Clinical trials
Intensive Care Unit clinical trials
Below are recruiting intensive care unit clinical trials, each written for real people, not researchers. We’re tracking 278 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06296381Recruiting
Measuring normal muscle strength in ICU patients and healthy people
This study measures normal muscle strength in healthy people and ICU patients to create a reference guide. If you are healthy or in the ICU and can follow instructions, you may be able to help.
Recife, BrazilAges 18–90 - NCT06279793RecruitingPhase 2
Fish oil for recovery after high-risk heart surgery
This trial tests if giving fish oil through a vein before and after heart surgery can help patients recover faster. It is for people who have a high risk of complications during surgery.
AugsburgAges 18 years+ - NCT06260345Recruiting
Children with severe bacterial infections in intensive care
This trial looks at how children with severe bacterial infections that start outside the hospital are treated in the pediatric intensive care unit. It helps doctors learn more about these infections to improve care for kids.
CréteilAges Up to 18 years - NCT06229288RecruitingPhase 3
Pneumonia treatment: amoxicillin alone vs. with clavulanate for adults 65+
This trial compares two antibiotics for older adults hospitalized with pneumonia. It aims to see if amoxicillin alone works as well as amoxicillin combined with clavulanate, which might reduce side effects.
Saint-Nazaire, FranceAges 65 years+ - NCT05606809Recruiting
Score brain injury after cardiac arrest ICU admission
This study compares different scoring methods to estimate early brain injury when people are admitted to the ICU after a cardiac arrest. It may help doctors choose the best early assessment approach for patients who are in a coma.
Nantes, Pays de LoireAges 18 years+ - NCT06172491Recruiting
Automated tool to measure ICU delirium severity
This study tests a computerized tool that automatically measures how severe delirium (sudden confusion) is for ICU patients. Researchers want to see if it can help monitor and manage delirium better without adding extra work for nurses.
Rochester, MinnesotaAges 50 years+ - NCT06117345Enrolling by invitation
PICU Journal for Parents and Caregivers
This study tests a journal to help parents and caregivers stay involved while their child is in the pediatric intensive care unit (PICU). It aims to see if the journal improves communication and engagement.
Nashville, TennesseeAges 18 years+ - NCT06100978Recruiting
Patient experiences after severe seizures
This study interviews people who had a severe, prolonged seizure (status epilepticus) and were treated in intensive care. It asks how they feel and what they experienced 3 months to 5 years later.
AngoulêmeAges 18 years+ - NCT06054828Recruiting
Modified ICU program to prevent confusion
This trial tests a special program for people in the ICU who are on a breathing machine. The program aims to prevent confusion and help patients recover better.
Taipei, National Taiwan UniversityAges 18 years+ - NCT02539407Recruiting
Study drug levels in critically ill children
This trial measures how anti-infective medicines move through a child’s body while they are in the hospital or during follow-up. The goal is to better understand dosing and drug exposure in critically ill children.
ParisAges 1 day–18 years - NCT05950958Recruiting
Preventing ICU confusion with several supportive care steps
This trial tests whether a set of different care steps in the ICU can help prevent delirium, a sudden episode of confusion. It may help people who are at higher risk because they will likely need ICU care for more than a day.
SeoulAges 50 years+ - NCT05936710Recruiting
Citrate vs acetate dialysis to prevent low blood pressure
This study compares two types of dialysis fluid (citrate-based vs acetate-based) to see which better helps protect blood pressure during intermittent dialysis. It may help people in intensive care who are at risk of dialysis-related low blood pressure.
BéthuneAges 18 years+ - NCT05867472RecruitingPhase 3
Sedation plan for critically ill children on breathing machines
This Phase 3 trial tests a sedation approach using inhaled (“volatile”) anesthesia gases for children who need a ventilator. It aims to improve comfort and brain-related outcomes while they stay on the breathing machine for at least a day.
Hamilton, OntarioAges 1 month–18 years - NCT05804773Recruiting
Studying brain blood flow changes when blood pressure changes
This study looks at how blood flow in the brain changes when blood pressure rises or falls in people in the ICU. It may help doctors understand safer ways to manage blood pressure in critically ill patients.
Paris, FranceAges 18 years+ - NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+ - NCT05537298Recruiting
Help for muscle recovery after serious ICU illness
This trial looks at how to improve muscle strength and function after a stay in the ICU for sepsis or acute respiratory failure. If you recover from the illness but your muscles become weak, this study may test an approach to help rebuild strength faster.
Birmingham, AlabamaAges 18 years+ - NCT05409573Recruiting
Check oxygen monitoring during pre-intubation in the ICU
This study tests whether a specific oxygen level monitor (end-tidal oxygen, or EtO2) can be used during “preoxygenation” before breathing tube placement. It may help clinicians intubate more safely for people who urgently need a breathing tube due to serious breathing failure.
OrléansAges 18 years+ - NCT05357170Recruiting
Testing gut bacteria changes after severe ICU illnesses
This study looks at changes in the microbiome (gut bacteria) in adults after serious ICU illnesses like sepsis, major trauma, or open heart/abdominal surgery. It may help researchers understand why recovery can be harder in some people and guide future treatments.
Gainesville, FloridaAges 18–110 - NCT05279547Recruiting
Bed-cycle exercise study to test muscle oxygen during ICU care
This trial tests whether brief “interval” bed-cycling changes how well your leg muscles use oxygen compared with steady cycling. It’s meant for carefully selected ICU patients who can safely do active cycling while on ventilator support.
LeuvenAges 18 years+ - NCT04848090Enrolling by invitation
Genetic testing for newborns in the hospital intensive care unit
This study uses whole-genome sequencing (a DNA test that looks across the genome) for newborns in the intensive care unit when doctors suspect a genetic condition. It aims to help identify possible genetic causes of illness and improve understanding for families and clinicians.
Pittsburgh, PennsylvaniaAges Up to 1 year - NCT02118467RecruitingPhase 4
Testing medicines that raise blood pressure in ICU shock patients
This trial studies whether “blood pressure–supporting” medicines (given through a central line) work well and safely for adults in the ICU who have shock. Your team may use the results to improve care for people with low blood pressure and poor blood flow to organs.
Chicago, IllinoisAges 18 years+ - NCT04180397RecruitingPhase 4
Removing extra fluid in critically ill ICU patients with overload
This trial studies a medicine strategy to remove extra fluid from the body in ICU patients who have fluid overload. It aims to see whether controlled fluid removal is safer and better for recovery than usual care.
SydneyAges 18 years+ - NCT04243356Enrolling by invitation
ICU nurse involvement in a post-ICU follow-up clinic
This study looks at whether having ICU nurses actively involved in a follow-up clinic after ICU discharge improves patients’ recovery and follow-up care. It focuses on patients who were cared for in the ICU and the registered nurses who cared for them.
Ann Arbor, MichiganAges 18 years+
Hear when a new Intensive Care Unit trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for intensive care unit?
- Yes. Clin2 currently lists 278 recruiting intensive care unit studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intensive care unit trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intensive care unit trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.