Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06846554RecruitingPhase 2
Study of APL-9796 for Pulmonary Hypertension with CardioMEMS Monitor
This trial tests a study drug called APL-9796 for people with pulmonary hypertension (PH). It may help by using your CardioMEMS monitor to see how well the drug works. You can take part only if you have a CardioMEMS implant and your PH is not too mild or too severe.
London, LondonAges 18–80 - NCT06843577Recruiting
Handgrip therapy for high blood pressure
This trial tests if a simple handgrip exercise device can help lower blood pressure in people with elevated blood pressure or hypertension. You will use the device at home and have regular check-ups to see how well it works.
Valley Village, CaliforniaAges 22 years+ - NCT06827535Enrolling by invitation
Long-term study of eye changes in glaucoma and high eye pressure
This study tracks changes in blood flow, structure, and vision over time in people with glaucoma or high eye pressure. It aims to understand how these conditions progress, which could help improve future treatment.
Milan, ItalyAges 18 years+ - NCT06834230RecruitingPhase 4
Testing dotinurad for high uric acid in people with high blood pressure
This study tests a medicine called dotinurad to see if it helps lower high uric acid levels in people who also have high blood pressure. It may be an option if you have not taken uric acid lowering drugs recently or have been off them for over 27 days.
Saga, Saga-kenAges 20 years+ - NCT06823947RecruitingPhase 1
Study of KK3910 in healthy people and those with high blood pressure
This study tests a new medicine called KK3910, first in healthy volunteers to check safety, then in Japanese patients with essential hypertension (high blood pressure) to see if it helps lower blood pressure.
Hakata, FukuokaAges 18–80 - NCT06804161RecruitingPhase 3
Testing SGLT2 Inhibitors for Heart Health in Hypertension
This trial tests whether an SGLT2 inhibitor (a type of diabetes drug) can help prevent heart attacks, strokes, and other heart problems in people with high blood pressure. You may be eligible if you are 60 or older, have high blood pressure, and have had a heart or blood vessel event (like a heart attack or stroke) or have certain risk factors (like smoking, high cholesterol, or obesity).
Lübeck, Schleswig-HolsteinAges 60 years+ - NCT06808321Enrolling by invitation
Benidipine for high blood pressure or chest pain
This study looks at how well Benidipine works for people with high blood pressure or stable chest pain from heart disease. If you are already taking Benidipine for at least a month, this trial may help doctors learn more about its benefits.
AntalyaAges 18–80 - NCT06804122Recruiting
Exercise rehab for pulmonary arterial hypertension
This trial tests a supervised exercise program for people with pulmonary arterial hypertension (PAH), a type of high blood pressure in the lungs. It aims to see if regular exercise can improve your daily function and quality of life.
Tampere, PirkanmaaAges 18 years+ - NCT06797193Recruiting
Ultrasound technique to find liver blood pressure
This trial tests a new ultrasound technique called SHAPE to see if it can detect high blood pressure in the liver (portal hypertension) without needing an invasive procedure. It may help people who are already scheduled for a standard liver pressure measurement.
Scottsdale, ArizonaAges 18 years+ - NCT05530512Recruiting
Acupuncture for mild to moderate high blood pressure
This study tests whether acupuncture can help lower blood pressure in people with mild to moderate hypertension. You may be asked to join because you meet age and blood-pressure ranges and have a normal heart screening ECG.
Irvine, CaliforniaAges 45–75 - NCT04126785Recruiting
Exercise program for older adults with controlled high blood pressure
This trial compares two types of water-based exercise—short, intense bursts versus a steady, moderate pace—in older adults with high blood pressure that is already being controlled. It may help determine which exercise style lowers blood pressure and is easier or safer to stick with.
Bauru, São PauloAges 60 years+ - NCT06770023RecruitingPhase 1
Bridge to lung transplant with ECMO for right heart failure
This study tests a special heart-lung support machine (ECMO) for people waiting for a lung transplant whose heart is failing due to high blood pressure in the lungs. The machine helps rest the heart and lungs until transplant surgery.
Jacksonville, FloridaAges 18–80 - NCT06558877Recruiting
Pharmacist-led program for better blood pressure control
This trial tests if a pharmacist-led program with regular follow-ups and support can help people with high blood pressure get better control over their condition. It may be a good fit if you have high blood pressure that is not well controlled despite taking medication.
Xi'an, ShaanxiAges 18–80 - NCT06751082Recruiting
Sotatercept for pulmonary hypertension study
This study looks at how well the drug Sotatercept works for people with pulmonary hypertension (high blood pressure in the lungs) in a real-world clinic setting. If you are already taking Sotatercept, you may be able to join.
Rochester, MinnesotaAges 18 years+ - NCT06495970Recruiting
Pulmonary artery denervation for heart failure with lung hypertension
This trial tests a procedure called pulmonary artery denervation (PADN) for people with heart failure and a certain type of high blood pressure in the lungs (pulmonary hypertension Group 2). The goal is to see if using a special device called the Gradient Denervation System can help control the high pressures and improve your symptoms.
BadalonaAges 22–85 - NCT06730230Recruiting
Remote monitoring and health coaching for Latinx patients with high blood pressure
This study tests if using a home blood pressure monitor plus support from a community health worker can help Latinx patients better manage their high blood pressure. You may be able to join if you have trouble keeping your blood pressure under control.
New York, New YorkAges 18 years+ - NCT06309511Recruiting
Heart health and blood pressure study
This trial looks at how well the heart's inner layer is getting oxygen in people with high blood pressure. It may help doctors understand heart risk better.
Mascalucia, CataniaAges 18 years+ - NCT06703801Enrolling by invitation
Tracking pulmonary hypertension and quality of life
This study is tracking people with pulmonary hypertension (high blood pressure in the lungs) over time to see how their condition and quality of life change. By joining, you help doctors better understand the disease and improve care for others like you.
Hong KongAges 19 years+ - NCT05479461Recruiting
Phone-based blood pressure care vs usual care
This trial tests whether a technology-enabled program (using a smartphone) helps lower blood pressure better than standard care. It may help you manage high blood pressure with guided treatment changes.
Palo Alto, CaliforniaAges 30–90 - NCT06108674Recruiting
Phone-based pharmacist help for high blood pressure in seniors
This trial tests if a pharmacist can help older adults with uncontrolled high blood pressure manage it better through phone calls. It might be a good fit if you have a cell phone and your blood pressure is not under control.
Vitória da Conquista, Estado de BahiaAges 60 years+ - NCT06669806Recruiting
TIPS Stent Graft for Cirrhosis Complications
This study tests a TIPS stent graft (a tiny mesh tube placed in the liver to relieve pressure) for people with cirrhosis and complications like bleeding or fluid buildup. It aims to see how well it works and if it's safe.
Changsha, HunanAges 18–75 - NCT06659900Enrolling by invitation
Finding undiagnosed high blood pressure in Nigeria
This study is looking for adults in Nigeria who may have high blood pressure but haven't been diagnosed yet. It tests a community-based approach to find people with undiagnosed hypertension so they can get care.
EnuguAges 18 years+ - NCT06647745RecruitingPhase 3
Study for type 2 diabetes and high blood pressure
This study tests a new combination of three medications (THP-00101, THP-00102, and THP-00103) for people with type 2 diabetes and essential high blood pressure. It aims to see if this combination is safe and effective compared to standard treatments.
SeoulAges 19 years+ - NCT06646354Enrolling by invitationPhase 3
Study of two experimental drugs for high blood pressure and cholesterol
This trial tests whether taking two experimental drugs together can safely lower both high blood pressure and high cholesterol. It may be an option if you have both conditions and your blood pressure is not extremely high.
SeoulAges 19 years+
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.