Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06580613Recruiting
Better blood pressure management in primary care
This trial tests a new way to manage high blood pressure in primary care. It aims to help people better control their blood pressure using home monitoring and digital tools.
HelsingborgAges Any age - NCT06527794Recruiting
Remote blood pressure management for Black patients
This study tests a remote program to help Black patients manage high blood pressure from home. You would use a blood pressure monitor and have phone or video visits with your care team.
Winston-Salem, North CarolinaAges 21–85 - NCT06468202RecruitingPhase 4
Aspirin dose study to prevent high blood pressure in pregnancy
This trial compares two doses of aspirin to see which is better at preventing conditions like preeclampsia (a serious form of high blood pressure during pregnancy). You may qualify if you are in early pregnancy and have certain risk factors.
Birmingham, AlabamaAges 14–35 - NCT04520048Recruiting
Blood vessel tests to predict preeclampsia worsening in pregnancy
This study measures blood vessel–related markers in pregnant people who already have high blood pressure or early preeclampsia. The goal is to predict who is more likely to get worse, so care can be better targeted.
Bobigny, Seine Saint DenisAges 18–40 - NCT06388421Recruiting
PH-ILD patient registry: tracking real-world outcomes
This study tracks people with both lung scarring and high blood pressure in the lungs (Group 3 PH-ILD) to better understand the disease and how treatments like Tyvaso work in real life. It may help you and your doctor make more informed decisions about your care.
Birmingham, AlabamaAges 18 years+ - NCT06187012Recruiting
Long-term heart health after pregnancy
This study checks if having high blood pressure years after pregnancy is linked to long-term health. It involves a visit and possibly an MRI scan of your heart and blood vessels.
OxfordAges 30–70 - NCT06169241RecruitingEarly Phase 1
Nitrate supplement for resistant hypertension
This trial tests whether a natural nitrate supplement (like beetroot juice) can help lower blood pressure and improve blood vessel function in people with resistant hypertension. If you have resistant hypertension and your medications have been stable for at least 30 days, you may be eligible.
Rio de JaneiroAges 18–75 - NCT06133322Recruiting
Blood pressure study for church communities in New Orleans
This study looks at different ways to lower blood pressure in church communities. It aims to find the best methods to reduce high blood pressure, especially in groups that are often affected by it.
New Orleans, LouisianaAges 18 years+ - NCT06105775Recruiting
Nitrate supplement for high blood pressure in pregnancy
This trial tests if a nitrate supplement (similar to beetroot) can help control chronic high blood pressure in early pregnancy. It is for women already taking methyldopa and enrolled before 16 weeks.
Ribeirão Preto, São PauloAges 18 years+ - NCT06059638Recruiting
Pacemaker pacing for blood pressure control
This study tests whether adjusting the timing of a pacemaker can help lower blood pressure in people who already have or need a pacemaker. It could be an option for those whose blood pressure is not well controlled with medication.
Scottsdale, ArizonaAges 18 years+ - NCT05826925Recruiting
Care planning for women after pregnancy-related high blood pressure
This study tests ways to improve cardiovascular (heart and blood vessel) care for women after they had high blood pressure during pregnancy. It may help you get better guidance to prevent future heart problems.
Salt Lake City, UtahAges 18 years+ - NCT05584722Recruiting
Study risk and resilience in pulmonary arterial hypertension
This study looks at how people with pulmonary arterial hypertension (PAH) and certain genetic risks cope and how their bodies respond over time. It may help researchers understand factors linked to better or worse outcomes, and how different people manage the condition.
Nashville, TennesseeAges 15–80 - NCT04752293Recruiting
Study of a kidney blood-pressure system in kids
This study looks at how a kidney-related blood-pressure system works in children and teenagers, comparing those with newly diagnosed primary (no known cause) high blood pressure to those with normal blood pressure. It may help doctors better understand childhood blood-pressure changes and guide future care.
Winston-Salem, North CarolinaAges 7–18 - NCT04991454RecruitingPhase 2
Xenon mri to image lung blood flow in pulmonary hypertension
This trial uses a special MRI scan with xenon gas to take detailed images of how blood moves through your lungs. It aims to see if this imaging can help doctors better understand and manage pulmonary hypertension, which is high blood pressure in the lungs.
Durham, North CarolinaAges 18–75 - NCT04454203RecruitingPhase 4
Local anesthetic catheter to reduce tourniquet-related blood pressure spikes
This Phase 4 trial tests whether a local anesthetic catheter placed near a nerve and artery can prevent high blood pressure caused by a tourniquet during total ankle replacement surgery. If it works, it may make recovery safer and more comfortable for some patients.
Durham, North CarolinaAges 18–75 - NCT01884051Recruiting
Study of blood and skin changes in pulmonary hypertension
This study looks at how hormones, metabolism, and body signals relate to pulmonary arterial hypertension. You may be eligible if you (or a family member) have idiopathic, inherited, or related pulmonary arterial hypertension, and you can do required blood and other testing.
Nashville, TennesseeAges Up to 90 years - NCT07877272Recruiting
Better liver testing for high-risk fatty liver disease
This study tests a more detailed way to examine the liver in people with fatty liver disease who also have other health risks. The doctors want to see if this extra testing helps decide whether you need treatment.
MünsterAges 18 years+ - NCT07115953Recruiting
Spiral nerve treatment for uncontrolled high blood pressure
This trial tests a new procedure to treat high blood pressure by using a special catheter to calm overactive nerves in your kidneys. It may help you achieve better blood pressure control if medications are not enough.
MelbourneAges 18 years+ - NCT01712620RecruitingPhase 2
Spironolactone for pulmonary arterial hypertension
This study tests whether spironolactone, a water pill that helps the heart and blood vessels, can improve symptoms in people with pulmonary arterial hypertension (PAH), a condition of high blood pressure in the lungs. It's a phase 2 trial, meaning it's early but may offer a new treatment option.
Bethesda, MarylandAges 18–100 - NCT07589387Recruiting
Combined care for diabetes and blood pressure in Nigeria
This study looks at how to improve care for people who have both diabetes and high blood pressure in Nigeria. It aims to help patients manage their conditions better by offering integrated treatment and support.
AbajiAges 18 years+ - NCT05798923RecruitingPhase 2
Study of a new drug for pulmonary hypertension with lung disease
This trial tests an investigational drug called LAM-001 for people who have pulmonary hypertension (high blood pressure in the lungs) along with a type of lung disease called interstitial lung disease. The drug may help improve symptoms and daily function. This study will see if the drug is safe and helpful for this condition.
Tucson, ArizonaAges 18–85 - NCT07876544RecruitingPhase 4
New drug plus amlodipine for high blood pressure and early kidney damage
This trial tests a new medicine (sitogilun malate) combined with a standard blood pressure drug (amlodipine) to see if it protects the kidneys in people with early kidney damage caused by high blood pressure. Participation could help prevent further kidney damage while controlling your blood pressure.
Shanghai, ChinaAges 18 years+ - NCT07876479Recruiting
Comparing kidney nerve treatment times for high blood pressure
This study tests whether the length of time used for a kidney nerve treatment (renal denervation) affects how well it lowers blood pressure. It may help people whose blood pressure is still high despite taking medications.
ShanghaiAges 20–80 - NCT07686120RecruitingPhase 3
Baxdrostat for uncontrolled high blood pressure
This trial tests a new medicine called baxdrostat for people whose blood pressure stays high even when they take two or more medicines. It will be added to your current blood pressure pills to see if it helps lower your blood pressure more.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.