Clinical trials
Lidocaine clinical trials
Below are recruiting lidocaine clinical trials, each written for real people, not researchers. We’re tracking 133 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07706348RecruitingPhase 1/Phase 2
Pain relief with ondansetron and lidocaine after abdominal cancer surgery
This trial tests if rinsing the belly with ondansetron (a nausea medicine) and lidocaine (a numbing medicine) during surgery can reduce pain afterward. It is for people having major lower abdominal cancer surgery who are otherwise healthy.
AsyutAges 20–70 - NCT03756961Recruiting
Opioid-free care plan for people having weight-loss surgery
This trial studies whether an opioid-free or opioid-sparing care pathway can improve comfort and outcomes for adults undergoing laparoscopic weight-loss surgery. It may help people avoid side effects from opioid pain medicines while still managing pain safely.
Lindesberg, Region ÖrebroAges 18 years+ - NCT03924791Recruiting
Epidural injection trial for acute sciatica pain
This study tests whether a specific back/nerve pain injection (an epidural injection) can help people with acute sciatica. You may qualify if your sciatica started a few weeks ago and your leg pain is still quite severe.
HaarlemAges 18 years+ - NCT04397484RecruitingPhase 4
Compare two local anesthetics after foot nerve blocks
This study tests whether lidocaine or levobupivacaine works better for how a nerve block behaves after foot surgery. It may help doctors choose the anesthetic that provides more reliable pain control after surgery.
Shatin, New TerritoriesAges 18–75 - NCT05543694RecruitingPhase 4
Testing epidural pain relief for labor
This study is testing how well a combination of two medicines (bupivacaine and lidocaine) works for epidural pain relief during early labor. The goal is to find the best dose to help manage labor pain.
Boston, MassachusettsAges 18–50 - NCT06146842RecruitingPhase 4
Pain relief study for labor epidurals
This study tests two different epidural techniques to find the best dose of pain medicine for labor. It aims to improve comfort during childbirth.
Boston, MassachusettsAges Any age - NCT04992572RecruitingEarly Phase 1
Comparing two types of anesthesia for back decompression surgery
This early study compares two anesthesia approaches during lumbar decompression (back surgery to relieve pressure on nerves). It may help improve comfort and safety during surgery, but whether you personally benefit is not yet known.
Redwood City, CaliforniaAges 40–95 - NCT05501262Recruiting
Cryoablation vs steroid injection for Morton’s neuroma pain
This trial compares two ways to treat Morton’s neuroma pain: freezing treatment (cryoablation) versus steroid plus lidocaine injections. It may help people who didn’t improve after trying basic shoe inserts or padding, by seeing which approach works better for symptoms.
Portland, OregonAges 18–105 - NCT06045936RecruitingPhase 4
Nerve block for phantom limb pain
This study tests whether a nerve block in the remaining part of your leg can help reduce phantom limb pain or pain in the residual limb. It is for people who have had an amputation more than a year ago and still have pain despite trying other treatments.
Mankato, MinnesotaAges 18 years+ - NCT06189781RecruitingPhase 4
Pain shot vs epidural for hip surgery in kids with cerebral palsy
This study compares a pain injection to epidural anesthesia for children with cerebral palsy having hip surgery. The goal is to see which method provides better pain control during and after the procedure.
Los Angeles, CaliforniaAges Up to 18 years - NCT06254534Recruiting
Medications for eye pressure during breathing tube placement
This study tests how four different medications affect pressure inside the skull during the placement of a breathing tube for surgery. The medications are lidocaine, dexmedetomidine, esmolol, and magnesium—all commonly used to calm the body's response to intubation.
IstanbulAges 18–80 - NCT06446960RecruitingPhase 3
Nerve blocks for stroke-related central pain
This study tests whether numbing the nerves in your painful arm or leg (with a nerve block) can help reduce central pain after a stroke. It aims to find out how the nerves outside your brain and spinal cord may be involved.
Boulogne-BillancourtAges 18 years+ - NCT06452147Recruiting
Anesthesia and brain health after hip surgery in older adults
This trial is testing different types of anesthesia to see how they affect brain function (memory, thinking) after hip fracture surgery in older adults. It aims to find the safest approach for elderly patients.
Wenzhou, ZhejiangAges 65 years+ - NCT06564987RecruitingPhase 1
Risk of nerve damage from numbing shots for dental work
This study looks at whether a common numbing shot for dental procedures can cause nerve damage. It may help dentists choose safer ways to numb your teeth.
Akron, OhioAges 18–55 - NCT06582810Recruiting
Lidocaine for headaches after brain bleed
This study tests whether a lidocaine infusion (given through an IV) can safely reduce severe headaches after a subarachnoid hemorrhage (a type of brain bleed). You may qualify if you had a spontaneous bleed and can communicate your pain level.
Wichita, KansasAges 18 years+ - NCT06631976Recruiting
Non-surgical treatment for partial rotator cuff tear
This trial tests a conservative (non-surgical) approach for people with a small tear in the supraspinatus tendon (a rotator cuff muscle) that is causing shoulder pain and sleep problems. It aims to see if avoiding surgery can help improve symptoms and sleep quality.
Lodz, Łódź VoivodeshipAges 40–75 - NCT06776094Recruiting
Exercise and insulin sensitivity study in healthy men
This trial looks at how physical activity affects how your body responds to insulin in healthy men aged 22-35. If you are a non-smoking man with a BMI between 28 and 35 and a certain fitness level, you may be eligible.
CopenhagenAges 22–35 - NCT06793527Recruiting
Pain relief methods for laparoscopic bariatric surgery
This trial compares three different pain relief methods during weight-loss surgery: a nerve block, a lidocaine drip, and a targeted injection near the celiac plexus. The goal is to find which approach works best with fewer side effects.
Krakow, Lesser Poland VoivodeshipAges 18–75 - NCT06804434Recruiting
Pain monitor during stomach or liver cancer surgery
This trial tests a device that monitors your pain level during surgery using a special index called the Nociception Level Index. It may help doctors manage your pain better without using too much medicine.
Cluj-Napoca, ClujAges 18 years+ - NCT06872437RecruitingPhase 3
Study of pudendal nerve injections for nerve pain treatment
This trial tests if a numbing injection into the pudendal nerve can reduce pain after one month. It's for people with pudendal neuralgia that hasn't improved with medication.
ParisAges 18 years+ - NCT06999057RecruitingEarly Phase 1
Knee injury study for healthy active adults
This trial studies how your thigh muscle adapts after a simulated knee injury. It uses mild electrical stimulation and a small needle to measure muscle signals, and may help improve recovery after knee injuries.
Orlando, FloridaAges 18–30 - NCT07026513Recruiting
Aminaphtone and lidocaine spray for hemorrhoids
This trial tests a medication called aminaphtone taken by mouth, combined with a lidocaine spray, to treat painful internal hemorrhoids. It may help reduce symptoms without surgery.
TrevisoAges 18–85 - NCT07045870Recruiting
Pain relief methods after thyroid surgery
This study compares different ways to manage pain after thyroid removal surgery. It aims to find which method works best for recovery.
SohagAges 18–75 - NCT07116408RecruitingPhase 4
Numbing spray for headaches after brain bleed
This study tests if a numbing spray applied inside the nose can help reduce headaches in people who have had a brain bleed from a ruptured aneurysm. The treatment targets a nerve cluster linked to headache pain.
Dayton, OhioAges 18 years+
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Common questions
- Are there clinical trials for lidocaine?
- Yes. Clin2 currently lists 133 recruiting lidocaine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lidocaine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lidocaine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.