Clinical trials
Hormone Therapy clinical trials
Below are recruiting hormone therapy clinical trials, each written for real people, not researchers. We’re tracking 130 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06291675Recruiting
Hormone therapy's effect on heart and organ fat
This study uses MRI scans to see how gender-affirming hormone therapy affects heart muscle, heart function, and fat in the heart, liver, and pancreas. It may help us understand long-term health effects of hormone therapy.
Vienna, State of ViennaAges 18 years+ - NCT07594002Recruiting
Acupuncture for hot flashes in prostate cancer patients
This study tests whether real acupuncture works better than fake acupuncture for reducing hot flashes (sudden episodes of intense heat and sweating) in men with prostate cancer who are on hormone therapy. If acupuncture helps, it could offer relief without more medications.
Lexington, KentuckyAges 18–99 - NCT06530459RecruitingPhase 2/Phase 3
The MUSE Study for Menopausal Joint Pain
This study tests whether a treatment can help women with joint pain and stiffness that started or worsened during menopause. It focuses on women who are within 5 years of menopause and have pain in multiple joints.
SingaporeAges 30–59 - NCT06832774RecruitingPhase 2
Hormone therapy plus local treatment for advanced prostate cancer
This study tests adding a targeted local treatment (like radiation or surgery) to standard hormone therapy for men with advanced prostate cancer that still shows up on a special scan. The goal is to see if this combination helps control the cancer better.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06510647Recruiting
Risk factors for hormonal therapy failure in endometriosis
This study looks at why some people with endometriosis stop responding to hormonal treatments. It aims to find risk factors for treatment failure, which could help doctors choose better therapies in the future.
Monserrato, CagliariAges 18–50 - NCT07675213Recruiting
Uterine muscle movements and pregnancy after frozen embryo transfer
This trial explores how natural uterine contractions affect pregnancy success in women using hormone therapy for frozen embryo transfer. It may help doctors understand if uterine activity influences implantation.
Ho Chi Minh CityAges 18–42 - NCT07278323RecruitingPhase 4
Hormone therapy for frozen shoulder
This study tests if hormone replacement therapy can help treat frozen shoulder. It is designed for people with frozen shoulder in just one shoulder who are not currently using hormones and have no history of hormone-sensitive cancer.
San Francisco, CaliforniaAges 40 years+ - NCT06306612Recruiting
Surgery plus hormone therapy for advanced prostate cancer
This trial tests whether removing the prostate (surgery) plus standard hormone therapy and chemotherapy can help men whose prostate cancer has spread to many places in the body. It is for men who have not yet had treatment for their cancer.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT07391774RecruitingPhase 3
Hormone therapy with or without chemo for early breast cancer
This trial tests whether skipping chemotherapy and using only hormone therapy with a drug called ribociclib works as well as chemotherapy followed by hormone therapy with ribociclib for certain early breast cancers that have a low risk of coming back.
Jonesboro, ArkansasAges 18 years+ - NCT07242391Recruiting
Menopausal hormone therapy and heart function study
This study looks at how menopausal hormone therapy might affect the heart's pumping ability. It may help women who are naturally entering menopause understand if hormone therapy can protect their heart health.
Rochester, MinnesotaAges 45–60 - NCT05442463Recruiting
Hormone effects on blood vessel narrowing in kidneys and arteries
This study looks at how hormone treatments (estrogen, progesterone, or testosterone) may affect how blood vessels tighten in the body, including in the kidneys. Researchers measure these effects to understand potential impacts on blood flow and blood vessel control.
Calgary, AlbertaAges 18–90 - NCT06083766Recruiting
Hormone Therapy Effects on Metabolism in Transgender Adults
This study looks at how long-term gender-affirming hormone therapy affects your body's metabolism and energy use. Researchers want to understand these changes better to improve care for transgender and gender-diverse people.
Rochester, MinnesotaAges 18–40 - NCT06280560Recruiting
IVF hormones and womb lining health study
This study looks at how IVF hormone treatments affect the womb lining and whether they cause aging cells to build up. It may help doctors improve IVF success rates.
ValenciaAges 18–45 - NCT06704516RecruitingPhase 1
HRT and fatty liver disease in menopausal women – a pilot study
This study tests whether starting hormone replacement therapy (HRT) improves liver health in women with menopause and fatty liver disease (MASLD). It aims to understand how HRT might help reduce fat in the liver.
Oxford, OxfordshireAges 18 years+ - NCT06461793RecruitingPhase 2
Higher dose radiation with hormone therapy for high-risk prostate cancer
This trial tests a higher dose of radiation given in fewer sessions (hypofractionated) combined with hormone therapy for men with high-risk prostate cancer that has not spread. A gel spacer called SpaceOAR is used to protect the rectum. The goal is to see if this approach is safe and effective.
SeoulAges 20 years+ - NCT06679816RecruitingPhase 4
Hydrocortisone for hormone replacement in large pituitary tumor surgery
This trial tests hydrocortisone as hormone replacement therapy after surgery for large pituitary tumors. It aims to help patients maintain healthy cortisol levels during recovery.
Beijing, Beijing MunicipalityAges 18–70 - NCT05831709Recruiting
Hormone therapy and supervised exercise in menopausal women
This study looks at how hormone replacement therapy and a supervised exercise program may change body composition, heart health risk, and insulin sensitivity in postmenopausal women. It may help participants understand which combination works best for metabolic and cardiovascular health after menopause.
GhentAges 45–65 - NCT06369610RecruitingPhase 2
Less hormone therapy with radiation for prostate cancer
This trial tests whether some men with high-risk prostate cancer can safely receive less hormone therapy when combined with radiation. It aims to reduce side effects while still effectively treating the cancer.
Scottsdale, ArizonaAges 18 years+ - NCT06504953Recruiting
Knee movement study in women with and without hormone therapy
This study measures knee movement in healthy women ages 18-40 to see if hormone therapy affects it. You will need to come in on a specific day of your menstrual cycle.
Nice, Alpes-MaritimesAges 18–40 - NCT07077876Recruiting
Endometrial cancer and hyperplasia with conservative treatment
This study looks at women with endometrial adenocarcinoma or atypical hyperplasia who had conservative treatment instead of radical surgery. It aims to check how well the treatment works for both cancer and future pregnancy outcomes.
RomaAges 18 years+ - NCT07152366RecruitingPhase 4
Hormone and tetuzumab for active thyroid eye disease
This trial tests a new sequence of hormone therapy followed by a targeted drug (tetuzumab) for people with moderate to severe thyroid eye disease that is still active after steroid treatment didn't help enough.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07152340RecruitingPhase 4
Sequential hormone and IBI311 therapy for active TAO
This trial tests a two-step treatment for active, moderate-to-severe thyroid eye disease (TAO). You will first receive hormone therapy, followed by a drug called IBI311. The goal is to see if this sequence works better for people who have not had steroid treatment before.
Changhua, Shanghai MunicipalityAges 18–80 - NCT06570460RecruitingPhase 4
Estrogen pills vs. patch for Turner syndrome
This study compares two ways of taking estrogen (pills or a skin patch) in women with Turner syndrome to see which works better over time. It also includes healthy women for comparison.
Aarhus, Aarhus NAges 18–50 - NCT05717166RecruitingPhase 3
Stereotactic radiation for limited metastases with a main tumor
This trial tests whether a precise type of radiation can control cancer that has spread to a limited number of sites (1–10) while you also have the main tumor. It aims to improve outcomes by treating all visible cancer spots with stereotactic ablative radiotherapy.
Prince George, British ColumbiaAges 18 years+
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Common questions
- Are there clinical trials for hormone therapy?
- Yes. Clin2 currently lists 130 recruiting hormone therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hormone therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hormone therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.