Clinical trials
Knee Injuries clinical trials
Below are recruiting knee injuries clinical trials, each written for real people, not researchers. We’re tracking 70 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05073276Recruiting
Controlled weight-bearing after PCL or MCL knee ligament repair
This trial tests a specific, step-by-step approach to how much weight you put on your healing knee after surgery for certain ligament injuries (like PCL and/or MCL, and some combined cases). It may help you heal safely and recover function without putting too much strain on the repair.
Edina, MinnesotaAges 14–59 - NCT04875052Recruiting
Study vibration after ACL injury and future arthritis risk
This study looks at whether using vibration after an ACL injury helps predict or reduce the risk of developing post-traumatic osteoarthritis (wear-and-tear arthritis) later. It may help researchers learn which patients are more likely to develop arthritis after ACL reconstruction.
Chapel Hill, North CarolinaAges 16–35 - NCT07134244Recruiting
Predicting cartilage damage and pain after knee injury or early arthritis
This study uses computer models and MRI scans to predict how knee cartilage and pain may change over time in people with early osteoarthritis or a recent ACL tear. It aims to find better ways to manage these conditions and prevent long-term damage.
Aalborg, North DenmarkAges 18–70 - NCT07499973Recruiting
Core muscle strength and knee stability for injury prevention
This study looks at how your core (abdominal muscles) affects knee stability. It will test a training program to see if it helps prevent injuries. You will be randomly assigned to either the training group or a control group for 8 weeks.
Villaviciosa de Odón, MadridAges 18–35 - NCT07356674Recruiting
Surgery for Meniscus Tear with Mild Bow Legs
This trial tests a new surgical approach for a specific type of meniscus tear (the cartilage that cushions the knee) in people who have a mild bow-legged (varus) knee. It combines a small bone cut near the knee with arthroscopic repair to fix the tear.
Shenzhen, GuangdongAges 35–75 - NCT06024850Recruiting
Predicting good results after knee ligament repair
This study looks at people who had surgery to repair several torn knee ligaments. It aims to find out what factors lead to better results after the surgery.
Saint-EtienneAges 18 years+ - NCT06195423Recruiting
Stopping knee arthritis after an ACL tear
This study tests a home exercise program to prevent knee arthritis after an ACL tear. If you had ACL surgery 9 to 36 months ago and still have some knee symptoms, this program may help protect your knee in the long run.
Vancouver, British ColumbiaAges 16–35 - NCT07013019Recruiting
Normal knee rotation in athletes
This study measures normal knee rotation in athletes who play sports with pivoting movements. It helps doctors understand what healthy knee motion looks like, so they can better diagnose injuries.
Toulon, VarAges 15 years+ - NCT06194838Recruiting
Mechanical vs. powered knee for above-knee amputees
This study compares a non-powered (mechanical) knee to a powered (battery-assisted) knee for people with above-knee amputations who walk at a moderate level (K2). It will help find out which knee type works better for your daily activities and mobility.
Austin, TexasAges 18 years+ - NCT06635655Recruiting
Testing a new prosthetic knee for mental ease
This study tests whether a new prosthetic knee system helps reduce mental effort while walking for people with above-knee amputations. If you use a prosthetic leg and are comfortable with a smartphone, you may be able to join.
Multiple LocationsAges 18–84 - NCT05073263Recruiting
Full versus partial weight bearing after FCL ligament repair
This study compares two rehab plans: doing full weight bearing versus partial weight bearing during the first 6 weeks after fibular collateral ligament (FCL) reconstruction. It may help figure out which approach is safer and better for healing and recovery.
Edina, MinnesotaAges 14–59 - NCT05124652Recruiting
Testing a prosthetic socket that adjusts automatically
This trial is testing a prosthetic socket that can automatically adjust to help fit better and feel more comfortable. It may help people with below-knee (transtibial) amputations who currently struggle with socket fit or comfort.
Seattle, WashingtonAges 18 years+ - NCT05323474Recruiting
Rehab program after ACL surgery to return to competitive sport
This study tests an “optimized” rehabilitation plan after ACL reconstruction to help people safely return to competitive sports. It’s for people who had an ACL surgery and still want to play sports that involve cutting, pivoting, or contact.
Challes-les-EauxAges 18–25 - NCT05425810Recruiting
Smart tool to help check prosthetic socket fit
This study tests an easy-to-use smart system (called ENABLE) that helps assess whether a prosthetic socket fits your leg well. It may help improve comfort and reduce skin problems by making sure the socket fit is assessed in a consistent, affordable way.
Raleigh, North CarolinaAges 18–99 - NCT05655156Recruiting
Study of a pig-tissue implant for serious knee ligament injuries
This trial studies an implant made from pig tissue for people with multiple injured knee ligaments. It aims to see how well the implant works and whether people can safely follow the required rehabilitation plan.
Stoke-on-TrentAges 18 years+ - NCT05818410Recruiting
Brain and tech training after below-knee leg loss
This study looks at how your brain works with assistive technology after losing a leg below the knee. It may help researchers improve how prosthetic devices feel and function by measuring brain and movement signals during training.
BrusselsAges 18–65 - NCT06073106Recruiting
Frailty prevention study for older Asian adults
This trial tests a program to prevent frailty in people aged 50 and older of Asian descent who have recently been diagnosed with a stroke, traumatic brain injury, knee osteoarthritis, or breast cancer. The goal is to help you stay strong and healthy as you recover.
Singapore, SingaporeAges 50 years+ - NCT06507241Recruiting
Knee meniscus root tear repair using ligament suture
This trial tests a surgical technique to fix a certain type of meniscus tear (called a root tear) by stitching it to the knee's posterior cruciate ligament. The goal is to see if this approach helps patients recover better.
BolognaAges 18–50 - NCT06505525Recruiting
ACL reconstruction: adding extra support vs standard surgery
This trial compares two surgical techniques for ACL reconstruction. The standard method repairs the ACL inside the knee joint, while the new method also adds extra support outside the joint. The study aims to see which approach gives better stability and recovery for people with specific risk factors, like being a young athlete or having a chronic ACL tear.
São Paulo, São PauloAges 14–40 - NCT06541756Recruiting
Fibrin clot repair for torn knee cartilage
This trial tests whether adding a fibrin clot to standard meniscus repair helps heal a torn knee cartilage better. You'd get surgery, then an MRI one year later to check healing.
AnkaraAges 18–50 - NCT06571240Recruiting
Turkish Activity Score Tool for ACL Surgery Patients
This study checks if a new Turkish version of an activity score (Tegner) is valid and reliable for people having ACL surgery. If you are having your first ACL repair and speak Turkish, you may be able to take part.
AnkaraAges 18 years+ - NCT07075198Recruiting
Testing the Caesar running foot for people with below-knee amputations
This trial tests a new running foot called Caesar for people with below-knee amputations who want to run but don't have a running blade yet. You'll try the foot at home and give feedback on how it works.
Austin, TexasAges 18 years+ - NCT06452186Recruiting
Study of a new leg prosthetic controller for improved balance
This study tests a new prosthetic leg controller that helps people with below-knee amputations walk more steadily and with better balance. You may be eligible if you have used a prosthetic leg for at least a year and are comfortable walking in the community.
Raleigh, North CarolinaAges 18–99 - NCT02918734Recruiting
ACL surgery: compare two ways to secure the tendon graft
This study looks at two surgical methods to attach the tendon graft during ACL reconstruction, using either an Endobutton or metal interference screws. It may help patients by improving how securely the graft is fixed and how well recovery goes.
TrondheimAges 18–55
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Common questions
- Are there clinical trials for knee injuries?
- Yes. Clin2 currently lists 70 recruiting knee injuries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a knee injuries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a knee injuries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.