Clinical trials
Ischemia clinical trials
Below are recruiting ischemia clinical trials, each written for real people, not researchers. We’re tracking 211 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05244629Recruiting
Compare two stents for chronic artery-related gut pain
This trial tests whether an uncovered stent or a covered stent works better for treating chronic mesenteric ischemia (reduced blood flow to the intestines from artery narrowing). It’s meant for adults with symptoms and scans showing significant narrowing in a specific gut artery.
København ØAges 18 years+ - NCT05372718RecruitingPhase 3
Clot-busting drug versus surgery for sudden blocked leg arteries
This trial compares a clot-busting medicine (staphylokinase) against surgery in people with sudden, dangerous reduced blood flow to a leg. It may help find a safer or more effective way to restore circulation and prevent limb complications.
Kursk, Kursl RegionAges 18 years+ - NCT05549752RecruitingPhase 3
Flecainide vs amiodarone to treat fast heart rhythm in ER
This trial compares two medicines—flecainide and amiodarone—to help restore normal rhythm during an emergency visit for paroxysmal atrial fibrillation (a-fib). It’s aimed at people who also have coronary artery disease but no ongoing (residual) heart ischemia, and who have enough heart pumping strength.
AthensAges 18–85 - NCT05786001Recruiting
Test noninvasive checks of blood flow in limb-threatening ischemia
This study uses painless, noninvasive tests to measure blood flow in people with chronic limb-threatening ischemia. It may help doctors better understand circulation problems and track blood flow without procedures.
Tampere, PirkanmaaAges 18 years+ - NCT05830721Recruiting
Monitoring leg pressure in adults on life-support
This trial tests a device that continuously measures pressure in an arm or leg to help detect compartment syndrome in people on a heart-lung machine (VA-ECMO). It may help clinicians act sooner if pressure becomes dangerous, potentially reducing complications.
Baltimore, MarylandAges 18 years+ - NCT05854641RecruitingPhase 4
Stem cell treatment for poor blood flow in the leg ulcers
This trial tests whether a stem cell product (Stempeucel®) can improve healing and safety for people with critical limb ischemia caused by peripheral artery disease. It is for patients who cannot have (or have already tried) procedures to reopen blocked leg arteries and who have a leg ulcer and low blood-flow measurements.
Kuala LumpurAges 18–65 - NCT05854615RecruitingPhase 4
Stem cell treatment for painful poor blood flow in limbs
This trial tests whether a stem cell product (Stempeucel®) is safe and effective for people with Buerger’s disease causing critical limb ischemia and foot ulcers. It may help improve healing and blood flow when other options may be limited.
Kuala LumpurAges 18–65 - NCT06111599Recruiting
Thermovision-guided lumbar nerve block for severe leg pain
This trial tests a procedure called a lumbar sympathetic block (a numbing injection around nerves in your lower back) guided by a special heat-sensing camera. It aims to improve blood flow and reduce severe leg pain caused by chronic limb-threatening ischemia.
KošiceAges 20–80 - NCT06174597RecruitingEarly Phase 1
Stem cells for critical limb ischemia treatment
This trial tests whether stem cells from umbilical cord arteries can help people with severe leg pain or ulcers due to blocked arteries. It is for those who cannot have surgery or other procedures.
Nanjing, JiangsuAges 18–80 - NCT06178419Recruiting
Remote Conditioning for Brain Ischemia in Takayasu Arteritis
This trial tests whether gentle, repeated blood pressure cuff inflations on the arm can improve blood flow to the brain in people with Takayasu arteritis. It's for those with inactive disease and narrowed brain arteries but who still have low brain blood flow.
Beijing, Beijing MunicipalityAges 18–65 - NCT06238050Recruiting
Oxygen therapy for severe leg artery disease
This trial tests whether breathing pure oxygen at normal pressure can help people with severe, long-lasting lack of blood flow in their legs. It may offer a way to improve oxygen delivery to the leg and possibly avoid amputation.
AngersAges 18 years+ - NCT06255769Recruiting
Magnetic heart scan for diagnosing reduced blood flow
This study tests a new, noninvasive way to detect reduced blood flow to the heart (myocardial ischemia) using a magnetic heart scan called MCG. If you have chest pain or similar symptoms but your narrowed arteries are not severely blocked, this trial may help diagnose your condition more accurately.
Jinan, ShandongAges 18 years+ - NCT06271577Recruiting
Smartphone ECG for heart attack detection
This study tests whether a smartphone can take a 12-lead ECG (a heart tracing) quickly when someone arrives at the ER with chest pain, to help doctors spot a heart attack sooner.
Rochester, MinnesotaAges 18 years+ - NCT06277362Recruiting
New Leg-Saving Treatment for Critical Limb Ischemia
This study tests a new way to restore blood flow to the leg in people who have wounds or dead tissue on their foot and have run out of other treatment options. It's for those who have already tried angioplasty twice without success or have severely hardened small arteries.
Ancona, AnconaAges 18 years+ - NCT06296576Recruiting
Testing a new way to predict critical limb ischemia
This trial uses a Doppler ultrasound to measure blood flow speed in your leg arteries to see if it can better predict a severe form of peripheral artery disease called critical limb ischemia. You may qualify if you have known artery disease in your leg and are already scheduled for a toe blood pressure test.
CholetAges 18 years+ - NCT06482892RecruitingPhase 2
Testing a new drug for severe leg artery disease
This trial tests an experimental drug for people with critical limb ischemia, a serious condition where not enough blood reaches the legs. It aims to see if the drug can help with pain or healing of leg ulcers without the need for surgery.
Suzhou, JiangsuAges 18 years+ - NCT06544135Recruiting
Thermal camera study for blood flow in PAD with tissue loss
This study uses a special camera that detects heat to see blood flow in your leg before and after a procedure to open blocked arteries.
Beachwood, OhioAges 18–99 - NCT06705751Recruiting
Faster diagnosis of abnormal coronary artery origin
This study tests a new, faster way to diagnose an uncommon heart condition where one of the main arteries (the coronary artery) starts from the wrong place on the aorta. The goal is to help doctors find and treat it sooner.
San Donato Milanese, ItaliaAges 6 years+ - NCT06715878Recruiting
Robot-assisted surgery for small kidney tumors without cutting blood supply
This study tests a new, gentle way to remove small kidney tumors using a robot. The goal is to avoid cutting off blood supply to the kidney and to leave healthy tissue behind. It may help you keep more kidney function while still treating the cancer.
ShanghaiAges 15–80 - NCT06954610Recruiting
Heart Check for Stroke Risk in Atrial Fibrillation
This trial uses heart imaging to better understand stroke risk in people with atrial fibrillation (an irregular heartbeat). It may help doctors decide on the best treatment to prevent another stroke.
BernAges 18 years+ - NCT07059520Recruiting
Pressure test for blocked gut arteries (PRESSURE study)
This trial checks if a pressure measurement across a narrowed gut artery helps doctors decide if treatment is needed. It may help people with chronic gut artery blockages who are already scheduled for a procedure.
Enschede, OverijsselAges 18 years+ - NCT07068789Recruiting
Leg Artery Bypass: One vs. Multiple Vessels for Severe Limb Threat
This trial compares opening up one versus multiple blood vessels below the knee to improve blood flow in people with severe leg pain or wounds. It aims to find the best approach to save the limb and improve quality of life.
Sohag, Sohag GovernorateAges 40 years+ - NCT07324720Recruiting
Comparing ischemia vs plaque risk for high-risk artery disease
This trial compares two ways to decide which heart artery blockages need treatment: one looks at blood flow, the other at plaque buildup and risk. It's for people with high-risk blockages to see which approach leads to better outcomes.
Seoul, Main BuildingAges 19 years+ - NCT07352800RecruitingPhase 2
Study of APAC for peripheral artery disease and severe leg ischemia
This trial tests a new drug called APAC to see if it safely prevents blood clots and improves blood flow in people with narrowed leg arteries. It may help those with severe symptoms like pain at rest or non-healing wounds, or those with claudication (leg pain when walking).
HelsinkiAges Up to 85 years
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Common questions
- Are there clinical trials for ischemia?
- Yes. Clin2 currently lists 211 recruiting ischemia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ischemia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ischemia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.