Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 982 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Tucson, ArizonaAges 18–85 - NCT07768644Recruiting
Nailfold microscope study for pulmonary hypertension
This study uses a special microscope to look at the tiny blood vessels at the base of your fingernails. It aims to see if these vessels can help doctors understand and monitor pulmonary hypertension, a condition of high blood pressure in the lungs.
Clydebank, West DunbartonshireAges 18 years+ - NCT04991454RecruitingPhase 2
Xenon mri to image lung blood flow in pulmonary hypertension
This trial uses a special MRI scan with xenon gas to take detailed images of how blood moves through your lungs. It aims to see if this imaging can help doctors better understand and manage pulmonary hypertension, which is high blood pressure in the lungs.
Durham, North CarolinaAges 18–75 - NCT04454203RecruitingPhase 4
Local anesthetic catheter to reduce tourniquet-related blood pressure spikes
This Phase 4 trial tests whether a local anesthetic catheter placed near a nerve and artery can prevent high blood pressure caused by a tourniquet during total ankle replacement surgery. If it works, it may make recovery safer and more comfortable for some patients.
Durham, North CarolinaAges 18–75 - NCT04137549Recruiting
Monitoring nighttime blood pressure to reach target levels
This registry study looks at how well people can control high blood pressure during sleep. It may help your care team understand what changes support safer nighttime blood pressure targets.
Shanghai, Shanghai MunicipalityAges 50–79 - NCT07147114RecruitingPhase 4
Combined macitentan and dapagliflozin for heart failure with lung high blood pressure
This trial tests whether adding two medications—macitentan and dapagliflozin—together is safe and effective for people with heart failure and a certain type of high blood pressure in the lungs. It might help improve your symptoms and daily function.
BusanAges 19 years+ - NCT07254078Recruiting
Registry for chronic thromboembolic pulmonary hypertension patients
This study is a registry that collects information about people with chronic thromboembolic pulmonary hypertension (CTEPH). It helps doctors learn more about how this condition affects patients over time and how it is treated.
MoscowAges 18 years+ - NCT07599579Recruiting
Mobile app to manage high blood pressure after pregnancy complications
This study tests a smartphone app to help women who had high blood pressure during pregnancy manage their blood pressure now, 10–20 years later. The goal is to see if the app helps keep blood pressure under control and reduces heart disease risk.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07728643Recruiting
Blood vessel particles in children with new high blood pressure
This study looks at tiny particles in the blood (called extracellular vesicles) that may signal early blood vessel changes in children with new high blood pressure. If your child is between 6 and 17, has just been diagnosed with high blood pressure and hasn't started treatment, and is otherwise healthy, this trial may help doctors better understand how high blood pressure affects kids.
OsijekAges 6–17 - NCT07728656Recruiting
Trial on blood vessel markers in pregnancy with high blood pressure
This study looks at tiny particles released from blood vessels in pregnant women with high blood pressure. The goal is to find better ways to detect and manage conditions like preeclampsia.
OsijekAges 18 years+ - NCT03206814Recruiting
Mobile app coaching to improve high blood pressure control
This trial tests whether a smartphone app with remote care (telecare) can help people with hard-to-control high blood pressure reach better blood pressure numbers. It may help you and your care team monitor progress more closely at home.
Bahía BlancaAges 18–80 - NCT03457168Recruiting
Testing treatment for high blood pressure during sleep
This study looks at how to manage high blood pressure specifically during sleep, aiming to lower the risk it can cause over time. It may help you if your blood pressure readings stay high at night even if you’re otherwise able to function normally.
Ourense, OrenseAges 18 years+ - NCT04520048Recruiting
Blood vessel tests to predict preeclampsia worsening in pregnancy
This study measures blood vessel–related markers in pregnant people who already have high blood pressure or early preeclampsia. The goal is to predict who is more likely to get worse, so care can be better targeted.
Bobigny, Seine Saint DenisAges 18–40 - NCT04752293Recruiting
Study of a kidney blood-pressure system in kids
This study looks at how a kidney-related blood-pressure system works in children and teenagers, comparing those with newly diagnosed primary (no known cause) high blood pressure to those with normal blood pressure. It may help doctors better understand childhood blood-pressure changes and guide future care.
Winston-Salem, North CarolinaAges 7–18 - NCT05566002Recruiting
AI review of test results for pulmonary hypertension
This trial uses an artificial intelligence tool to look at results from tests used to evaluate pulmonary hypertension. It may help doctors make sense of your past test results, especially heart and lung evaluation results.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05584722Recruiting
Study risk and resilience in pulmonary arterial hypertension
This study looks at how people with pulmonary arterial hypertension (PAH) and certain genetic risks cope and how their bodies respond over time. It may help researchers understand factors linked to better or worse outcomes, and how different people manage the condition.
Nashville, TennesseeAges 15–80 - NCT05826925Recruiting
Care planning for women after pregnancy-related high blood pressure
This study tests ways to improve cardiovascular (heart and blood vessel) care for women after they had high blood pressure during pregnancy. It may help you get better guidance to prevent future heart problems.
Salt Lake City, UtahAges 18 years+ - NCT05958901Recruiting
Study of pulmonary hypertension in everyday clinical care
This observational study is looking at people diagnosed with pulmonary hypertension to better understand how it behaves over time. You may help researchers by allowing repeated check-ins for years and sharing symptom and test information.
Guangzhou, GuangdongAges 20–70 - NCT06105775Recruiting
Nitrate supplement for high blood pressure in pregnancy
This trial tests if a nitrate supplement (similar to beetroot) can help control chronic high blood pressure in early pregnancy. It is for women already taking methyldopa and enrolled before 16 weeks.
Ribeirão Preto, São PauloAges 18 years+ - NCT06133322Recruiting
Blood pressure study for church communities in New Orleans
This study looks at different ways to lower blood pressure in church communities. It aims to find the best methods to reduce high blood pressure, especially in groups that are often affected by it.
New Orleans, LouisianaAges 18 years+ - NCT06169241RecruitingEarly Phase 1
Nitrate supplement for resistant hypertension
This trial tests whether a natural nitrate supplement (like beetroot juice) can help lower blood pressure and improve blood vessel function in people with resistant hypertension. If you have resistant hypertension and your medications have been stable for at least 30 days, you may be eligible.
Rio de JaneiroAges 18–75 - NCT06187012Recruiting
Long-term heart health after pregnancy
This study checks if having high blood pressure years after pregnancy is linked to long-term health. It involves a visit and possibly an MRI scan of your heart and blood vessels.
OxfordAges 30–70 - NCT06228677Recruiting
Catecholamine levels during adrenal artery embolization
This trial measures hormone levels in blood during a procedure to treat high blood pressure caused by an adrenal gland problem. It may help doctors understand how the body responds during treatment.
Chengdu, SichuanAges 18 years+ - NCT06388421Recruiting
PH-ILD patient registry: tracking real-world outcomes
This study tracks people with both lung scarring and high blood pressure in the lungs (Group 3 PH-ILD) to better understand the disease and how treatments like Tyvaso work in real life. It may help you and your doctor make more informed decisions about your care.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 982 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.