Clinical trials
Left Ventricular Dysfunction clinical trials
Below are recruiting left ventricular dysfunction clinical trials, each written for real people, not researchers. We’re tracking 63 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07666698RecruitingPhase 1/Phase 2
Metformin to improve heart function after LVAD implant
This trial tests if metformin, a medicine commonly used for diabetes, can help improve heart function in people who have a mechanical heart pump (LVAD). You may be able to join if you are between 18 and 75, have a continuous-flow LVAD, and have a condition called insulin resistance (where your body doesn't use insulin well) but your blood sugar levels are well-controlled.
Nanjing, JiangsuAges 18–75 - NCT07560085Recruiting
Heart Pump Device to Help After Heart Surgery Complications
This trial tests a new heart-assist device designed to help patients whose hearts are too weak to pump blood on their own after heart surgery. The device is placed through a catheter (thin tube) and aims to improve blood flow and survival in people who don't respond to standard medications.
Fuzhou, FujianAges 18–80 - NCT06831825RecruitingPhase 1
Gene therapy for heart failure recovery trial
This trial tests a gene therapy injected into the heart to help it recover after a previous heart attack. It may be an option for people with stable heart failure who are not eligible for standard procedures like stents or bypass surgery.
Houston, TexasAges 18–79 - NCT07103655Enrolling by invitationPhase 4
Mavacamten for mid-to-apical obstruction in HCM
This trial tests if mavacamten can help people with hypertrophic cardiomyopathy (HCM) who have obstruction in the middle or tip of the heart (not the usual outflow tract). You may join if you have symptoms like chest pain or shortness of breath and a pressure gradient above 30 mmHg in these areas.
Hangzhou, ZhejiangAges 18–75 - NCT07094919Recruiting
Corheart 6 heart pump long-term study
This study follows people who have already received the Corheart 6 heart pump to see how well it works over time. You may qualify if you have severe heart failure that doesn't improve with standard treatments and you got the pump after October 1, 2021.
Shenzhen, GuangdongAges 18 years+ - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Phoenix, ArizonaAges 18 years+ - NCT06310031Recruiting
Testing BrioVAD heart pump for severe heart failure
This trial tests a new left-ventricular assist device (LVAD) called BrioVAD for people with advanced heart failure who are not getting enough benefit from medicines. If you qualify, the device is implanted to help your heart pump blood.
Birmingham, AlabamaAges 18–100 - NCT06053580RecruitingPhase 2
Valsartan for pulmonary hypertension: protection study
This trial tests whether a blood pressure medicine called valsartan can help protect the lungs and heart in people with a specific type of pulmonary hypertension (Group 1 PAH). If you have PAH and are stable enough to walk 50 meters, you may be able to join.
Seattle, WashingtonAges 18–80 - NCT05876000Recruiting
Heart pump study for very severe heart failure
This trial tests a left ventricular assist system (a mechanical heart pump for the left side of the heart) in people with very severe heart failure. It may help people who are too sick or not improving despite best available medical treatment.
GrazAges 18–75 - NCT05450328RecruitingPhase 2
Breathing medicine to help heart-lung machine separation after surgery
This Phase 2 trial tests whether inhaled medicines (milrinone and epoprostenol) can make it easier to separate from the heart-lung machine during cardiac surgery. It may help reduce the risk of a difficult transition off the machine for the right patients.
Montreal, QuebecAges 18 years+ - NCT04768322Recruiting
LVAD versus standard heart failure medicines in advanced patients
This trial compares an LVAD device (a pump placed in the chest) plus medicines versus medicines alone for people with advanced, end-stage heart failure. It aims to see which approach works better to help patients live and stay out of the hospital.
BesançonAges 18 years+ - NCT06707662Recruiting
Pacing methods to protect heart function
This trial tests two pacing approaches to see which one better prevents weakening of the heart's main pumping chamber. It's for people who need a pacemaker for a slow heart rhythm and are expected to rely on it heavily.
BarcelonaAges 18 years+ - NCT07576894Recruiting
How the Heart Responds to Exercise in COPD Patients
This study looks at how the right side of your heart responds when you exercise, in people with COPD (a chronic lung condition). The goal is to understand this response better and potentially improve treatments.
Aurora, ColoradoAges 40 years+ - NCT06580717RecruitingPhase 4
Testing empagliflozin for heart stiffness in hypertrophic cardiomyopathy
This study tests whether a diabetes drug (empagliflozin) can improve the heart's ability to relax and fill with blood in people with non-obstructive hypertrophic cardiomyopathy, a type of heart muscle thickening. You may be able to join if you have this condition and are not currently taking an SGLT2 inhibitor.
SeoulAges 19–80 - NCT07314008Recruiting
Comparing pacing methods for slow heartbeat with long AV delay
This trial tests two types of heart pacing to see which works better for people with a slow heartbeat from sinus node issues and a long delay between the upper and lower heart chambers (PR interval over 200 ms). The goal is to find the best way to pace the heart while keeping unnecessary pacing minimal.
Seoul, Songpa-guAges 18 years+
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Common questions
- Are there clinical trials for left ventricular dysfunction?
- Yes. Clin2 currently lists 63 recruiting left ventricular dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a left ventricular dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a left ventricular dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.