Clinical trials
Lumbar Stenosis clinical trials
Below are recruiting lumbar stenosis clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05029726RecruitingPhase 4
Numbing medicine during back surgery to reduce pain
This trial tests a regional anesthesia (numbing medicine given near nerves) during minimally invasive lumbar spine surgery. The goal is to see if it helps control pain around surgery and improves recovery comfort.
Chicago, IllinoisAges 18–80 - NCT05273879Recruiting
Testing whether one-level fusion is needed after lumbar decompression
This trial compares outcomes after decompression surgery for one affected area in the lower back, with and without adding spinal fusion. It may help patients avoid unnecessary extra surgery—or ensure fusion is used when it’s needed.
Moscow, MoscowAges 45–75 - NCT07026305Recruiting
Comparing surgical approaches for lumbar spinal stenosis
This study is comparing two surgical approaches for patients with lumbar spinal stenosis (narrowing of the lower spine). It aims to see if a less invasive surgery works as well as a more extensive procedure, which may help patients recover faster.
MadridAges 50 years+ - NCT07007663Recruiting
Directional preference in lumbar spinal stenosis
This study looks at whether people with lumbar spinal stenosis (a narrowing in the lower spine) have a 'directional preference'—a specific movement or position that eases their symptoms. If you have leg or buttock pain when walking, this trial may help find better ways to treat your condition.
Lake Success, New YorkAges 48 years+ - NCT06057428Recruiting
Activity levels in seniors having spine surgery
This study is tracking how active people are before and after surgery for lumbar spinal stenosis (a common cause of back and leg pain in older adults). It aims to see if activity monitoring can help improve recovery.
KøgeAges 65 years+ - NCT06075862Recruiting
Balance in patients with lumbar spinal stenosis
This study looks at balance problems in older adults with lumbar spinal stenosis, a condition that narrows the spinal canal and can cause pain or trouble walking. It may help doctors understand how surgery affects balance and daily life.
KøgeAges 65 years+ - NCT06719037Recruiting
Comparing two spine surgeries for lower back narrowing
This study compares two different surgical techniques – one using a small camera (endoscopic discectomy) and the other a traditional open approach (microdiscectomy) – to treat narrowing in the lower spine. It helps find which method may be better for relieving pain and improving function.
Jinan, ShandongAges 18–80 - NCT06750055Recruiting
Walking assessment after lumbar spinal stenosis surgery
This study looks at how well people walk after surgery for lumbar spinal stenosis. It may help you understand your recovery if you had surgery 6 weeks to 3 months ago.
DenizliAges 20–65 - NCT07026552Recruiting
Ligament study for lumbar spinal stenosis
This study looks at the ligament in your lower back to understand how lumbar spinal stenosis develops. It involves analyzing tissue samples and may help find better ways to treat this condition.
Rome, RMAges 50–85 - NCT07233798Recruiting
Dural pulsation in lumbar spinal stenosis
This study looks at a natural movement called dural pulsation (pulsing of the spinal sac) in people with lumbar spinal stenosis. It might help doctors understand the condition better and could lead to better treatments for your back or leg pain.
Pendik, IstanbulAges 18–85 - NCT07281625RecruitingEarly Phase 1
Comparing two types of back surgery for lumbar spinal stenosis
This study compares two surgical approaches for patients with lumbar spinal stenosis (a narrowing of the spine that puts pressure on nerves). One group will get standard decompression (relieving pressure), the other group will get that plus screws and rods to stabilize the spine. The goal is to see which leads to better outcomes.
Lahore, Punjab ProvinceAges 30–60 - NCT07045714Recruiting
Endoscopic back surgery for spinal stenosis
This study looks at a newer, less invasive type of back surgery called endoscopic laminotomy. It may help people with lumbar spinal stenosis (narrowing of the spinal canal) who still have leg or back pain after trying physical therapy and pain medicines for at least 3 months.
San Pedro Garza García, Nuevo LeónAges 18–74 - NCT04075539RecruitingPhase 3
At-home cycling for lumbar spinal stenosis pain
This study tests whether an at-home cycling program can reduce leg and back pain caused by lumbar spinal stenosis. It aims to see if regular, supervised cycling helps people walk and function better.
Paris, Île-de-France RegionAges 50 years+ - NCT06393959Recruiting
Injection treatment for lumbar spinal stenosis pain
This study tests whether an injection treatment can help relieve back and leg pain caused by a narrowed spinal canal in the lower back. It is for people whose pain has lasted at least 3 months and who have not had back surgery.
Ankara, TürkiyeAges 18–90 - NCT07139938Recruiting
Spinal decompression without implants for lumbar stenosis
This trial tests whether removing pressure on spinal nerves alone, without any hardware, can help fix spine balance and reduce pain in people with lumbar stenosis. It is for those who have had leg pain or trouble walking for at least 3 months and plan to have surgery without implants.
MoscowAges 18 years+ - NCT07489001Recruiting
Comparing opioid-free to standard anesthesia for back surgery
This study compares two types of anesthesia for lower back surgery: one that uses opioids and one that does not. The goal is to see which approach controls pain better with fewer side effects.
Istanbul, MaltepeAges 18–75 - NCT07469020Recruiting
Cle-pad study: Checking leg artery health in spine surgery patients
This study is looking at how common blockages in leg arteries (peripheral artery disease, or PAD) are in people who are having surgery for lumbar spinal stenosis or had surgery less than 3 months ago. If you qualify, it may help doctors better understand and treat this condition.
LilleAges 18 years+ - NCT06907849Enrolling by invitationPhase 2
Imaging amyloid in spinal stenosis and carpal tunnel
This trial tests a special scan that uses a radioactive tracer to look for amyloid protein deposits in people who have had surgery for lumbar spinal stenosis (narrowing of the spine in the lower back) or carpal tunnel syndrome. The goal is to see if the scan can detect these deposits, which may be linked to ongoing orthopedic issues.
Knoxville, TennesseeAges 60 years+ - NCT06394089Recruiting
Spine surgery study for stenosis with mild slippage
This study tests a minimally invasive spine surgery (unilateral biportal endoscopy) to see if it works well for people with lumbar spinal stenosis who also have a mild vertebra slippage (spondylolisthesis). The goal is to improve leg symptoms like pain or numbness when walking.
Beijing, Beijing MunicipalityAges 50–80 - NCT06591442Enrolling by invitation
Spinal Fusion Recovery in Older Adults
This study is looking at how older adults recover after spinal fusion surgery, a type of back surgery that connects bones in the spine. The goal is to find factors that help people heal faster and feel better afterward.
Wuhan, HubeiAges 60 years+ - NCT04273828Recruiting
Study of muscle changes in chronic low back pain surgery
This study looks at how muscle degeneration relates to nerve-related symptoms in people with chronic low back pain. You may be eligible if you’ve tried non-surgical care but still need surgery to relieve nerve pressure.
São Paulo, São PauloAges 18 years+ - NCT07776366Recruiting
Study of disc protein levels and disc wear
This study looks at a protein called periostin in the discs of the lower back to see if it relates to how worn down the discs are, which might help improve future treatments.
Daegu, DaeguAges 20–80 - NCT06034405Recruiting
Checking spine tissue for heart amyloidosis signs
This trial is looking at leftover tissue from past spine surgeries to see if it contains signs of a heart condition called TTR amyloidosis. It may help find people who have this condition early.
Beverly Hills, CaliforniaAges 50 years+ - NCT05527145Recruiting
Non-surgical spacer for spinal stenosis causing leg pain
This trial tests a minimally invasive (“through the skin”) procedure that places a small spacer between back bones to relieve lumbar spinal stenosis symptoms like leg pain when walking. It may help people who still need surgery based on their symptoms and MRI findings but may be treated without open surgery.
RomeAges 50–85
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Common questions
- Are there clinical trials for lumbar stenosis?
- Yes. Clin2 currently lists 62 recruiting lumbar stenosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lumbar stenosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lumbar stenosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.