Clinical trials
Massive Rotator Cuff Tear clinical trials
Below are recruiting massive rotator cuff tear clinical trials, each written for real people, not researchers. We’re tracking 33 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05981833Recruiting
Donated skin graft for large rotator cuff tears
This study tests whether adding a donated skin graft during rotator cuff repair helps heal large tears better than repair alone. It may be an option for people with a first-time, large rotator cuff tear who have moderate to severe fatty changes in the muscle.
Scottsdale, ArizonaAges 30–75 - NCT04571918Recruiting
Arthroscopic repair using a biodegradable spacer for severe shoulder tears
This study looks at an arthroscopic procedure (a minimally invasive surgery) that includes cleaning the tear and placing a biodegradable spacer to treat painful, severe rotator cuff tears. It may help reduce pain and improve shoulder function in people who have tried non-surgical treatments but still have symptoms.
ArendalAges 60–85 - NCT07004218Enrolling by invitation
Ultrasound follow-up after massive rotator cuff tear surgery
This trial uses ultrasound imaging to check how the shoulder heals over the first year after surgery for a large tear in the rotator cuff (the group of tendons that helps lift and rotate your arm). The goal is to better understand recovery and improve care for people with this injury.
Çankaya, AnkaraAges 18–80 - NCT07375277Recruiting
Biceps tendon transfer for large rotator cuff tears
This study tests a new surgical technique that uses your biceps tendon to help repair a large rotator cuff tear. It may be an option if you have not improved after at least 3 months of other treatments.
BalıkesirAges 18 years+ - NCT06817616Recruiting
Rotator cuff repair with stem cells for large shoulder tears
This trial tests whether adding umbilical cord stem cells to standard arthroscopic rotator cuff repair helps heal large or massive tears better. It may be an option if you have had shoulder pain for at least three months and other treatments haven't worked.
Seoul, KoreaAges 19 years+ - NCT07208448Recruiting
Study on a new shoulder spacer for torn rotator cuff
This trial tests a new biodegradable spacer for the shoulder in people with a full-thickness rotator cuff tear. It may help relieve pain and improve shoulder function without the need for more invasive surgery.
AshdodAges 50 years+ - NCT03617562Recruiting
Compare two surgeries for large rotator cuff tears
This trial compares two different operations to treat large, hard-to-repair rotator cuff tears. If your tear is too damaged to be repaired in the usual way, the study tests whether one surgical approach may work better than a partial repair.
Toronto, OntarioAges 18–65 - NCT05439850RecruitingPhase 4
Bioinductive patch for severe torn shoulder tendons
This trial studies a special patch placed during minimally invasive shoulder surgery to help heal full-thickness rotator cuff tears. It may help people whose tears are large or massive and who already tried non-surgical treatment without enough improvement.
Detroit, MichiganAges 18 years+ - NCT05450510Recruiting
Testing slow vs faster rehab for severe shoulder tears
This study compares two physical therapy rehab plans to see which helps people recover better after a severe, irreparable rotator cuff tear. It may help you find the pace of rehab that works best for your shoulder and daily function.
KırşehirAges 18–65 - NCT05624164Recruiting
Microfracture surgery to help rotator cuff tears heal
This trial studies a specific surgical technique (microfracture) to help the rotator cuff heal after repair. You might be eligible if you have a rotator cuff tear of a certain size on MRI and have not improved with non-surgical treatments.
Nantong, JiangsuAges 18–65 - NCT05807854Recruiting
Surgery options for large, repairable shoulder tendon tears
This trial compares two different ways to repair a large, repairable rotator cuff (shoulder tendon) tear. It may help you understand which surgical approach leads to better recovery after non-surgical treatments have already failed.
Portland, OregonAges 60–80 - NCT05855759Recruiting
New graft to help repair large rotator cuff tears
This trial studies a special “acellular” (cell-free) skin-derived graft combined with healing-stimulating materials to improve healing and function after surgery for large rotator cuff tears. It may help people with serious tendon damage in the shoulder, but only if their tear type and health situation fit the study rules.
Bologna, BOAges 18–65 - NCT05896475Recruiting
Looking for who may develop shoulder pain from silent tears
This study looks at risk factors that predict when an “asymptomatic” (painless) rotator cuff tear might start causing symptoms. You may benefit by getting careful assessment and monitoring of your shoulder health over time.
Ghent, Oost-VlaanderenAges 55–100 - NCT05925881Recruiting
Surgery for large shoulder tears: two repair methods compared
This trial compares two surgical approaches to fix a very large, irreparable rotator cuff tear. It may help people understand which technique leads to better shoulder function and recovery.
Halifax, Nova ScotiaAges 18 years+ - NCT06076902Recruiting
Patch study for large rotator cuff tear repair
This study tests whether adding a patch to standard rotator cuff repair helps large tears heal better. It's for adults who need their first surgery for a tear involving at least two tendons.
Frauenfeld, ThurgauAges 30–75 - NCT06774820Recruiting
Biceps tendon surgery alongside rotator cuff repair study
This study is testing a new surgical technique for repairing a torn rotator cuff while also addressing the biceps tendon. It aims to see if adding this biceps procedure improves recovery and outcomes for people with full-thickness tears.
AnnecyAges 40 years+ - NCT07005063Recruiting
Rotator cuff repair with FiberLocker patch
This trial tests a new patch, FiberLocker, to help repair a torn rotator cuff tendon. It's for people who need surgery for a full-thickness tear caused by an injury, and aims to improve healing.
Zurich, Canton of ZurichAges 40–65 - NCT07154641Recruiting
Shoulder tendon transfer vs. reconstruction for large tears
This trial compares two surgeries to repair large rotator cuff tears (torn shoulder tendons). One moves a nearby tendon, the other uses a patch. It aims to find which works better for pain and mobility.
Athens, AtticaAges 18 years+ - NCT07546084Recruiting
Exercise Program for Rotator Cuff Shoulder Pain
This study tests whether a special exercise program that trains you to focus your attention in different ways can reduce shoulder pain and improve function. You'll do exercises designed to help your rotator cuff (the muscles that stabilize your shoulder) while learning to shift your mental focus during movement.
IstanbulAges 18–65 - NCT05566470Enrolling by invitation
Study of brain-muscle changes after major rotator cuff surgery
This study looks at how the brain and muscles work, along with mood and pain, in people after rotator cuff surgery for a major tear. It may help researchers understand recovery problems and psychological effects that can happen after surgery.
AnkaraAges 30–65 - NCT07377292Recruiting
Core exercises for rotator cuff tears
This trial tests if core stabilization exercises help people with a partial rotator cuff tear (a small tear in the shoulder muscle) feel better and move easier. It may be an option if you haven't had recent treatments or injections for your shoulder.
KırşehirAges 40–60 - NCT07390396Recruiting
Shock wave therapy plus exercises for shoulder pain
This trial tests whether adding shock wave therapy to standard exercises helps people with chronic rotator cuff tendon pain. If you have had shoulder pain for over 3 months due to a confirmed tendon problem, this might be an option for you.
Minya, Menia GovernorateAges 30–55 - NCT07415967Recruiting
Dual-task exercise for rotator cuff shoulder pain
This study tests an exercise program that combines shoulder movements with mental tasks (like counting or naming things) to improve pain and function. It is for people with ongoing shoulder pain from common rotator cuff problems.
IstanbulAges 18–65 - NCT06741527Recruiting
Integrity Implant for rotator cuff repair study
This study is testing a new shoulder implant called the Integrity Implant System to see how well it works for people with rotator cuff tears. It may be a good fit if you need surgery to repair your torn tendon and meet the safety requirements.
Gilbert, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for massive rotator cuff tear?
- Yes. Clin2 currently lists 33 recruiting massive rotator cuff tear studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a massive rotator cuff tear trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a massive rotator cuff tear trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.