Clinical trials
Intensive Care Unit clinical trials
Below are recruiting intensive care unit clinical trials, each written for real people, not researchers. We’re tracking 290 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07220733RecruitingPhase 1/Phase 2
Exoskeleton rehab after chest surgery in the ICU
This trial tests whether a self-balancing exoskeleton can help people who had chest surgery and are weak (bedbound or nearly so) start walking earlier in the ICU. It aims to see if it is safe and possible to use this device for rehabilitation.
Boston, MassachusettsAges 18 years+ - NCT07672106Recruiting
Predicting breathing tube need after major surgery recovery
This study watches patients after major surgery to see which factors may increase the chance of needing a breathing tube again. It helps doctors better predict and prevent breathing problems in the intensive care unit.
Istanbul, ŞişliAges 18 years+ - NCT07052123Recruiting
Blood pressure monitoring in ICU with DARE device
This trial tests a new non-invasive device (DARE) to measure blood pressure and core body temperature in patients who are already receiving standard monitoring with an arterial line and a urinary catheter in the ICU.
Saint-Denis, FranceAges 18 years+ - NCT07372924RecruitingPhase 2
Medicine for comfort during extended breathing tube use in the ICU
This trial tests a medicine called tegileridine fumarate to help patients who need a breathing tube for a long time in the ICU feel more comfortable. It may be an option if you or your loved one have been on a ventilator for several days.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT07744321Recruiting
Bacteria in stool during long ICU stays
This study looks at how certain bacteria (Klebsiella pneumoniae and Enterobacter cloacae) change over time in the stool of ICU patients staying at least 28 days. It aims to understand why these infections occur and how they evolve, which could help improve future care.
CaenAges 18 years+ - NCT07740304Recruiting
Blood flow test to predict survival in sepsis patients
This study checks if a simple blood flow measurement can help predict which patients with sepsis are at higher risk of dying within 28 days. The goal is to see if this test can guide treatment decisions in the ICU.
Edirne, MerkezAges 18 years+ - NCT07732244Recruiting
Testing a wireless brain oxygen monitor in the NICU
This study is testing a new wireless device that monitors oxygen levels in the brain. It is for babies already using a similar wired monitor, to see if the wireless version works just as well.
Montreal, QuebecAges Any age - NCT07718464Recruiting
AKI risk test for children in the ICU
This study tests a new way to find children in the pediatric ICU who are at risk for serious kidney injury early, so doctors can start treatment sooner. Your child's kidney stress markers will be checked from a blood or urine sample.
Cincinnati, OhioAges Any age - NCT07449416Recruiting
Ceribell Delirium Monitor Study in ICU Patients
This pilot study tests a special brain monitor (called Ceribell EEG) to see if it can help detect delirium in ICU patients. Delirium is a state of confusion that can happen during a serious illness, and this monitor may help doctors catch it early.
Irvine, CaliforniaAges 18 years+ - NCT04176094Recruiting
Trial of ICU overnight resident scheduling plans
This study tests whether changing how ICU residents are scheduled for overnight shifts affects training and ICU operations. It looks at participating adult ICU patients and the residents and staff who work overnight during the study periods.
Toronto, OntarioAges 18 years+ - NCT04278690Recruiting
Help parents safely give liquid medicines after NICU discharge
This study helps parents learn how to safely use their baby’s liquid medicines at home after a NICU stay. It may provide support and tools so medication is given correctly and follow-up care happens on time.
New York, New YorkAges 18 years+ - NCT04507737Recruiting
Rapid response teams for hospitalized patients: who benefits
This trial looks at how hospital rapid response teams should be used and which hospitalized patients benefit most. If you’re an adult on a general ward and need urgent help, the study may help hospitals respond faster in the future.
Hillerød, DanmarkAges 18 years+ - NCT04989790Recruiting
Early mobility program for critically ill children in the PICU
This trial tests whether a structured “early mobility” activity plan (“PICU Up!”) helps children who are on a breathing machine recover or feel better while in the pediatric ICU. It aims to see if starting safe movement earlier makes a difference for critically ill kids.
Madera, CaliforniaAges Up to 18 years - NCT04990908Recruiting
Screening children in ICU for immune problems after severe infection
This study checks children in pediatric intensive care for possible “immune system problems” after a severe infection. The goal is to find primary immunodeficiencies early, which may change follow-up and treatment for the child’s immune health.
MontpellierAges 3 months–16 years - NCT05357170Recruiting
Testing gut bacteria changes after severe ICU illnesses
This study looks at changes in the microbiome (gut bacteria) in adults after serious ICU illnesses like sepsis, major trauma, or open heart/abdominal surgery. It may help researchers understand why recovery can be harder in some people and guide future treatments.
Gainesville, FloridaAges 18–110 - NCT05451875Recruiting
Check how well a skin patch records vital signs in children
This study tests whether a small skin patch (connected to a device) can accurately record vital signs in children who need close monitoring in a pediatric intensive care unit (PICU). It may help improve how doctors track a child’s heart rate, breathing, and other key signs.
Montreal, QuebecAges 1 day–18 years - NCT05537298Recruiting
Help for muscle recovery after serious ICU illness
This trial looks at how to improve muscle strength and function after a stay in the ICU for sepsis or acute respiratory failure. If you recover from the illness but your muscles become weak, this study may test an approach to help rebuild strength faster.
Birmingham, AlabamaAges 18 years+ - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+ - NCT05565222RecruitingPhase 3
Testing two antibiotics as alternatives for ICU severe ESBL infections
This study compares two antibiotics—piperacillin-tazobactam or temocillin—to treat severe ICU infections caused by certain hard-to-treat gut bacteria (ESBL). It may help patients avoid the use of carbapenem antibiotics like meropenem when the bacteria are susceptible.
ParisAges 18 years+ - NCT05606809Recruiting
Score brain injury after cardiac arrest ICU admission
This study compares different scoring methods to estimate early brain injury when people are admitted to the ICU after a cardiac arrest. It may help doctors choose the best early assessment approach for patients who are in a coma.
Nantes, Pays de LoireAges 18 years+ - NCT05660252Recruiting
Family conversations to reduce refusal of organ donation after ICU care
This study tests whether a structured, shared conversation between the clinical team and the patient’s family can reduce how often families refuse organ donation after life-sustaining treatment is stopped. If you are eligible, the trial may guide how consent discussions are handled during a difficult ICU decision.
Nantes, Pays de la Loire RegionAges 18 years+ - NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT05696093RecruitingPhase 3
Cotrimoxazole for step-down treatment of ventilator pneumonia
This trial tests whether switching from an initial antibiotic to cotrimoxazole (a specific antibiotic combination) can work as well—or better—for ventilator-associated pneumonia in ICU patients. It aims to see if “de-escalating” antibiotics can control the infection while keeping vital signs stable.
AmiensAges 18 years+ - NCT05804773Recruiting
Studying brain blood flow changes when blood pressure changes
This study looks at how blood flow in the brain changes when blood pressure rises or falls in people in the ICU. It may help doctors understand safer ways to manage blood pressure in critically ill patients.
Paris, FranceAges 18 years+
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Common questions
- Are there clinical trials for intensive care unit?
- Yes. Clin2 currently lists 290 recruiting intensive care unit studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intensive care unit trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intensive care unit trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.