Clinical trials
Lower Limb Injury clinical trials
Below are recruiting lower limb injury clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06293469Recruiting
Speeding up flap surgery for severe leg injuries
This trial tests whether performing flap surgery sooner after a severe leg injury below the knee leads to better outcomes. If you have an open fracture or dislocation that needs a flap, you may be able to join.
Sacramento, CaliforniaAges 18 years+ - NCT07739264Recruiting
Robotic hand training for arm weakness
This study tests a robotic hand training system called ZEPU-SG1PLUS to help improve arm and hand function in people with various conditions like stroke or injury. It aims to see if this device can help you move better and do daily activities more easily.
DhakaAges 18–60 - NCT05240014Recruiting
Powered leg braces to help people move more easily
This study tests modular powered leg braces (orthoses) to improve voluntary movement and walking ability in adult participants. It may help you learn whether the braces are safe and useful for your kind of mobility and daily movement.
Ann Arbor, MichiganAges 18–85 - NCT06473740RecruitingPhase 4
Gene therapy plus angioplasty for severe leg blockages
This study tests if adding gene therapy to a standard leg artery-opening procedure (angioplasty or stenting) helps people with severe leg pain or non-healing wounds due to blocked arteries. It may improve blood flow and save the leg from amputation.
Blagoveshchensk, Amur OblastAges 18 years+ - NCT06839885Recruiting
Water Therapy for Swelling in One Leg
This trial tests whether water-based therapy (hydrotherapy) can help reduce swelling in one leg caused by lymphedema. It's for people who have already tried standard lymphedema treatment.
IstanbulAges 18–75 - NCT07750808Recruiting
Walking rehabilitation with a robotic exoskeleton
This study tests a wearable robotic leg brace that helps people with leg weakness practice walking. It aims to see if using the robot improves strength and movement for people recovering from stroke, spinal cord injury, or joint replacement surgery.
DhakaAges 18–60 - NCT07817381Recruiting
Resistance and loading exercise for bone health
This trial tests a supervised exercise program with weights and jumping activities to improve bone health in males with one leg amputated below the knee. If you're already using a prosthetic leg and walking well, this study might help strengthen your bones.
LoughboroughAges 18–55 - NCT07768761Recruiting
Electrical stimulation exercise for lower limb paralysis
This trial tests whether a muscle exercise program using electrical stimulation can help people with paralysis in their legs. It may improve muscle strength, blood flow, or other health benefits.
Cleveland, OhioAges 18 years+ - NCT06667492Recruiting
Leg strength measurement in healthy kids
This study measures leg muscle strength in healthy children ages 5 to 16 to better understand normal development. If your child is developing typically and can follow instructions, they may be able to join.
Lamia, PhthiotisAges 5–16 - NCT07323147Enrolling by invitation
Robot-assisted walking therapy for hip fracture recovery
This study tests whether a robot suit can help older adults walk better after hip fracture surgery. If you are 65 or older and had surgery for a broken hip from a minor fall, you may be able to join.
Beijing, Beijing MunicipalityAges 65–100 - NCT06538974Recruiting
Long-term use of an exoskeleton for leg weakness
This trial tests a walking device called an exoskeleton to help people with leg weakness or movement problems. It's designed to see if using the exoskeleton regularly over time can help improve walking or mobility.
ParisAges 18 years+ - NCT07873424Recruiting
Recumbent cycling and electrical stimulation for leg rehab
This study tests whether combining recumbent cycling with electrical muscle stimulation can improve leg function. It may help people with leg weakness or injuries to recover strength and mobility.
Oro Verde, Entre Ríos ProvinceAges 18–60 - NCT07840781Recruiting
Building a performance model for amputee football players
This study aims to understand what makes amputee football players perform well, so it can help improve training and performance. If you play amputee football regularly, you may be able to join and contribute to this research.
AdanaAges Any age - NCT06543888Recruiting
Exoskeleton training for walking and daily tasks in older adults
This study tests whether a passive lower-limb exoskeleton can help older adults walk better and do daily activities more easily. You will wear the device during training sessions to see if it improves your movement and independence.
Taoyuan, GuishanAges 60 years+ - NCT07666828Recruiting
Electrical foot pad study for leg health in healthy adults
This trial tests three different electrical stimulation foot pad programs to see how they affect blood flow in the legs of healthy adults. It may help improve leg health by using mild electrical pulses on the feet.
Bracknell, BerkshireAges 18 years+ - NCT07641621Recruiting
Chiropractic Ankle Treatment and Jump Performance Study
This study tests whether chiropractic ankle manipulation improves how high and powerfully you can jump. Researchers will work with recreationally active adults to see if this treatment affects athletic performance.
Seneca Falls, New YorkAges 18–35 - NCT07578753Enrolling by invitation
Robot-assisted walking therapy for burn and fracture recovery
This study tests whether a robotic device that helps you walk can improve movement and function after you've had a severe burn and broken bone in your leg. The robot guides your leg through walking motions while you're healing, and researchers want to see if it helps you regain strength and independence faster.
SeoulAges 18–70 - NCT05859451Recruiting
Heated tobacco product study for surgically treated leg fractures
This study looks at whether a tobacco heating system (instead of cigarettes) affects how well a surgically repaired tibia or femur fracture heals. It mainly targets smokers with a certain smoking history who do not want to join free smoking-cessation seminars.
Tübingen, Baden-WurttembergAges 18 years+ - NCT07558317Recruiting
Resistance Exercise for Lower Leg Swelling
This study tests whether strength-training exercises can help reduce swelling in the lower leg caused by lymphedema. You'll wear compression garments as usual and add supervised resistance exercises to see if they improve your symptoms and quality of life.
HerlevAges 18 years+ - NCT07461701Recruiting
Comparing two squat intensities for strength in young women
This study compares two ways of doing bodyweight squats (stopping when you lose 15% vs 30% of your speed) to see which is better for building leg strength and endurance in young women who are not very active. It may help find a simple, safe way to improve fitness at home.
Lahore, Punjab ProvinceAges 18–25 - NCT07440615Recruiting
Leg muscle and heart performance in active adults
This study looks at how leg muscle size relates to heart and muscle performance in healthy men and women. It aims to understand normal differences between sexes.
EskişehirAges 18–30 - NCT07181434Recruiting
Virtual reality for pain relief during leg artery repair
This trial tests whether using a virtual reality headset during a leg artery repair procedure can reduce pain. If you have peripheral artery disease and are having a minimally invasive leg artery surgery under local anesthesia with sedation, you may be able to participate.
PoitiersAges 18 years+ - NCT07155967Enrolling by invitation
Blood flow restriction training for leg strength in older women
This trial tests whether a type of strength training that partly uses blood flow restriction can help older women build leg strength on one side, which may also benefit the other leg. It's for women who are generally healthy and have not had recent leg injuries or surgeries.
Presidente Prudente, São PauloAges 60 years+ - NCT07093229Enrolling by invitation
Gait analysis for knee arthritis in seniors
This trial studies how walking patterns change in people over 65 with long-term knee osteoarthritis. It aims to understand gait to improve treatment and rehabilitation plans.
CraiovaAges 65–80
Hear when a new Lower Limb Injury trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for lower limb injury?
- Yes. Clin2 currently lists 62 recruiting lower limb injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lower limb injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lower limb injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.