Clinical trials
Liver Transplantation clinical trials
Below are recruiting liver transplantation clinical trials, each written for real people, not researchers. We’re tracking 200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05146336Recruiting
CytoSorb registry for critically ill patients needing blood treatment
This registry collects information about critically ill patients who receive the CytoSorb 300 mL blood treatment. It may help doctors better understand when the treatment works best and when it should not be used.
KlagenfurtAges Any age - NCT05428267Recruiting
Sexual function study for people with cirrhosis
This study looks at sexual dysfunction in people who have cirrhosis (scarring of the liver). It may help researchers understand causes and better care for sexual problems in this condition.
ParisAges 18 years+ - NCT07335601RecruitingPhase 2
Resmetirom for liver health after transplant in MASH patients
This trial tests an experimental drug, resmetirom, to see if it can help people who have had a liver transplant for MASH and now have fatty buildup in their new liver. It may also help people who had a transplant for other reasons but developed fatty liver afterward. The study focuses on those with moderate to advanced liver scarring (F2-F3).
La Jolla, CaliforniaAges 18–75 - NCT06718517Recruiting
Testing drug levels to improve antibiotic therapy in liver transplant patients
This trial checks if monitoring antibiotic levels in the blood can help doctors give the right dose to liver transplant patients with serious bacterial infections. The goal is to make the treatment work better.
BolognaAges 18 years+ - NCT07315204Recruiting
Liver viability test during machine perfusion
This trial tests a new way to check if a donated liver is healthy while it is kept on a machine that keeps it alive before transplant. Doctors measure a substance called FMN in the fluid that flows through the liver and in bile. This could help them know how well the liver might work after transplant.
Cleveland, OhioAges 18 years+ - NCT06513780Recruiting
Liver transplant and portal vein blood clot study
This study looks at how blood clots in the portal vein (the main vein to your liver) affect recovery and outcomes after a liver transplant. If you've had a liver transplant, your data may help doctors understand this better.
BeijingAges 18 years+ - NCT06703008Recruiting
Monitoring blood flow during liver transplant surgery
This study is testing a way to closely monitor blood flow and pressure during liver transplant surgery to help improve safety and outcomes. It may help patients undergoing a liver transplant.
Bologna, Emilia-RomagnaAges 18 years+ - NCT07059494RecruitingPhase 4
Combination therapy for liver cancer before transplant
This trial tests a combination of two drugs (atezolizumab and bevacizumab) plus a targeted radiation treatment (Y-90 radioembolization) for people with liver cancer who are waiting for a liver transplant. The goal is to see if this treatment can help control the cancer and improve transplant outcomes.
New York, New YorkAges 18 years+ - NCT03845205Recruiting
Liver transplant timing study for alcohol-related liver disease
This study compares early versus standard liver transplant timing for people whose liver illness was caused by alcohol use. It looks at treatment outcomes to see which approach helps patients do better.
Baltimore, MarylandAges 18 years+ - NCT04838171Recruiting
Study of White Blood Cells in Donors and Patients
This study looks at white blood cells (the body’s immune cells) to learn more about how they behave in health and/or illness. Participation may help researchers understand immune-related changes and support future treatments.
LondonAges Any age - NCT05185505RecruitingPhase 4
Atezolizumab and bevacizumab before liver transplant for liver cancer
This trial tests giving atezolizumab plus bevacizumab before liver transplant in people with hepatocellular carcinoma (HCC) that is too advanced to be listed within the “Milan criteria,” but still transplant-eligible. The goal is to control the cancer outside the transplant period and improve transplant outcomes.
Houston, TexasAges 18 years+ - NCT05327478Recruiting
Compare treatments for controlled donation after circulatory death
This trial compares different care approaches for adult donors in a specific type of controlled donation after the heart stops. It aims to find which approach best supports organ/tissue use after donation.
Rotterdam, South HollandAges 50–75 - NCT05424003RecruitingPhase 2
Semaglutide to prevent weight gain after liver transplant
This trial tests semaglutide (a diabetes/weight-loss medicine) to help prevent weight gain after liver transplant. It is also looking at blood sugar and safety while you continue your transplant medicines.
Richmond, VirginiaAges 18–75 - NCT06218420RecruitingPhase 2
Radiation to bridge to liver transplant
This study tests whether a precise type of radiation (called stereotactic body radiotherapy or SBRT) can be used as a 'bridge' to keep your liver cancer from growing while you wait for a liver transplant. It may help more people stay healthy enough to receive a transplant.
ParisAges 18 years+ - NCT06290154Recruiting
Heart health after liver transplant study
This study looks at factors that affect heart health after a liver transplant. It may help doctors better predict and manage heart problems in people with end-stage liver disease who are getting a new liver.
Guangzhou, GuangdongAges 18 years+ - NCT06371924Recruiting
Machine perfusion for livers from donation after circulatory death
This study tests a new way to preserve donated livers (called machine perfusion) after they are recovered from donors who died from circulatory causes. It aims to see if this method helps the liver work better before transplant.
BirminghamAges 18 years+ - NCT06544863Recruiting
Better support for cirrhosis and liver transplant patients
This study tests a new care support program for people with cirrhosis or who have had a liver transplant. It aims to improve how patients are followed and helped at the hospital.
ParisAges 18 years+ - NCT06717919RecruitingPhase 4
Testing HOPE treatment to prevent liver cancer return after transplant
This study tests a special way of preserving donated livers, called HOPE, to see if it lowers the chance of liver cancer coming back after a liver transplant. If you have liver cancer and are waiting for a transplant, this trial might be an option for you.
New York, New YorkAges 18 years+ - NCT06862934Recruiting
Liver transplant for bile duct cancer that can't be removed
This study tests if a liver transplant can help people with a type of bile duct cancer (intrahepatic cholangiocarcinoma) that cannot be surgically removed. It is for patients whose cancer has been stable for at least 6 months after initial treatments.
Milan, MilanAges 18–70 - NCT06986486Recruiting
Liver transplant for perihilar bile duct cancer
This trial tests whether a liver transplant can help people with a specific type of bile duct cancer (perihilar) that cannot be removed with surgery. It aims to offer a potential cure for those whose tumor is small and hasn't spread.
Milan, MichiganAges 18–70 - NCT07077356RecruitingPhase 1
mRNA vaccine for liver cancer patients awaiting transplant
This trial tests an mRNA vaccine for people with liver cancer who are waiting for a liver transplant. The vaccine is given to help control the cancer while they wait.
ChengduAges 18 years+ - NCT02863250Recruiting
Blood transfusion registry for people needing frequent transfusions
This registry collects information from adults who receive frequent red blood cell transfusions. It may help clinicians understand transfusion needs and improve future care.
Melbourne, VictoriaAges 18 years+ - NCT05195944Enrolling by invitationPhase 4
Semaglutide versus sitagliptin after liver transplant for diabetes
This trial compares two diabetes medicines—semaglutide and sitagliptin—in people who have had a liver transplant and have type 2 diabetes (or diabetes after transplant). It’s looking to see which medicine works better and is safe for blood sugar control in the transplant setting.
Toronto, OntarioAges 18 years+ - NCT05548452RecruitingPhase 1/Phase 2
Microbiota transplant for advanced liver disease from alcohol
This trial tests whether giving a healthy mix of gut bacteria (an intestinal microbiota transplant) can improve outcomes in people with advanced liver disease caused by ongoing alcohol use. It may help rebalance the gut and support liver health, but participation depends on strict safety and diagnosis criteria.
Richmond, VirginiaAges 18 years+
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Common questions
- Are there clinical trials for liver transplantation?
- Yes. Clin2 currently lists 200 recruiting liver transplantation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver transplantation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver transplantation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.