Clinical trials
Intensive Care clinical trials
Below are recruiting intensive care clinical trials, each written for real people, not researchers. We’re tracking 442 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05371886Recruiting
Testing how morphine (with or without midazolam) behaves in NICU babies
This study measures how morphine works in very young babies, and whether adding midazolam changes how the medicines behave and affect the body. It may help doctors better choose and dose pain/sedation medicines for babies in intensive care.
BrestAges 5 months–10 months - NCT05395195RecruitingPhase 3
Erythropoietin for newborn brain injury in low-resource settings
This Phase 3 trial studies whether erythropoietin (a medicine related to red-blood-cell growth) can improve outcomes for newborns with moderate to severe brain injury after birth. The study focuses on babies born in low- and middle-income countries and aims to reduce harm from this early brain condition.
DhakaAges 1 hour–6 hours - NCT05449834RecruitingPhase 3
Testing early fibrinogen treatment after serious trauma bleeding
This Phase 3 study tests whether giving fibrinogen early can improve outcomes for adults with serious trauma who are actively bleeding. The goal is to help blood clotting work better sooner and potentially reduce complications from uncontrolled bleeding.
Newcastle, New South WalesAges 18–100 - NCT05451875Recruiting
Check how well a skin patch records vital signs in children
This study tests whether a small skin patch (connected to a device) can accurately record vital signs in children who need close monitoring in a pediatric intensive care unit (PICU). It may help improve how doctors track a child’s heart rate, breathing, and other key signs.
Montreal, QuebecAges 1 day–18 years - NCT05537298Recruiting
Help for muscle recovery after serious ICU illness
This trial looks at how to improve muscle strength and function after a stay in the ICU for sepsis or acute respiratory failure. If you recover from the illness but your muscles become weak, this study may test an approach to help rebuild strength faster.
Birmingham, AlabamaAges 18 years+ - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+ - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT05565222RecruitingPhase 3
Testing two antibiotics as alternatives for ICU severe ESBL infections
This study compares two antibiotics—piperacillin-tazobactam or temocillin—to treat severe ICU infections caused by certain hard-to-treat gut bacteria (ESBL). It may help patients avoid the use of carbapenem antibiotics like meropenem when the bacteria are susceptible.
ParisAges 18 years+ - NCT05606809Recruiting
Score brain injury after cardiac arrest ICU admission
This study compares different scoring methods to estimate early brain injury when people are admitted to the ICU after a cardiac arrest. It may help doctors choose the best early assessment approach for patients who are in a coma.
Nantes, Pays de LoireAges 18 years+ - NCT05660252Recruiting
Family conversations to reduce refusal of organ donation after ICU care
This study tests whether a structured, shared conversation between the clinical team and the patient’s family can reduce how often families refuse organ donation after life-sustaining treatment is stopped. If you are eligible, the trial may guide how consent discussions are handled during a difficult ICU decision.
Nantes, Pays de la Loire RegionAges 18 years+ - NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT05696093RecruitingPhase 3
Cotrimoxazole for step-down treatment of ventilator pneumonia
This trial tests whether switching from an initial antibiotic to cotrimoxazole (a specific antibiotic combination) can work as well—or better—for ventilator-associated pneumonia in ICU patients. It aims to see if “de-escalating” antibiotics can control the infection while keeping vital signs stable.
AmiensAges 18 years+ - NCT05807997Recruiting
Looking at outcomes of patients not admitted to ICU
This retrospective study reviews people who were evaluated by the general ICU team but were not admitted to the ICU between 2018 and 2023. It looks at their medical characteristics and outcomes to help understand who may or may not need ICU care.
Kfar SabaAges 18–99 - NCT05844579Recruiting
Early breathing and mobilization support for ICU lung injury
This study looks at whether starting early movement and breathing-related care while in the ICU helps people with ARDS (a serious lung condition). You may be eligible if you recently needed a breathing machine and are expected to need it for a bit longer.
TokyoAges 16 years+ - NCT05855252Recruiting
Study on monitoring and outcomes after moderate to severe head injury
This observational study follows adults with moderate to severe traumatic brain injury to understand care and outcomes. It collects information from the first 48 hours in the ICU and may help improve how clinicians monitor and treat patients in the critical early period.
Kogarah, New South WalesAges 18 years+ - NCT05860894Recruiting
Study of new ICU atrial fibrillation
This trial looks at people who develop a new irregular heart rhythm called atrial fibrillation while in the intensive care unit (ICU). It tests an approach to help with that condition after critical illness, aiming to improve outcomes for those affected.
BesançonAges 18 years+ - NCT05867472RecruitingPhase 3
Sedation plan for critically ill children on breathing machines
This Phase 3 trial tests a sedation approach using inhaled (“volatile”) anesthesia gases for children who need a ventilator. It aims to improve comfort and brain-related outcomes while they stay on the breathing machine for at least a day.
Hamilton, OntarioAges 1 month–18 years - NCT05889507RecruitingPhase 3
Cooling treatment for newborns with mild brain injury
This Phase 3 study tests whether cooling a newborn’s body can help babies with mild brain injury after a difficult birth. It aims to see if cooling improves brain-related outcomes compared with standard care.
NaplesAges 1 hour–6 hours - NCT05913531Recruiting
Use of past delirium data from adult patients
This trial looks back at information already collected from past patients, focusing on delirium (confusion that can happen during serious illness or after anesthesia). It doesn’t test a new treatment—its goal is to learn patterns from existing records to improve future care.
BerlinAges 18–100 - NCT05928767Recruiting
Using frailty scores to predict death in ICU sepsis
This trial checks whether a “frailty” rating (how physically/mentally vulnerable someone is) can predict the risk of death in ICU patients with sepsis shock. It may help doctors identify higher-risk patients earlier and tailor care.
BéthuneAges 18–65 - NCT05936710Recruiting
Citrate vs acetate dialysis to prevent low blood pressure
This study compares two types of dialysis fluid (citrate-based vs acetate-based) to see which better helps protect blood pressure during intermittent dialysis. It may help people in intensive care who are at risk of dialysis-related low blood pressure.
BéthuneAges 18 years+ - NCT05950958Recruiting
Preventing ICU confusion with several supportive care steps
This trial tests whether a set of different care steps in the ICU can help prevent delirium, a sudden episode of confusion. It may help people who are at higher risk because they will likely need ICU care for more than a day.
SeoulAges 50 years+ - NCT05984069Recruiting
Fatigue and frailty after ICU stay
This study looks at how feeling weak or frail after an ICU stay affects tiredness. It aims to find better ways to help people recover from serious illness.
Saint-EtienneAges 18 years+ - NCT05996211Recruiting
Swiss Study on Brain Development in Children with Heart Defects
This study follows children with severe heart problems born recently to see how their brain development progresses. It helps doctors understand what support these children might need as they grow.
BernAges 1 week–1 month
Hear when a new Intensive Care trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for intensive care?
- Yes. Clin2 currently lists 442 recruiting intensive care studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intensive care trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intensive care trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.