GuangdongAges 18 years+ - NCT07588230Recruiting
Nerve Block for Minimally Invasive Heart Valve Surgery Pain
This study tests a targeted nerve block (pain-numbing injection) to help manage pain after minimally invasive heart valve surgery. Researchers want to see if this technique reduces pain and the need for opioid medications during recovery.
Diyarbakır, Outside of the USAges 18–75 - NCT07568795Recruiting
Testing a portable electronic stethoscope for heart valve disease
This study validates a new portable electronic stethoscope that can help detect heart valve disease. If you've had an echocardiogram (heart ultrasound) recently, researchers want to test whether this device accurately identifies valve problems.
Hong Kong, Pok Fu Lam Rd.Ages 18 years+ - NCT07449130Recruiting
AI screening for valve disease using chest CT scans
This study uses a computer AI to look at routine chest CT scans and find people who might have valvular heart disease (problems with the heart's valves). It aims to see if AI can help catch these issues early, so you can get the right care sooner.
Wuhan, HubeiAges 18 years+ - NCT07390903Recruiting
Heart function test for difficult bypass weaning
This trial studies whether a heart ultrasound test called GLS can help predict complications when patients are taken off the heart-lung machine after heart surgery. It aims to improve management for better outcomes.
RomeAges 18 years+
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Common questions
- Are there clinical trials for heart valve diseases?
- Yes. Clin2 currently lists 227 recruiting heart valve diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart valve diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart valve diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.