Clinical trials
High Grade Glioma (III or IV) clinical trials
Below are recruiting high grade glioma (iii or iv) clinical trials, each written for real people, not researchers. We’re tracking 1,259 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04180930Recruiting
Comparing two PTSD screening tests
This study compares two different questionnaires doctors use to assess PTSD (post-traumatic stress disorder) symptoms. If you’ve had a traumatic event and currently have PTSD symptoms, it may help improve how PTSD is identified in active-duty service members and veterans.
Honolulu, HawaiiAges 18 years+ - NCT06788366Recruiting
AI tool to predict outcomes in metastatic lung cancer
This trial is testing whether artificial intelligence can help predict how well people with advanced non-small cell lung cancer (NSCLC) respond to immunotherapy or chemo-immunotherapy. If you have stage IV NSCLC and have started this treatment, your data may help build a better prediction tool.
MilanAges 18 years+ - NCT07471555Enrolling by invitation
Vascular access and intraosseous study for nursing students
This trial tests a teaching method for inserting a special needle into bone (intraosseous access) and regular IV lines. It is only for 4th year nursing students.
Valencia, ValenciaAges 18 years+ - NCT06793787Recruiting
AI and advanced imaging to guide treatment of borderline heart blockages
This study uses advanced CT scans and a special camera (OCT) to look at borderline blockages in heart arteries more closely. It aims to see if artificial intelligence can help decide which blockages need a stent and which can be treated with medicine alone.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07462650RecruitingPhase 1/Phase 2
CAR-NK cell therapy for advanced colorectal cancer
This trial tests a new treatment using modified natural killer cells (CAR-NK) that target two specific proteins found on your cancer cells. It is for people with advanced colorectal cancer who have tried standard treatments without success.
Shenzhen, GuangdongAges 18–75 - NCT07457060RecruitingPhase 4
Polio vaccine study for 2-month-old infants
This study tests giving babies two different types of polio vaccines in a specific order to see which is safer and more effective. If your baby is about 2 months old and hasn't had any polio vaccine yet, they may be able to join.
Kawit, CaviteAges 2 months–3 months - NCT07459673RecruitingPhase 2
HER2-positive breast cancer trial using ctDNA to guide treatment
This trial tests a personalized treatment plan for HER2-positive breast cancer that has spread. It uses a blood test to track cancer DNA and adjust therapy, including treatments that may help prevent cancer from reaching the brain. The goal is to achieve long-term remission.
Basking Ridge, New JerseyAges 18 years+ - NCT07460362RecruitingPhase 2
Glofitamab and lenalidomide for high-risk mantle cell lymphoma
This trial tests a combination of two drugs, glofitamab and lenalidomide, for people with mantle cell lymphoma that has come back or not responded to treatment. It's for those with high-risk features, like a fast-growing lymphoma or resistance to previous therapies.
Beijing, Beijing MunicipalityAges 18–80 - NCT07455903RecruitingPhase 2
Hormone therapy before surgery for high-risk prostate cancer
This trial tests whether giving hormone therapy (androgen deprivation therapy) before surgery can improve outcomes for men with high-risk prostate cancer. You will receive a special PSMA PET/CT scan to see how the cancer responds.
Miami, FloridaAges 18 years+ - NCT06101511Recruiting
Breathing tube pressure for safer abdominal surgery
This trial is testing if using less air pressure from the breathing machine during abdominal surgery can help prevent lung complications. If you are at higher risk for breathing problems after surgery, this study may help find a safer way to manage your breathing during the operation.
Amsterdam, NoordhollandAges 18–100 - NCT07447908Recruiting
Understanding worsening heart failure after leaving the hospital
This study monitors heart failure patients after a hospital stay or urgent clinic visit to better understand the signs of worsening heart failure. It may help researchers find ways to predict and prevent future exacerbations.
Newmarket, OntarioAges 18 years+ - NCT06805812Recruiting
Predicting outcomes of CDK4/6 inhibitors plus hormone therapy for advanced breast cancer
This study looks at how well a type of targeted therapy (called CDK4/6 inhibitors) combined with hormone therapy works as the first treatment for advanced breast cancer that is hormone receptor-positive and HER2-negative. Researchers want to find patterns that could help predict which patients benefit most.
AvianoAges 18 years+ - NCT07440290RecruitingPhase 2/Phase 3
Dabrafenib and trametinib for BRAF V600 cancers
This trial tests two targeted drugs (dabrafenib and trametinib) for patients whose cancer has a specific change in the BRAF gene called V600. These drugs work together to block signals that help the cancer grow. The trial is for children, teenagers, and adults with many types of cancer, except for a few common ones that already have approved treatments.
BelfastAges 1 year+ - NCT07443254RecruitingPhase 1/Phase 2
IR-led deep sedation study for image-guided procedures
This study tests if a radiologist can safely give deep sedation medicine (ketamine) for certain procedures instead of general anesthesia. It might help you avoid general anesthesia while still being comfortable.
Charleston, West VirginiaAges 18 years+ - NCT07438002Recruiting
Exercise for kidney disease patients on dialysis or in treatment
This trial studies whether high-intensity physical exercise helps people with chronic kidney disease, including those on dialysis. It aims to improve health and physical function.
Peschiera del Garda, VeronaAges 18 years+ - NCT07443410Recruiting
Probiotics for gum disease treatment
This trial tests whether taking pre- and probiotics alongside non-surgical gum treatment improves healing and reduces harmful bacteria. It may help people with advanced gum disease (stage III or IV periodontitis).
Heidelberg, Baden-WurttembergAges 18 years+ - NCT05204888Recruiting
Home breathing device study for COPD patients after recent flare-up
This study tests whether a home high-flow nasal breathing device (myAirvo 3) helps people with COPD who recently needed hospital care for a flare-up. You would use the device at home and track symptoms, oxygen levels, and heart rate daily to see how well it works.
Birmingham, AlabamaAges 30 years+ - NCT07429240RecruitingPhase 1/Phase 2
Gene editing trial for Duchenne muscular dystrophy (ages 2-7)
This trial tests a new gene editing treatment called PBGENE-DMD for boys with Duchenne muscular dystrophy (DMD) whose genetic mutation falls within a specific range of the dystrophin gene (exons 45-55). The goal is to see if it is safe and can help improve muscle function.
Little Rock, ArkansasAges 2–7 - NCT07430345RecruitingPhase 1/Phase 2
Buprenorphine for pain in older adults with broken bones
This trial tests a low-dose pain medicine called buprenorphine for people 65 and older who come to the emergency room with a broken bone. It aims to find a safe way to manage pain in older adults.
Camden, New JerseyAges 65 years+ - NCT07428993RecruitingPhase 2
CAR T-Cell Therapy for High-Risk Osteosarcoma
This trial tests a new type of cell therapy called B7-H3 CAR T cells for children and young adults with high-risk osteosarcoma that hasn't spread or worsened after standard chemotherapy. The treatment uses your own immune cells that are modified to attack a protein (B7-H3) found on cancer cells.
Memphis, TennesseeAges Up to 21 years - NCT06814899Recruiting
Fosfomycin for bacterial infections in hospitalized adults
This study looks at how well the antibiotic fosfomycin works for bacterial infections in patients who received it in the hospital. It may help doctors understand the best ways to use this medicine.
Lecco, LeccoAges 18 years+ - NCT07419828RecruitingPhase 3
Study of HRS-1780 for chronic kidney disease
This trial tests an investigational drug called HRS-1780 in people with chronic kidney disease. It aims to see if the drug can help slow kidney decline and is safe to use.
Nanjing, JiangsuAges 18–80 - NCT07423650RecruitingPhase 4
Continuous Nefopam infusion after pancreas surgery
This trial tests if giving a steady dose of a painkiller called nefopam through an IV can help manage pain after a Whipple procedure (pancreatoduodenectomy). It aims to see if this approach reduces the need for other pain medications and improves recovery.
Cluj-Napoca, ClujAges 18–80 - NCT07418125Recruiting
Study of tumor cell clusters in high-risk early breast cancer
This trial looks at whether clusters of tumor cells in the blood can give more information about high-risk early breast cancer. It is for people with certain types of breast cancer who are about to start treatment before surgery (neoadjuvant therapy).
LjubljanaAges 18 years+
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Common questions
- Are there clinical trials for high grade glioma (iii or iv)?
- Yes. Clin2 currently lists 1,259 recruiting high grade glioma (iii or iv) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high grade glioma (iii or iv) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high grade glioma (iii or iv) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.