Clinical trials
Mechanical Ventilator Weaning clinical trials
Below are recruiting mechanical ventilator weaning clinical trials, each written for real people, not researchers. We’re tracking 67 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07613021Recruiting
Breathing Muscle Training to Help ICU Patients Stop Using Ventilators
This trial tests whether special breathing exercises can help patients who have been on a breathing machine (ventilator) in the ICU for at least 3 days get off the machine more successfully. The exercises focus on strengthening the muscles you use to breathe in.
ChalcisAges 18 years+ - NCT05751863Recruiting
Sedation-first vs usual care in ventilated trauma patients
This study compares how pain medicine and calming medicine are started in critically injured (trauma) adults who are on a breathing machine. It aims to see whether a specific “analgesia-first” approach can improve comfort and support breathing weaning.
Long Beach, CaliforniaAges 18 years+ - NCT06009731Recruiting
Diaphragm ultrasound during breathing trial
This study uses a special ultrasound technique to look at how your diaphragm (the main breathing muscle) moves while you try breathing on your own. It may help doctors better understand when patients are ready to come off the breathing machine.
AmiensAges 18 years+ - NCT07709182Recruiting
Guided breathing machine settings for weaning off ventilation
This trial compares two ways of adjusting the breathing machine to help patients come off it more smoothly. It uses a special measurement (airway occlusion pressure) to guide settings, which may help you breathe on your own faster.
Tanta, Al GharbiaAges 21 years+ - NCT05687292Recruiting
Decision tool to shorten breathing machine time in children
This study tests whether a computer “decision support” tool can help doctors safely reduce how long a child stays on a breathing machine after heart surgery. It may help children get off mechanical ventilation sooner and recover faster.
Boston, MassachusettsAges 1 day–12 years - NCT07710469Enrolling by invitation
Weighted blanket for comfort during vent weaning
This trial is testing whether a special weighted blanket can help you feel more calm and comfortable as doctors slowly reduce the support from your breathing machine. It's for people who are on a ventilator and ready to start the weaning process.
Boston, MassachusettsAges 18 years+ - NCT05990348Recruiting
Comparing two breathing support methods for weaning from ventilator
This study compares two ways of helping patients breathe on a ventilator after a failed attempt to come off the machine. It looks at how the diaphragm and rib muscles work during each method to find the best approach for weaning.
RomeAges 18 years+ - NCT06499389Recruiting
Breathing muscle therapy for hard-to-wean ICU patients
This study tests a special breathing therapy for intensive care patients who are having trouble coming off the ventilator. If you have weak muscles or a weak cough, the therapy aims to strengthen your breathing so you can recover faster.
Lyon, FranceAges 18 years+ - NCT06368089Recruiting
Breathing muscle training for patients on a ventilator
This study tests two types of breathing exercises for people who have been on a breathing machine (ventilator) for more than 48 hours and are ready to start breathing on their own. The goal is to see which exercise helps them get off the ventilator faster.
SongkhlaAges 40–80 - NCT05226247Recruiting
Check whether careful weaning prevents lung fluid buildup
This study looks at people on a breathing machine for more than 48 hours who are starting a “spontaneous breathing trial,” a test used to see if they can breathe on their own. It focuses on those at higher risk of “weaning-induced pulmonary edema,” meaning fluid can collect in the lungs during the weaning process.
DijonAges 18 years+ - NCT06424314Recruiting
Trial on why some patients fail to come off a ventilator
This trial is studying why some people have trouble coming off a breathing machine (ventilator). It's for patients who've been on a ventilator for at least 2 days and don't have certain other conditions.
Guangzhou, GuangdongAges 18 years+ - NCT06494215Recruiting
Comparing methods to measure lung air distribution in ventilated patients
This study tests different ways to measure how air is distributed in the lungs of patients on a breathing machine (ventilator) as they are being weaned off. It may help doctors better understand lung function during recovery.
São PauloAges 18 years+ - NCT07519512Recruiting
Early Switch to Assisted Breathing in ICU Patients
This study tests whether moving ICU patients from fully machine-controlled breathing to partially assisted breathing earlier helps them get off ventilators successfully. The goal is to see if this approach reduces the time patients need mechanical ventilation.
Nanjing, JiangsuAges 18 years+ - NCT06837402Enrolling by invitation
Non-invasive ventilation in Argentine ICUs: an observational study
This study looks at how non-invasive breathing support (like a mask or machine) is used in ICUs across Argentina. It helps doctors understand patterns of care so they can improve treatment for patients with breathing problems.
CABA, Buenos AiresAges 18 years+ - NCT07114289Recruiting
Breathing test methods for overweight patients on ventilators
This study compares two ways of testing if overweight or obese patients can breathe on their own after being on a ventilator. You will be randomly assigned to one of two breathing trials (pressure support or a T-piece) to see which works better for helping you get off the ventilator.
TaipeiAges 18 years+ - NCT07771101Recruiting
Using a pain monitor to time breathing-tube removal
This study tests whether a special monitor can help doctors know when it's safe to take a breathing tube out after surgery in the ICU. The monitor looks at pain signals, and the goal is to make the process of breathing on your own again more comfortable.
SeoulAges 18 years+ - NCT06816706Recruiting
Comparing two oxygen methods during breathing trials
This study compares two ways of giving oxygen (high-flow through the nose vs. a T-piece) to help patients come off a breathing machine safely. It aims to see which method works better during a test of your ability to breathe on your own.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07002710Recruiting
Long-term ventilation and inflammation study
This study looks at how long-term inflammation affects the breathing of people who have been on a ventilator for 10 days or more. It aims to help doctors better understand and support your recovery.
TaipeiAges 20 years+ - NCT05670093Recruiting
Testing pressure support to ease breathing muscle work
This trial looks at a breathing-support setting that may reduce the effort of your breathing muscles while you’re coming off a ventilator. It’s meant for people who have been on a breathing machine for more than 24 hours during the “weaning” phase.
SolnaAges 18 years+
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Common questions
- Are there clinical trials for mechanical ventilator weaning?
- Yes. Clin2 currently lists 67 recruiting mechanical ventilator weaning studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanical ventilator weaning trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanical ventilator weaning trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.