Clinical trials
Intensive Care Patients clinical trials
Below are recruiting intensive care patients clinical trials, each written for real people, not researchers. We’re tracking 408 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07469072RecruitingPhase 2
Nafamostat doses for dialysis blood thinning in ICU
This trial is testing different doses of a blood thinner called nafamostat in patients who are in the ICU and need continuous kidney dialysis (CRRT). The goal is to find which dose works best to prevent clots in the dialysis machine without causing bleeding problems.
Guangzhou, GuangdongAges 18–80 - NCT07372924RecruitingPhase 2
Medicine for comfort during extended breathing tube use in the ICU
This trial tests a medicine called tegileridine fumarate to help patients who need a breathing tube for a long time in the ICU feel more comfortable. It may be an option if you or your loved one have been on a ventilator for several days.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT07735182Recruiting
Gut bacteria and organ damage in sepsis
This study looks at how bacteria in your gut and other signs in your body affect liver and kidney damage in people with sepsis. It also compares findings to healthy volunteers to see what is different.
Hangzhou, ZhejiangAges 18 years+ - NCT07732244Recruiting
Testing a wireless brain oxygen monitor in the NICU
This study is testing a new wireless device that monitors oxygen levels in the brain. It is for babies already using a similar wired monitor, to see if the wireless version works just as well.
Montreal, QuebecAges Any age - NCT07707765Recruiting
Early help after sepsis in the ICU to prevent PTSD
This study tests whether early psychological support after sepsis in the ICU can reduce the chance of developing posttraumatic stress disorder (PTSD). If you recently left the ICU after sepsis, you may be able to join.
AshkelonAges 18–120 - NCT03720860Recruiting
Study inflammatory signals in sudden kidney injury in ICU
This study looks at substances related to inflammation to better understand sudden kidney problems in people who are very sick in the ICU. It may help improve how kidney injury is predicted and treated after severe illness or major events.
Uppsala, Uppsala CountyAges 18 years+ - NCT04507737Recruiting
Rapid response teams for hospitalized patients: who benefits
This trial looks at how hospital rapid response teams should be used and which hospitalized patients benefit most. If you’re an adult on a general ward and need urgent help, the study may help hospitals respond faster in the future.
Hillerød, DanmarkAges 18 years+ - NCT04670744Recruiting
Uses routine hospital records to find key care outcomes
This study looks at routinely collected anesthesia and intensive care information in hospital systems to find which signs and events best predict outcomes. It may help future patients by improving how care teams monitor and evaluate treatment.
Berlin, State of BerlinAges Up to 120 years - NCT04910841Recruiting
Testing a glucose-monitoring device in septic shock ICU
This trial checks whether a continuous glucose monitoring system (“CGM GUARDIAN 2”) can be used safely and effectively for people in the ICU who have septic shock and high blood sugar. It may help the medical team track blood sugar more easily while you receive insulin.
NiceAges 18 years+ - NCT05124977Recruiting
Antibiotic plan study for ventilator pneumonia in ICU
This trial tests an “antibiotic stewardship” approach—choosing and adjusting antibiotics in a smarter way—for a first episode of pneumonia in patients on a breathing machine. It may help ensure the right antibiotics are used at the right time, while avoiding unnecessary or overly broad treatment.
Clichy-sous-BoisAges 18 years+ - NCT05211661Recruiting
Study breathing muscle changes in people on a ventilator
This study looks at how the diaphragm (a key breathing muscle) changes during and after being on a breathing machine in the ICU. It may help researchers understand why breathing can get weaker after ventilation and how to measure it safely (including with MRI).
AachenAges 18–75 - NCT05247502Recruiting
Study of kidney outcomes after ICU kidney injury
This study follows adults who stay in the ICU for more than 24 hours to see how an episode of acute kidney failure affects kidney health over the long term. Your participation helps researchers understand which ICU patients may need closer kidney monitoring later.
Clermont-FerrandAges 18 years+ - NCT05263674RecruitingPhase 3
Faster ICU treatment for non-convulsive seizures in adults
This study compares two ways to stop non-convulsive seizures in the ICU. It tests whether fast sedation in intensive care works better than giving higher-dose anti-seizure medicine through a vein.
AarhusAges 18–120 - NCT05357170Recruiting
Testing gut bacteria changes after severe ICU illnesses
This study looks at changes in the microbiome (gut bacteria) in adults after serious ICU illnesses like sepsis, major trauma, or open heart/abdominal surgery. It may help researchers understand why recovery can be harder in some people and guide future treatments.
Gainesville, FloridaAges 18–110 - NCT05371886Recruiting
Testing how morphine (with or without midazolam) behaves in NICU babies
This study measures how morphine works in very young babies, and whether adding midazolam changes how the medicines behave and affect the body. It may help doctors better choose and dose pain/sedation medicines for babies in intensive care.
BrestAges 5 months–10 months - NCT05451875Recruiting
Check how well a skin patch records vital signs in children
This study tests whether a small skin patch (connected to a device) can accurately record vital signs in children who need close monitoring in a pediatric intensive care unit (PICU). It may help improve how doctors track a child’s heart rate, breathing, and other key signs.
Montreal, QuebecAges 1 day–18 years - NCT05537298Recruiting
Help for muscle recovery after serious ICU illness
This trial looks at how to improve muscle strength and function after a stay in the ICU for sepsis or acute respiratory failure. If you recover from the illness but your muscles become weak, this study may test an approach to help rebuild strength faster.
Birmingham, AlabamaAges 18 years+ - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT05565222RecruitingPhase 3
Testing two antibiotics as alternatives for ICU severe ESBL infections
This study compares two antibiotics—piperacillin-tazobactam or temocillin—to treat severe ICU infections caused by certain hard-to-treat gut bacteria (ESBL). It may help patients avoid the use of carbapenem antibiotics like meropenem when the bacteria are susceptible.
ParisAges 18 years+ - NCT05606809Recruiting
Score brain injury after cardiac arrest ICU admission
This study compares different scoring methods to estimate early brain injury when people are admitted to the ICU after a cardiac arrest. It may help doctors choose the best early assessment approach for patients who are in a coma.
Nantes, Pays de LoireAges 18 years+ - NCT05660252Recruiting
Family conversations to reduce refusal of organ donation after ICU care
This study tests whether a structured, shared conversation between the clinical team and the patient’s family can reduce how often families refuse organ donation after life-sustaining treatment is stopped. If you are eligible, the trial may guide how consent discussions are handled during a difficult ICU decision.
Nantes, Pays de la Loire RegionAges 18 years+ - NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT05696093RecruitingPhase 3
Cotrimoxazole for step-down treatment of ventilator pneumonia
This trial tests whether switching from an initial antibiotic to cotrimoxazole (a specific antibiotic combination) can work as well—or better—for ventilator-associated pneumonia in ICU patients. It aims to see if “de-escalating” antibiotics can control the infection while keeping vital signs stable.
AmiensAges 18 years+ - NCT05844579Recruiting
Early breathing and mobilization support for ICU lung injury
This study looks at whether starting early movement and breathing-related care while in the ICU helps people with ARDS (a serious lung condition). You may be eligible if you recently needed a breathing machine and are expected to need it for a bit longer.
TokyoAges 16 years+
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Common questions
- Are there clinical trials for intensive care patients?
- Yes. Clin2 currently lists 408 recruiting intensive care patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intensive care patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intensive care patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.