Clinical trials
Leg Ulcer clinical trials
Below are recruiting leg ulcer clinical trials, each written for real people, not researchers. We’re tracking 56 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06453187Enrolling by invitation
Testing wound dressings for diabetic and vein ulcers
This study tests whether special wound dressings (called CAMPs) can help heal diabetic foot ulcers and venous leg ulcers faster. If you have a hard-to-heal sore on your foot or leg, this trial may be an option.
Los Angeles, CaliforniaAges 18–80 - NCT04210089Recruiting
Soft cast bandage for diabetic foot ulcers
This study tests whether a “total contact” soft cast bandage helps people heal diabetic foot ulcers. You may be asked to get your leg wrapped and have regular follow-up visits so the ulcer can be checked closely.
Minneapolis, MinnesotaAges 18 years+ - NCT05303805RecruitingPhase 4
Sevoflurane gel for painful, slow-healing leg ulcers
This trial studies a topical (skin-applied) form of sevoflurane to help painful leg ulcers that are not healing on their own. If you have ongoing ulcer pain and can report it reliably, you may be considered for this treatment study.
PragueAges 18 years+ - NCT06153589Recruiting
Music therapy for leg ulcer pain relief
This trial tests whether listening to music during wound cleaning can reduce pain for people with leg ulcers caused by vein or artery problems. It aims to make the procedure more comfortable.
Fort-de-FranceAges 18 years+ - NCT06560502Recruiting
Testing new treatments for diabetic foot and leg ulcers
This trial tests whether adding a special treatment (cellular acellular and matrix-like products) to standard wound care helps diabetic foot ulcers and venous leg ulcers heal faster. It may be an option if you have a diabetes-related foot ulcer that hasn't healed with standard care.
Circleville, OhioAges 21 years+ - NCT06693570RecruitingPhase 4
Fish skin graft for hard-to-heal leg ulcers
This trial tests whether applying a special fish skin graft, along with standard compression therapy, helps heal leg ulcers caused by poor vein function (venous leg ulcers) that have not healed with standard care alone. If you have a nonhealing venous leg ulcer, this study may offer a new treatment option.
Monroeville, PennsylvaniaAges 18 years+ - NCT06697925Recruiting
Venous leg ulcer closure durability study
This trial checks how long the closure of a venous leg ulcer lasts after healing. It is only for people who already took part in an earlier study (THOR trial) and had their ulcer fully close within 12 weeks.
Monroeville, PennsylvaniaAges 18 years+ - NCT06707090RecruitingPhase 3
Tissue repair gel for venous leg ulcers
This trial tests a gel that helps heal leg ulcers caused by poor blood flow in the veins. It may help if you have a venous leg ulcer that has not healed on its own after at least 4 weeks.
Tucson, ArizonaAges 18 years+ - NCT06707103RecruitingPhase 3
Gel treatment for venous leg ulcers
This trial tests whether a special gel helps heal venous leg ulcers faster. It is for people with a diagnosed vein problem and a leg ulcer between 2 and 12 square centimeters that has been present for at least 4 weeks.
Jacksonville, FloridaAges 18 years+ - NCT06826339RecruitingPhase 4
Advanced wound treatments for diabetic foot and leg ulcers
This study compares several advanced wound treatments (called CAMPs) plus standard care to standard care alone for hard-to-heal diabetic foot ulcers and venous leg ulcers. It aims to see if the extra treatments help wounds close faster and prevent complications.
Monroeville, PennsylvaniaAges 21 years+ - NCT06899919Recruiting
Light compression wrap for mixed leg ulcers
This trial tests a light compression system for mixed leg ulcers, which are wounds on the lower leg that have both vein and artery problems. It may help you if you have this type of wound that is not too large or too old.
Paris, ParisAges 18 years+ - NCT07048054RecruitingPhase 1/Phase 2
Patch of fat cells for chronic leg ulcers
This trial tests a patch made from your own fat cells (called TrophiPatch) to see if it helps heal chronic leg ulcers. It is for people with venous leg ulcers or diabetic foot ulcers that are not healing well with standard care.
GenevaAges 18 years+ - NCT07089602RecruitingPhase 4
Placental membrane for diabetic and venous leg ulcers
This trial tests if a placental membrane product, when added to standard wound care, helps heal diabetic foot ulcers and venous leg ulcers faster than standard care alone.
Philidelphia, PennsylvaniaAges 18 years+ - NCT07364630RecruitingPhase 4
Placental membrane trial for diabetic and venous leg ulcers
This study tests whether a special wound dressing made from human placental membrane can help heal diabetic foot ulcers or venous leg ulcers that did not close with standard care. It is for people who were in the BIOCAMP trial and whose ulcer remained open after 12 weeks of standard treatment.
Philidelphia, PennsylvaniaAges 18 years+ - NCT02280733Recruiting
Chronic wound registry for real-world care documentation
This study is a real-world registry that collects information about chronic wounds and ulcers as they’re treated in everyday settings. It may help improve how care is tracked and supported, even if you don’t get a new medicine from the study.
The Woodlands, TexasAges Any age - NCT02047084Enrolling by invitation
Test graft skin vs Apligraf for venous leg ulcers
This trial compares a new type of donated skin graft (human allograft) to Apligraf for treating venous leg ulcers that have not healed with standard care. It aims to see which option heals ulcers better and more safely.
Greenville, South CarolinaAges 21–90 - NCT07294521RecruitingEarly Phase 1
Platelet-rich fibrin gel for chronic leg ulcers
This trial tests if a gel made from your own blood (platelet-rich fibrin) can help heal chronic leg ulcers that are not infected. It may be a good option if you have a long-lasting leg ulcer without signs of infection.
Rawalpindi, Punjab ProvinceAges 35 years+ - NCT06754735RecruitingPhase 4
Oxygen therapy for chronic leg ulcers
This study tests a new device that delivers oxygen to the wound area (topical wound oxygen therapy) to help heal chronic leg ulcers caused by vein disease. It may help people who have not seen enough healing with compression therapy alone.
New York, New YorkAges 18 years+ - NCT07061613Recruiting
Study of NeoThelium FT for venous leg ulcers
This trial tests a new wound dressing called NeoThelium FT for healing venous leg ulcers. It looks at how safe and effective it is.
Metairie, LouisianaAges 18 years+ - NCT07211243Recruiting
Comparing two dressings for infected leg ulcers
This trial tests if a new version of a special dressing (Suprasorb X+PHMB Pro) works better than the current version for treating infected venous leg ulcers. It may help people with mildly to moderately draining wounds that are infected.
BialystokAges 18 years+ - NCT07335861Recruiting
Hyalomatrix for healing venous leg ulcers
This trial tests a special gel-like dressing (Hyalomatrix) to see if it helps heal leg ulcers caused by poor blood flow in the veins. It may be a good option if you have a chronic venous leg ulcer that hasn't healed much despite standard care.
Alexandria, LouisianaAges 18 years+ - NCT07510412Recruiting
NuShield plus standard care for venous leg ulcers
This trial tests a new wound covering called NuShield, used with standard care, to help heal leg ulcers caused by poor vein circulation. It may be an option if your ulcer hasn't healed after standard treatment.
Pickerington, OhioAges 18 years+ - NCT05608317Recruiting
Track healing of draining leg ulcers with a foam dressing
This study follows how a non-bordered foam dressing helps chronic leg ulcers that leak fluid (exuding). It mainly aims to see how the wound changes over time, and whether the dressing is comfortable and effective along with standard care.
San Francisco, CaliforniaAges 18 years+ - NCT05588583Recruiting
Tracking drainage from chronic leg or foot ulcers with a dressing
This study follows how much fluid (drainage) a chronic ulcer produces over time using a dressing called Mepilex Up. It may help clinicians better understand how this dressing manages “exuding” ulcers on the leg or foot.
Castro Valley, CaliforniaAges 18 years+
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Leg Ulcer trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for leg ulcer?
- Yes. Clin2 currently lists 56 recruiting leg ulcer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a leg ulcer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a leg ulcer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.