Clinical trials
Lymph Node Dissection clinical trials
Below are recruiting lymph node dissection clinical trials, each written for real people, not researchers. We’re tracking 120 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04527419Recruiting
Surgery for early lung adenocarcinoma with specific CT findings
This study looks at whether people with a very early type of lung cancer can safely have curative surgery when their CT scan shows a ground-glass type spot with certain size and shape measurements. It aims to help doctors choose the right surgery approach based on the scan features and final pathology.
ShanghaiAges 18–75 - NCT06593665RecruitingPhase 3
Morphine in spine vs. IV methadone for testicular cancer surgery pain
This trial compares two ways to manage pain after surgery for testicular cancer: a single injection of morphine into the spine (intrathecal morphine) vs. methadone given through an IV during surgery. The goal is to see which provides better pain relief and fewer side effects.
Indianapolis, IndianaAges 18–80 - NCT06144736RecruitingPhase 2
Surgery for stage 2 seminoma testicular cancer trial
This trial is testing whether removing affected lymph nodes with surgery (RPLND) works well alone for seminoma testicular cancer that has spread to nearby nodes but is still relatively small. It is for patients who have not had extensive chemo or radiation.
DüsseldorfAges 18–99 - NCT06353906RecruitingPhase 2
Chemo plus immunotherapy for advanced penile cancer
This trial tests a combination of two chemotherapy drugs (carboplatin and paclitaxel) plus the immunotherapy drug pembrolizumab (Keytruda) for penile cancer that has spread to nearby lymph nodes. The goal is to see if this combination can shrink or control the cancer before or after surgery.
LeuvenAges 18 years+ - NCT06309745Recruiting
Lowering treatment for Stage II testicular cancer
This trial tests lowering the intensity of treatment (de-escalation) for Stage II seminoma, a type of testicular cancer. You may receive either a surgery to remove lymph nodes or a single round of chemotherapy (carboplatin), instead of more aggressive standard treatments, to see if it's safe and effective.
LondonAges 16 years+ - NCT06144164RecruitingPhase 3
Preventing Lymphedema After Breast Cancer Surgery
This trial tests a comprehensive prevention program to reduce lymphedema—a swelling in the arm—after breast cancer surgery that removes lymph nodes. If you qualify, you'll learn special exercises and care steps to lower your risk.
Basking Ridge, New JerseyAges 18–75 - NCT05593458RecruitingPhase 3
Stomach cancer surgery before chemo: artery-based or drip chemo
This trial compares two ways of giving chemotherapy before surgery for locally advanced stomach or stomach–esophagus cancer: chemo sent through an artery versus chemo given through an IV line. It also studies adding PD-1 immunotherapy to see which approach works better and is safer.
Hangzhou, ZhejiangAges 18–75 - NCT05412225RecruitingPhase 1
Pre-surgery radiation, then mastectomy and immediate breast reconstruction
This Phase 1 study looks at giving radiation before surgery for people with locally advanced breast cancer, then performing a mastectomy and immediate reconstruction. It aims to see whether this combined approach can shrink the cancer before surgery and safely allow reconstruction afterward.
Basking Ridge, New JerseyAges 18 years+ - NCT05319015RecruitingPhase 2
Combination drug therapy before surgery for kidney cancer with vena cava clot
This trial tests two drugs, lenvatinib and pembrolizumab, given before surgery to shrink kidney cancer that has spread into the large vein carrying blood to the heart (the vena cava). The goal is to see if this approach makes surgery more effective and improves outcomes.
Dallas, TexasAges 18 years+ - NCT05345158Recruiting
Robotic surgery first for early-stage seminoma testicular cancer
This trial studies whether a robotic operation (removing cancerous lymph nodes in the back of the belly) is a good first treatment for certain early-stage testicular seminoma cases. It aims to cure cancer while avoiding or delaying other treatments, and uses follow-up plans to check results.
Toronto, OntarioAges 18 years+ - NCT04364373Recruiting
Test of different lymph node surgery for left colon cancer
This study compares two types of lymph node removal during surgery for left-sided colon cancer. It aims to see which surgical approach may work better while ensuring you can still safely complete chemotherapy.
MoscowAges 18–75 - NCT04174079Recruiting
Chemotherapy after esophagus surgery for lymph node spread
This trial studies whether adding chemotherapy after surgery for esophageal squamous cell cancer can reduce the chance the cancer returns. It focuses on people whose surgery removed cancerous lymph nodes and who are healthy enough to tolerate chemotherapy.
Guangzhou, GuangdongAges 18–75 - NCT02743832Recruiting
Personalized surgery planning for early mouth cancer
This study helps doctors plan surgery more individually for early-stage oral (mouth) squamous cell carcinoma. It focuses on using tumor features found during evaluation to guide surgical decisions, aiming to improve treatment accuracy.
Guangzhou, GuangdongAges 20–70 - NCT03534713RecruitingPhase 3
Cervical cancer treatment plan after lymph node spread
This trial tests a specific chemotherapy start (induction) followed by standard treatment for cervical cancer that has spread to lymph nodes near the aorta. It may help improve cancer control compared with standard timing/approach.
BordeauxAges 18 years+ - NCT07278726Recruiting
Targeted removal of only suspicious lymph nodes for early breast cancer
This trial is testing a targeted surgical approach to remove only the suspicious lymph nodes under the arm for people with early-stage, hormone receptor positive, HER2 negative breast cancer. The goal is to see if this less extensive surgery is safe and effective when there is limited lymph node involvement.
Bologna, ItalyAges 18–90 - NCT07304934Recruiting
New blood test model to check lymph node status in breast cancer
This study uses a blood test and imaging to predict whether breast cancer has spread to underarm lymph nodes, helping guide surgery. It may reduce unnecessary lymph node removal.
Hangzhou, ZhejiangAges 18 years+ - NCT06840418Recruiting
New imaging to find cancer spread in cervical cancer surgery
This study tests a new imaging technique (NIRFI with ICG dye) to help surgeons see if cervical cancer has spread to lymph nodes during your hysterectomy surgery. It may help guide more precise removal of affected nodes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06947096Enrolling by invitation
AI prediction of stomach cancer spread to lymph nodes
This study uses artificial intelligence to analyze your CT scan and predict whether stomach cancer has spread to lymph nodes behind your belly. The goal is to help doctors decide if you need more extensive surgery.
Shijiazhuang, None SelectedAges 18–80 - NCT04073706RecruitingPhase 3
Sentinel node biopsy for early womb cancer
This trial tests whether a less invasive way to check if cancer has spread to lymph nodes (sentinel node biopsy) works as well as the standard method. It is for people with early-stage endometrial cancer having surgery.
Houston, TexasAges 18 years+ - NCT05976412Recruiting
Radiation to lymph nodes after surgery for higher-risk breast cancer
This trial looks at whether adding targeted radiation to lymph nodes after breast surgery can lower the chance of breast cancer coming back in people with higher-risk, node-negative disease. If you qualify, you may get a planned radiation approach designed for prevention, not treatment of spread.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07328243Recruiting
New treatment for thyroid cancer that spread to neck lymph nodes
This study tests a minimally invasive treatment called irreversible electroporation for thyroid cancer that has come back or spread to lymph nodes in the neck. It may be an option for people who can't have another surgery or for whom radioactive iodine therapy hasn't worked.
Guangzhou, GuangdongAges 18 years+ - NCT07615374Recruiting
Combined laparo-endoscopic sentinel node surgery for early stomach cancer
This trial tests a surgical technique that combines two types of minimally invasive procedures (laparoscopy and endoscopy) to find and remove the first lymph node that might contain cancer (called the sentinel lymph node) in people with early stomach cancer. The goal is to remove only the necessary lymph nodes, potentially reducing side effects while ensuring the cancer hasn't spread.
Changchun, JilinAges Any age - NCT07835087Recruiting
Guided removal of sentinel lymph nodes in early stomach cancer
This trial tests a new image-guided method to find and remove sentinel lymph nodes (the first nodes where cancer might spread) in people with early stomach cancer. The goal is to precisely remove only the affected lymph nodes during surgery, which might mean a less extensive operation and fewer side effects.
BeijingAges 18–80 - NCT05333523RecruitingPhase 3
Personalized neck radiation using a lymph node sentinel biopsy
This Phase 3 trial tests whether guiding neck radiation by checking the “sentinel” lymph node can target treatment more precisely in certain larynx, hypopharynx, or oropharynx cancers. It aims to improve control while potentially reducing unnecessary radiation to areas that don’t need it.
AmsterdamAges 18 years+
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Common questions
- Are there clinical trials for lymph node dissection?
- Yes. Clin2 currently lists 120 recruiting lymph node dissection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lymph node dissection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lymph node dissection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.