Clinical trials
Joint Infection clinical trials
Below are recruiting joint infection clinical trials, each written for real people, not researchers. We’re tracking 46 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05169229RecruitingPhase 2
Antibiotic bone graft to prevent infection in hip replacement
This trial tests whether adding antibiotics to the bone graft used during hip replacement surgery can lower the risk of infection. It may help people who need a bone graft as part of their hip replacement.
Linköping, Region ÖstergotlandAges 18 years+ - NCT06428448RecruitingPhase 2
Antibiotic nail for ankle infection treatment
This study tests a special antibiotic-coated nail placed inside the ankle bone to treat infections. It may help people with ankle infections avoid more serious complications.
Lansing, MichiganAges 21 years+ - NCT06804265Recruiting
Better bacteria testing for joint implant infections
This study is testing a new, advanced lab test that can quickly identify exactly which bacteria are causing a joint implant infection. The goal is to help doctors choose the right antibiotics and improve treatment success.
BolognaAges 18 years+ - NCT04650607Recruiting
Phage therapy safety check in serious infection patients
This study checks the safety of using phage therapy (viruses that target certain bacteria) in adults being treated for serious infections. If you meet the safety rules, your care team may enroll you to help confirm phage treatment is safe.
LyonAges 18 years+ - NCT07473089Recruiting
Swiss study on joint replacement revision for infection
This study looks at people who need a second (revision) surgery on a large joint replacement like a hip, knee, shoulder, ankle, or elbow because of a suspected or confirmed infection. The goal is to learn more about these infections and improve care.
AarauAges 18 years+ - NCT06782295RecruitingPhase 4
Comparing two implant types in knee revision surgery
This study compares two types of knee implants (CCK vs PS) used during revision total knee replacement. The goal is to see which one works better in patients who need a second knee surgery.
Chicago, IllinoisAges 18 years+ - NCT05361941Recruiting
Antibiotic graft to help bone regrow in infected knee surgery areas
This trial tests an antibiotic “graft” placed into or near infected bone cavities around a knee replacement (TKA) to help new bone grow. You may be considered if you have an infected knee implant area and can safely take part in follow-up visits and treatment.
Los Angeles, CaliforniaAges 22 years+ - NCT07653295Recruiting
Study of Tıpmed revision hip replacement safety
This study follows patients who already had a revision hip replacement using the Tıpmed system. Researchers want to confirm the implant is safe and works well over time.
BalıkesirAges 18 years+ - NCT07284563RecruitingPhase 2
Ultra-low dose bone scan imaging study
This trial tests a much smaller amount of radiation during a PET scan to see if it can still show bone issues clearly. You might join if you need a bone scan and want to try a lower radiation approach.
Englewood, New JerseyAges 18–120 - NCT07406893Recruiting
Reducing Infection Risk in Shoulder Replacement Surgery
This trial tests whether a special gel (Prontosan) applied during shoulder replacement surgery can reduce the risk of infection. It is for men having their first shoulder replacement.
St Louis, MissouriAges 18 years+ - NCT06464770Recruiting
Improving infection prevention before shoulder surgery
This study compares different ways to clean the skin before shoulder surgery to prevent infection. It might help if you are going to have shoulder surgery and want safer, more effective infection prevention.
Seattle, WashingtonAges 18–89 - NCT05284318Recruiting
Antibiotic plans and outcomes after two-stage joint revision
This study looks at how antibiotic treatment (especially the course length and approach) relates to infection control and results after a two-step surgery for joint infections. If you’ve had a spacer placed, finished at least 6 weeks of antibiotics, and then had the second surgery, the research team may want to follow your outcomes over time.
Fuzhou, FujianAges 18 years+ - NCT04496024Recruiting
How ofloxacin levels may affect older adults with bone infections
This study looks at whether blood levels of the antibiotic ofloxacin in people over 65 are linked to side effects, in older adults hospitalized for bone and joint infections. It may help doctors choose safer doses, especially when switching from IV treatment to pills.
AmiensAges 65 years+ - NCT03713528Enrolling by invitationPhase 4
Antibiotic placed in bone to help save an infected knee implant
This trial tests whether putting antibiotics directly inside the bone during surgery can improve outcomes for an infected knee prosthesis when the implant is being kept. It may help more people avoid needing full implant removal and replacement.
San Francisco, CaliforniaAges 18 years+ - NCT06268795Recruiting
Comparing biopsy vs. aspiration for shoulder/elbow revision surgery
This study compares two methods—biopsy (taking a small tissue sample) and aspiration (drawing fluid)—to see which one better detects infection in people having repeat shoulder or elbow replacement surgery. The results will help doctors choose the best test for future patients.
Wigan, LancashireAges 18 years+ - NCT06737809Recruiting
Silver-coated hip revision for infection
This trial tests a new silver-coated hip implant for people who need a revision due to a chronic infection around the joint. It may help control the infection while replacing the implant.
BerlinAges 18 years+ - NCT06889701RecruitingPhase 1/Phase 2
Testing TNP-2092 for knee infection after joint replacement
This trial tests a new antibiotic, TNP-2092, given as a shot directly into the knee joint for people with a persistent infection after knee replacement. It is for those whose infection is caused by certain bacteria and who are willing to stay in the hospital for 2 weeks.
Ürümqi, XinjiangAges 18 years+ - NCT07324954RecruitingPhase 1
Methylene blue for knee replacement surgery
This study tests if using a blue dye called methylene blue during knee replacement surgery can help doctors see and clean out infections better. It may help people having a first-time knee replacement or those with an infected knee replacement.
Miami, FloridaAges 18 years+ - NCT07313215Recruiting
Study of rifampin combo therapy for staph joint infections
This study tests whether adding rifampin to standard antibiotics works better for people with a staph infection in a joint replacement. It aims to find a more effective treatment for this type of infection.
Fuzhou, FujianAges 18–80 - NCT05642013Recruiting
Short interval exchange surgery for infected hip or knee implants
This study compares how to replace an infected hip or knee implant using a two-step surgery with a shorter waiting time. It aims to reduce the time between surgeries while still safely treating the infection.
MontpellierAges 18 years+ - NCT04297592Enrolling by invitationPhase 4
Antibiotics to prevent infection after hip or knee replacement
This trial studies whether giving antibiotics before and/or after surgery can lower the chance of a serious joint infection after elective hip or knee replacement. It’s aimed at people at higher risk for infection.
Iowa City, IowaAges 18–99 - NCT05679232Recruiting
Hydrogel coating to lower infection after hip replacement surgery
This trial studies whether a special hydrogel coating on a hip implant can reduce infections after hip revision surgery. If it works, it could help you heal with fewer post-surgery infection problems.
ViennaAges 18 years+
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Common questions
- Are there clinical trials for joint infection?
- Yes. Clin2 currently lists 46 recruiting joint infection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a joint infection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a joint infection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.