Clinical trials
Long COVID-19 Syndrome clinical trials
Below are recruiting long covid-19 syndrome clinical trials, each written for real people, not researchers. We’re tracking 46 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06156176Recruiting
Exercise for COVID-19 fatigue: a feasibility study
This study tests whether a personalized exercise program can help reduce fatigue after a COVID-19 infection. You'll work with a coach over video calls to see if gentle activity can improve your energy levels.
London, OntarioAges 18 years+ - NCT06631287RecruitingPhase 3
Testing baricitinib for persistent long COVID symptoms
This trial tests whether the anti-inflammatory drug baricitinib can improve persistent long COVID symptoms like brain fog, fatigue, and shortness of breath. You may qualify if you had COVID-19 at least 6 months ago and still have bothersome symptoms that affect your daily life.
Tucson, ArizonaAges 18 years+ - NCT06528171Recruiting
Long COVID immunity and imaging study
This trial studies people who had COVID-19 to understand why some develop long-term symptoms while others recover fully. It aims to find links between the immune system and brain changes using imaging.
NiceAges 18 years+ - NCT06511063RecruitingPhase 2
Antiviral trial for treating long covid symptoms
This study tests whether antiviral drugs (Truvada and Selzentry) can help people with long COVID. You may qualify if you have had long COVID symptoms for at least 6 months, including fatigue and post-exertional malaise.
New York, New YorkAges 18 years+ - NCT06511050RecruitingPhase 1/Phase 2
Testing Lumbrokinase for Long COVID, Lyme, and Chronic Fatigue
This trial tests a supplement called Lumbrokinase (derived from earthworms) to see if it helps reduce symptoms in people with Long COVID, post-treatment Lyme disease syndrome, or ME/CFS. It may benefit those whose daily life is significantly affected by these conditions.
New York, New YorkAges 18 years+ - NCT06095297Recruiting
Cognitive rehab for brain fog from long COVID
This study tests a computer-based cognitive training program combined with a gentle nerve stimulation device to see if it can improve brain fog and daily functioning in people with long COVID. If you're struggling with thinking, memory, or concentration after COVID, this might help.
Birmingham, AlabamaAges 18 years+ - NCT05931497Recruiting
Sauna heat treatment for long COVID fatigue
This trial tests whether regular sauna sessions using infrared heat can reduce fatigue from long COVID. You may be eligible if you have ongoing fatigue after a confirmed or strongly suspected COVID infection and can safely spend time lying in a sauna.
Boston, MassachusettsAges 18–65 - NCT05977179Recruiting
Diet program for long-COVID fatigue and poor diet quality
This study tests whether improving diet quality can reduce fatigue and symptoms in people with long-COVID (post-acute COVID-19 syndrome). It may help if your diet quality is currently low and your fatigue is moderate to severe.
Baltimore, MarylandAges 50–94 - NCT05926505RecruitingPhase 2/Phase 3
Anakinra for lingering symptoms after COVID-19
This Phase 2/3 trial studies whether anakinra can improve ongoing (post-acute) COVID-19 symptoms lasting for more than two months. It mainly looks for better safety and symptom improvement in people with specific inflammation and lung-related findings.
JenaAges 18 years+ - NCT05787327RecruitingPhase 2
Chinese Herbal Medicine for COVID-19
This trial tests a combination of two traditional Chinese herbal formulas (Yinqiaosan and Maxingganshitang) to see if they can help people with mild to moderate COVID-19 recover faster. It's for adults who have had symptoms for no more than 3 days and have been diagnosed with a specific Chinese medicine pattern.
Hong KongAges 18–65 - NCT04978571Recruiting
Electrical nerve stimulation for long-lasting concussion symptoms
This study tests whether a device that delivers gentle electrical signals to nerves through the skin can help children and teens with concussion symptoms that have lasted at least 3 months. You may be asked to attend clinic visits for the nerve stimulation setup if you meet the safety and scheduling requirements.
Orange, CaliforniaAges 11–18 - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT05787379Recruiting
Care program for Veterans with long-lasting COVID symptoms
This trial tests a care approach for Veterans who have long-COVID—aiming to improve symptoms and follow-up care through participating VA clinicians. You may be included if you are a Veteran with long-COVID and can be seen by a participating clinician soon, unless you had severe COVID requiring ICU care.
East Orange, New JerseyAges Any age - NCT07359482RecruitingPhase 3
Fluvoxamine for fatigue after covid-19
This study tests the antidepressant fluvoxamine to see if it can reduce long-term fatigue in adults who developed severe tiredness after a covid-19 infection. You may join if your fatigue started or got worse after covid and has lasted at least 3 months.
Amsterdam-ZuidoostAges 18–70 - NCT06522750Recruiting
Periodic fasting for long COVID in adults
This study tests whether periodic fasting can help adults with long COVID. You may qualify if you are 18-64, have had COVID symptoms for at least 12 weeks, have a normal weight and low iron stores.
EttelbruckAges 18–64 - NCT05851859Recruiting
Breathing training for long COVID symptoms
This study tests whether a structured breathing control technique can improve symptoms of long COVID. It may help by training how you breathe, but you must meet specific health and medication criteria to join.
Saint-DenisAges 18 years+ - NCT06679140RecruitingPhase 3
Study of Ibuzatrelvir for COVID-19 in high-risk patients
This trial tests if a new medicine called ibuzatrelvir can help people with COVID-19 who have certain health risks avoid severe illness. It is for patients who cannot or choose not to take another COVID-19 pill called Paxlovid.
Huntsville, AlabamaAges 12 years+ - NCT07743580RecruitingPhase 3
Secutrelvir for covid-19 patients at high risk
This trial tests a new antiviral pill, secutrelvir, for people with mild to moderate covid-19 who are at higher risk of getting seriously ill. It aims to see if the drug can prevent hospitalization or severe disease.
Coral Gables, FloridaAges 12 years+ - NCT06932237Recruiting
Immune causes of long COVID brain symptoms in veterans
This study is for veterans who have long COVID with brain or nerve symptoms. It looks at how the immune system may be causing these ongoing symptoms.
Portland, OregonAges 18–80 - NCT06850350Recruiting
Long COVID and Thinking & Walking
This study looks at how Long COVID affects thinking and movement skills. If you had COVID-19 more than 3 months ago and could walk before you got sick, you may be able to help researchers understand these lasting symptoms.
Chicago, IllinoisAges 18 years+ - NCT04381936RecruitingPhase 3
Testing COVID-19 or pneumonia treatments in hospitalized patients
This trial tests different treatments for serious lung infections in people who are already in the hospital. It may help doctors learn which treatment works best for recovery and survival when pneumonia-like illness is suspected.
BrusselsAges birth+ - NCT00571389Recruiting
Collecting blood cells from people with cancer or COVID-19
This study collects blood cells using a special blood-draw procedure called leukapheresis (for some participants) and other samples. It aims to better understand cancer and immune-related cells, which may help researchers design or improve future treatments.
Huntersville, North CarolinaAges 5 years+
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Common questions
- Are there clinical trials for long covid-19 syndrome?
- Yes. Clin2 currently lists 46 recruiting long covid-19 syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a long covid-19 syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a long covid-19 syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.